8EQA
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![BU of 8eqa by Molmil](/molmil-images/mine/8eqa) | Crystal structure of human anti-N1 neuraminidase 2H08 Fab | Descriptor: | 2H08 Fab heavy chain, 2H08 Fab light chain, ZINC ION | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2022-10-07 | Release date: | 2023-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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8EQC
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![BU of 8eqc by Molmil](/molmil-images/mine/8eqc) | Crystal structure of human anti-N1 neuraminidase 3H03 Fab | Descriptor: | 3H03 Fab heavy chain, 3H03 Fab light chain, PHOSPHATE ION | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2022-10-07 | Release date: | 2023-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
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3QG6
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![BU of 3qg6 by Molmil](/molmil-images/mine/3qg6) | Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody | Descriptor: | AP4-24H11 Heavy Chain, AP4-24H11 Light Chain, Agr autoinducing peptide, ... | Authors: | Kirchdoerfer, R.N, Janda, J.D, Kaufmann, G.F, Wilson, I.A. | Deposit date: | 2011-01-24 | Release date: | 2011-03-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody. J.Biol.Chem., 286, 2011
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3QL0
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![BU of 3ql0 by Molmil](/molmil-images/mine/3ql0) | Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | Deposit date: | 2011-02-02 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science, 332, 2011
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3T0X
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![BU of 3t0x by Molmil](/molmil-images/mine/3t0x) | Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red | Descriptor: | 1,2-ETHANEDIOL, 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, Immunoglobulin variable lambda domain M8VLA4(S55P), ... | Authors: | Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P. | Deposit date: | 2011-07-20 | Release date: | 2012-03-21 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red. Biochemistry, 51, 2012
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3T0V
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![BU of 3t0v by Molmil](/molmil-images/mine/3t0v) | Unliganded fluorogen activating protein M8VL | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | Authors: | Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P. | Deposit date: | 2011-07-20 | Release date: | 2012-03-21 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red. Biochemistry, 51, 2012
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3T0W
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![BU of 3t0w by Molmil](/molmil-images/mine/3t0w) | Fluorogen activating protein M8VL in complex with dimethylindole red | Descriptor: | 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | Authors: | Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P. | Deposit date: | 2011-07-20 | Release date: | 2012-03-21 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red. Biochemistry, 51, 2012
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3QQB
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![BU of 3qqb by Molmil](/molmil-images/mine/3qqb) | Crystal structure of HA2 R106H mutant of H2 hemagglutinin, neutral pH form | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Xu, R, Wilson, I.A. | Deposit date: | 2011-02-15 | Release date: | 2011-03-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin. J.Virol., 85, 2011
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3RG1
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![BU of 3rg1 by Molmil](/molmil-images/mine/3rg1) | Crystal structure of the RP105/MD-1 complex | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CD180 molecule, LY86 protein, ... | Authors: | Yoon, S.I, Hong, M, Wilson, I.A. | Deposit date: | 2011-04-07 | Release date: | 2011-08-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1. Nat.Struct.Mol.Biol., 18, 2011
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3R06
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![BU of 3r06 by Molmil](/molmil-images/mine/3r06) | |
3TV3
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![BU of 3tv3 by Molmil](/molmil-images/mine/3tv3) | |
3SDY
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![BU of 3sdy by Molmil](/molmil-images/mine/3sdy) | |
3QQI
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![BU of 3qqi by Molmil](/molmil-images/mine/3qqi) | |
3QQE
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![BU of 3qqe by Molmil](/molmil-images/mine/3qqe) | Crystal structure of HA2 R106H mutant of H2 hemagglutinin, re-neutralized form | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Xu, R, Wilson, I.A. | Deposit date: | 2011-02-15 | Release date: | 2011-03-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin. J.Virol., 85, 2011
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1THZ
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![BU of 1thz by Molmil](/molmil-images/mine/1thz) | Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening | Descriptor: | 2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC ACID, Bifunctional purine biosynthesis protein PURH, POTASSIUM ION | Authors: | Xu, L, Li, C, Olson, A.J, Wilson, I.A. | Deposit date: | 2004-06-01 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening. J.Biol.Chem., 279, 2004
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3QQO
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![BU of 3qqo by Molmil](/molmil-images/mine/3qqo) | |
3QL3
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![BU of 3ql3 by Molmil](/molmil-images/mine/3ql3) | Re-refined coordinates for PDB entry 1RX2 | Descriptor: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | Authors: | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | Deposit date: | 2011-02-02 | Release date: | 2011-04-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science, 332, 2011
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3UBJ
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![BU of 3ubj by Molmil](/molmil-images/mine/3ubj) | Influenza hemagglutinin from the 2009 pandemic in complex with ligand LSTa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | Authors: | Xu, R, Wilson, I.A. | Deposit date: | 2011-10-24 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic. J.Virol., 86, 2012
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3UBN
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![BU of 3ubn by Molmil](/molmil-images/mine/3ubn) | Influenza hemagglutinin from the 2009 pandemic in complex with ligand 6SLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | Authors: | Xu, R, Wilson, I.A. | Deposit date: | 2011-10-24 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5079 Å) | Cite: | Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic. J.Virol., 86, 2012
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3TWI
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![BU of 3twi by Molmil](/molmil-images/mine/3twi) | Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores | Descriptor: | BclA protein, GLYCEROL, Variable lymphocyte receptor B | Authors: | Kirchdoerfer, R.N, Herrin, B.R, Han, B.W, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A. | Deposit date: | 2011-09-21 | Release date: | 2012-03-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores. Structure, 20, 2012
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3R08
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![BU of 3r08 by Molmil](/molmil-images/mine/3r08) | Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab | Descriptor: | Mouse anti-mouse CD3epsilon antibody 2C11 heavy chain, Mouse anti-mouse CD3epsilon antibody 2C11 light chain, T-cell surface glycoprotein CD3 epsilon chain | Authors: | Shore, D.A, Zhu, X, Wilson, I.A. | Deposit date: | 2011-03-07 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | T cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements. J.Biol.Chem., 287, 2012
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3R2X
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![BU of 3r2x by Molmil](/molmil-images/mine/3r2x) | |
3TYJ
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![BU of 3tyj by Molmil](/molmil-images/mine/3tyj) | Bacillus collagen-like protein of anthracis P159S mutant | Descriptor: | BclA protein | Authors: | Kirchdoerfer, R.N, Herrin, B.R, Han, B.W, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A. | Deposit date: | 2011-09-26 | Release date: | 2012-03-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores. Structure, 20, 2012
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3TCT
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![BU of 3tct by Molmil](/molmil-images/mine/3tct) | Structure of wild-type TTR in complex with tafamidis | Descriptor: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | Authors: | Connelly, S, Kelly, J.W, Wilson, I.A. | Deposit date: | 2011-08-09 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc.Natl.Acad.Sci.USA, 109, 2012
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3TWC
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![BU of 3twc by Molmil](/molmil-images/mine/3twc) | |