Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7N7O
DownloadVisualize
BU of 7n7o by Molmil
Crystal Structure of PI5P4KIIAlpha complex with Palbociclib
Descriptor: 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-10
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
7N7J
DownloadVisualize
BU of 7n7j by Molmil
Crystal Structure of PI5P4KIIAlpha complex with AMPPNP
Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ...
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-10
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
7N80
DownloadVisualize
BU of 7n80 by Molmil
Crystal Structure of PI5P4KIIBeta
Descriptor: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-11
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
7N7M
DownloadVisualize
BU of 7n7m by Molmil
Crystal Structure of PI5P4KIIAlpha complex with BI-2536
Descriptor: 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-10
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
7N7K
DownloadVisualize
BU of 7n7k by Molmil
Crystal Structure of PI5P4KIIAlpha complex with AMPPNP
Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ...
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-10
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
7N7L
DownloadVisualize
BU of 7n7l by Molmil
Crystal Structure of PI5P4KIIAlpha complex with BI-D1870
Descriptor: (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-one, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-10
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
7N71
DownloadVisualize
BU of 7n71 by Molmil
Crystal Structure of PI5P4KIIAlpha
Descriptor: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-09
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
3P39
DownloadVisualize
BU of 3p39 by Molmil
Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
Descriptor: Nonstructural protein 1
Authors:Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
Deposit date:2010-10-04
Release date:2011-10-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3P31
DownloadVisualize
BU of 3p31 by Molmil
Crystal structure of the NS1 effector domain from influenza A/Vietnam/1203/2004 (H5N1) virus
Descriptor: Nonstructural protein 1, THIOCYANATE ION
Authors:Chen, S, Xiao, Y.B, Ponnusamy, R, Hilgenfeld, R.
Deposit date:2010-10-04
Release date:2011-10-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3P38
DownloadVisualize
BU of 3p38 by Molmil
Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus
Descriptor: Nonstructural protein 1
Authors:Chen, S, Xiao, Y.B, Bricogne, G, Sharff, A.J, Hilgenfeld, R.
Deposit date:2010-10-04
Release date:2011-10-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:X-ray structures of the NS1 effector domain from highly pathogenic influenza A/Vietnam/1203/2004 (H5N1) virus
To be Published
3O5Z
DownloadVisualize
BU of 3o5z by Molmil
Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphatidylinositol 3-kinase regulatory subunit beta
Authors:Chen, S, Xiao, Y, Ponnusamy, R, Tan, J, Lei, J, Hilgenfeld, R.
Deposit date:2010-07-28
Release date:2011-08-10
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85 beta subunit
Acta Crystallogr.,Sect.F, 67, 2011
7DHY
DownloadVisualize
BU of 7dhy by Molmil
Arsenic-bound p53 DNA-binding domain mutant G245S
Descriptor: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
Authors:Chen, S, Lu, M.
Deposit date:2020-11-18
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021
7DHZ
DownloadVisualize
BU of 7dhz by Molmil
Arsenic-bound p53 DNA-binding domain mutant R249S
Descriptor: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
Authors:Chen, S, Lu, M.
Deposit date:2020-11-18
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021
6PLL
DownloadVisualize
BU of 6pll by Molmil
Crystal structure of the ZIG-8 IG1 homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Zwei Ig domain protein zig-8
Authors:Cheng, S, Ozkan, E.
Deposit date:2019-07-01
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7Y24
DownloadVisualize
BU of 7y24 by Molmil
Cryo-EM structure of the octreotide-bound SSTR2-miniGo-scFv16 complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ...
Authors:Chen, S, Zheng, S.
Deposit date:2022-06-09
Release date:2022-10-19
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Molecular basis for the selective G protein signaling of somatostatin receptors.
Nat.Chem.Biol., 19, 2023
7Y27
DownloadVisualize
BU of 7y27 by Molmil
Cryo-EM structure of the SST-14-bound SSTR2-miniGq-scFv16 complex
Descriptor: CHOLESTEROL, Engineered Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Chen, S, Zheng, S.
Deposit date:2022-06-09
Release date:2022-10-19
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Molecular basis for the selective G protein signaling of somatostatin receptors.
