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6LU6
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BU of 6lu6 by Molmil
Crystal structure of BPTF-BRD with ligand DCBPin5-2 bound
Descriptor: 6-[1-[3-(dimethylamino)propyl]indol-5-yl]-2-methylsulfonyl-N-propyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF
Authors:Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C.
Deposit date:2020-01-26
Release date:2021-04-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.970063 Å)
Cite:Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins
To Be Published
8WDW
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BU of 8wdw by Molmil
Crystal structure of a novel PU plastic degradation urethanase UMG-SP2 from uncultured bacterium
Descriptor: GLYCEROL, SULFATE ION, UMG-SP2, ...
Authors:Cong, L, Li, Z.S, Gao, J, Li, Q, Chen, Y.Y, Han, X, Gert, W, Wei, R, Liu, W.D, Bornscheuer, U.T.
Deposit date:2023-09-16
Release date:2024-09-18
Last modified:2025-04-23
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structure-Guided Engineering of a Versatile Urethanase Improves Its Polyurethane Depolymerization Activity.
Adv Sci, 12, 2025
6IYA
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BU of 6iya by Molmil
Structure of the DNA binding domain of antitoxin CopASO
Descriptor: Transcriptional regulator CopG family
Authors:Zhao, R, Li, F, Liu, L, Zhang, X.
Deposit date:2018-12-14
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and allosteric coupling of type II antitoxin CopASO.
Biochem.Biophys.Res.Commun., 514, 2019
7X8G
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BU of 7x8g by Molmil
Crystal structure of ENL T1(H116P) mutant YEATS domain in complex with histone H3 acetylation at K27
Descriptor: H3K27ac(24-27) peptide, Protein ENL
Authors:Li, Y, Peng, B, Li, H.
Deposit date:2022-03-12
Release date:2023-01-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7X8B
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BU of 7x8b by Molmil
Crystal structure of ENL T1 mutant YEATS domain in complex with histone H3 acetylation at K27
Descriptor: H3K27ac(24-27) peptide, Protein ENL
Authors:Li, Y, Peng, B, Li, H.
Deposit date:2022-03-11
Release date:2023-01-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7X8F
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BU of 7x8f by Molmil
Crystal structure of ENL T4 mutant YEATS domain in complex with histone H3 acetylation at K27
Descriptor: CHLORIDE ION, H3K27ac(24-27) peptide, Protein ENL
Authors:Li, Y, Peng, B, Li, H.
Deposit date:2022-03-12
Release date:2023-01-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
7X88
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BU of 7x88 by Molmil
Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27
Descriptor: CITRIC ACID, Histone H3K27ac(24-27) peptide, Protein ENL
Authors:Li, Y.Y, Li, H.T.
Deposit date:2022-03-11
Release date:2023-01-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
6INH
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BU of 6inh by Molmil
A glycosyltransferase with UDP and the substrate
Descriptor: 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, GLYCEROL, UDP-glycosyltransferase 76G1, ...
Authors:Zhu, X.
Deposit date:2018-10-25
Release date:2019-07-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
5H33
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BU of 5h33 by Molmil
Structural basis for dimerization of the death effector domains of Caspase-8
Descriptor: Caspase-8
Authors:Shen, C, Pei, J, Guo, X, Quan, J.
Deposit date:2016-10-20
Release date:2017-10-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.600138 Å)
Cite:Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5GLY
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BU of 5gly by Molmil
Crystal structure of a glycoside hydrolase in complex with cellotetrose from Thielavia terrestris NRRL 8126
Descriptor: Glycoside hydrolase family 45 protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Gao, J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
Deposit date:2016-07-12
Release date:2017-04-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GLX
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BU of 5glx by Molmil
Crystal structure of a glycoside hydrolase from Thielavia terrestris NRRL 8126
Descriptor: Glycoside hydrolase family 45 protein
Authors:Gao, J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
Deposit date:2016-07-12
Release date:2017-04-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GM5
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BU of 5gm5 by Molmil
Crystal structure of FI-CMCase from Aspergillus aculeatus F-50 in complex with cellobiose
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoglucanase-1, SULFATE ION, ...
