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7CKY

Cryo-EM structure of PW0464 bound dopamine receptor DRD1-Gs signaling complex

Summary for 7CKY
Entry DOI10.2210/pdb7cky/pdb
EMDB information30394
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
Functional Keywordssignaling complex, cell cycle
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains5
Total formula weight158929.73
Authors
Yan, W.,Shao, Z. (deposition date: 2020-07-20, release date: 2021-03-03)
Primary citationXiao, P.,Yan, W.,Gou, L.,Zhong, Y.N.,Kong, L.,Wu, C.,Wen, X.,Yuan, Y.,Cao, S.,Qu, C.,Yang, X.,Yang, C.C.,Xia, A.,Hu, Z.,Zhang, Q.,He, Y.H.,Zhang, D.L.,Zhang, C.,Hou, G.H.,Liu, H.,Zhu, L.,Fu, P.,Yang, S.,Rosenbaum, D.M.,Sun, J.P.,Du, Y.,Zhang, L.,Yu, X.,Shao, Z.
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Cell, 184:943-956.e18, 2021
Cited by
PubMed: 33571432
DOI: 10.1016/j.cell.2021.01.028
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

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