Nat.Chem.Biol., 19, 2023
7Y26
DownloadVisualize
BU of 7y26 by Molmil
Cryo-EM structure of the octreotide-bound SSTR2-miniGq-scFv16 complex
Descriptor: Engineered Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Chen, S, Zheng, S.
Deposit date:2022-06-09
Release date:2022-10-19
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for the selective G protein signaling of somatostatin receptors.
Nat.Chem.Biol., 19, 2023
6J20
DownloadVisualize
BU of 6j20 by Molmil
Crystal structure of the human NK1 substance P receptor
Descriptor: 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin
Authors:Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q.
Deposit date:2018-12-30
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography.
Nat Commun, 10, 2019
7BVW
DownloadVisualize
BU of 7bvw by Molmil
Crystal structure of the RING-H2 domain of Arabidopsis RMR1
Descriptor: AT5G66160 protein, SODIUM ION, ZINC ION
Authors:Chen, S, Wong, K.B.
Deposit date:2020-04-12
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The RING-finger of AtRMR1 (Arabidopsis receptor-homology-transmembrane-RING-H2 sorting receptor 1) is an E3 ligase that mediate its trafficking
To Be Published
6J21
DownloadVisualize
BU of 6j21 by Molmil
Crystal structure of the human NK1 substance P receptor
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-[[(2~{R},3~{S})-2-[(1~{R})-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one, Substance-P receptor,Endolysin
Authors:Chen, S, Lu, M, Zhang, H, Wu, B, Zhao, Q.
Deposit date:2018-12-30
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography.
Nat Commun, 10, 2019
1BH6
DownloadVisualize
BU of 1bh6 by Molmil
SUBTILISIN DY IN COMPLEX WITH THE SYNTHETIC INHIBITOR N-BENZYLOXYCARBONYL-ALA-PRO-PHE-CHLOROMETHYL KETONE
Descriptor: CALCIUM ION, N-BENZYLOXYCARBONYL-ALA-PRO-3-AMINO-4-PHENYL-BUTAN-2-OL, SODIUM ION, ...
Authors:Eschenburg, S, Genov, N, Wilson, K.S, Betzel, C.
Deposit date:1998-06-15
Release date:1998-11-04
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg.
Eur.J.Biochem., 257, 1998
1EJD
DownloadVisualize
BU of 1ejd by Molmil
Crystal structure of unliganded mura (type1)
Descriptor: CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE
Authors:Eschenburg, S, Schonbrunn, E.
Deposit date:2000-03-02
Release date:2000-10-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1EJC
DownloadVisualize
BU of 1ejc by Molmil
Crystal structure of unliganded mura (type2)
Descriptor: GLYCEROL, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE
Authors:Eschenburg, S, Schonbrunn, E.
Deposit date:2000-03-02
Release date:2000-10-25
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparative X-ray analysis of the un-liganded fosfomycin-target murA.
Proteins, 40, 2000
1I6U
DownloadVisualize
BU of 1i6u by Molmil
RNA-PROTEIN INTERACTIONS: THE CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN S8/RRNA COMPLEX FROM METHANOCOCCUS JANNASCHII
Descriptor: 16S RRNA FRAGMENT, 30S RIBOSOMAL PROTEIN S8P, SULFATE ION
Authors:Tishchenko, S, Nikulin, A, Fomenkova, N, Nevskaya, N, Nikonov, O, Dumas, P, Moine, H, Ehresmann, B, Ehresmann, C, Piendl, W, Lamzin, V, Garber, M, Nikonov, S.
Deposit date:2001-03-05
Release date:2001-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii.
J.Mol.Biol., 311, 2001
1R8O
DownloadVisualize
BU of 1r8o by Molmil
Crystal structure of an unusual Kunitz-type trypsin inhibitor from Copaifera langsdorffii seeds
Descriptor: Kunitz trypsin inhibitor
Authors:Krauchenco, S, Nagem, R.A.P, da Silva, J.A, Marangoni, S, Polikarpov, I.
Deposit date:2003-10-27
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Three-dimensional structure of an unusual Kunitz (STI) type trypsin inhibitor from Copaifera langsdorffii.
Biochimie, 86, 2004

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon