6IO6
| |
8IK3
| |
4DAC
| |
7L28
| Crystal structure of the catalytic domain of human PDE3A bound to Trequinsin | Descriptor: | (2E)-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one, ACETATE ION, MAGNESIUM ION, ... | Authors: | Horner, S.W, Garvie, C. | Deposit date: | 2020-12-16 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. Nat Commun, 12, 2021
|
|
7L27
| |
7L29
| |
7KWE
| Crystal structure of the catalytic domain of human PDE3A bound to DNMDP | Descriptor: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, ACETATE ION, MAGNESIUM ION, ... | Authors: | Horner, S.W, Garvie, C. | Deposit date: | 2020-11-30 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. Nat Commun, 12, 2021
|
|
7WS7
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, 510A5 light chain, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS6
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 510A5 heavy chain, 510A5 light chain, Spike protein S1 | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WSA
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS9
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS2
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 510A5 heavy chain, 510A5 light chain, Spike protein S1 | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS8
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS4
| Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS0
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS5
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS1
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
7WS3
| Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | Authors: | Guo, H, Gao, Y, Ji, X, Yang, H. | Deposit date: | 2022-01-28 | Release date: | 2022-06-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
|
|
6J72
| Crystal structure of IniA from Mycobacterium smegmatis with GTP bound | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ... | Authors: | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | Deposit date: | 2019-01-16 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mycobacterial dynamin-like protein IniA mediates membrane fission. Nat Commun, 10, 2019
|
|
6J73
| Crystal structure of IniA from Mycobacterium smegmatis | Descriptor: | Isoniazid inducible gene protein IniA | Authors: | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | Deposit date: | 2019-01-16 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.211 Å) | Cite: | Mycobacterial dynamin-like protein IniA mediates membrane fission. Nat Commun, 10, 2019
|
|
7E9Q
| Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... | Authors: | Wang, X.F, Zhu, Y.Q. | Deposit date: | 2021-03-04 | Release date: | 2022-03-09 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD Signal Transduct Target Ther, 7, 2022
|
|
7E9O
| Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... | Authors: | Wang, X.F, Zhu, Y.Q. | Deposit date: | 2021-03-04 | Release date: | 2022-03-09 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD Signal Transduct Target Ther, 7, 2022
|
|
7E9P
| |
7E9N
| Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... | Authors: | Wang, X.F, Zhu, Y.Q. | Deposit date: | 2021-03-04 | Release date: | 2022-04-06 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD Signal Transduct Target Ther, 7, 2022
|
|
7ENF
| Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab30, ... | Authors: | Wang, X.F, Zhu, Y.Q. | Deposit date: | 2021-04-16 | Release date: | 2022-04-06 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD Signal Transduct Target Ther, 7, 2022
|
|