Authors:Huang, J.W, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
Deposit date:2016-07-12
Release date:2017-05-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
6INI
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BU of 6ini by Molmil
a glycosyltransferase complex with UDP and the product
Descriptor: (8alpha,9beta,10alpha,13alpha)-13-{[beta-D-glucopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl]oxy}kaur-16-en-18-oic acid, 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zhu, X, Yang, T, Naismith, J.H.
Deposit date:2018-10-25
Release date:2019-07-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
7WIG
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BU of 7wig by Molmil
Cryo-EM structure of the L-054,264-bound human SSTR2-Gi1 complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Chen, L, Wang, W, Dong, Y, Shen, D, Guo, J, Qin, J, Zhang, H, Shen, Q, Zhang, Y, Mao, C.
Deposit date:2022-01-03
Release date:2022-06-01
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes.
Cell Res., 32, 2022
7WIC
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BU of 7wic by Molmil
Cryo-EM structure of the SS-14-bound human SSTR2-Gi1 complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Chen, L, Wang, W, Dong, Y, Shen, D, Guo, J, Qin, J, Zhang, H, Shen, Q, Zhang, Y, Mao, C.
Deposit date:2022-01-03
Release date:2022-06-01
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes.
Cell Res., 32, 2022
6JJS
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BU of 6jjs by Molmil
Crystal structure of an enzyme from Penicillium herquei in condition2
Descriptor: ACETATE ION, PhnH
Authors:Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
Deposit date:2019-02-26
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
6JJT
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BU of 6jjt by Molmil
Crystal structure of an enzyme from Penicillium herquei in condition1
Descriptor: CITRIC ACID, DI(HYDROXYETHYL)ETHER, PhnH
Authors:Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
Deposit date:2019-02-26
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
6ING
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BU of 6ing by Molmil
A complex structure of H25A mutant of glycosyltransferase with UDP
Descriptor: GLYCEROL, UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
Authors:Zhu, X, Naismith, J.H.
Deposit date:2018-10-25
Release date:2019-07-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
4RSE
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BU of 4rse by Molmil
Crystal structure of RPE65 in complex with MB-001 and palmitate
Descriptor: (1R)-3-amino-1-{3-[(2,6,6-trimethylcyclohex-1-en-1-yl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Shi, W, Palczewski, K.
Deposit date:2014-11-07
Release date:2015-04-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
2YPT
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BU of 2ypt by Molmil
Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A
Descriptor: CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
Authors:Pike, A.C.W, Dong, Y.Y, Quigley, A, Dong, L, Savitsky, P, Cooper, C.D.O, Chaikuad, A, Goubin, S, Shrestha, L, Li, Q, Mukhopadhyay, S, Yang, J, Xia, X, Shintre, C.A, Barr, A.J, Berridge, G, Chalk, R, Bray, J.E, von Delft, F, Bullock, A, Bountra, C, Arrowsmith, C.H, Edwards, A, Burgess-Brown, N, Carpenter, E.P.
Deposit date:2012-11-01
Release date:2012-12-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
4RSC
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BU of 4rsc by Molmil
Crystal structure of RPE65 in complex with emixustat and palmitate
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Shi, W, Palczewski, K.
Deposit date:2014-11-07
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
6INF
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BU of 6inf by Molmil
a glycosyltransferase complex with UDP
Descriptor: UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
Authors:Zhu, X, Yang, T, Naismith, J.H.
Deposit date:2018-10-25
Release date:2019-07-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
4HLR
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BU of 4hlr by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: Gp41, HEXANE-1,6-DIOL
Authors:Liu, J, Lu, M.
Deposit date:2012-10-17
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
8XGC
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BU of 8xgc by Molmil
Structure of yeast replisome associated with FACT and histone hexamer, Composite map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
Authors:Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y.
Deposit date:2023-12-15
Release date:2024-02-14
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Parental histone transfer caught at the replication fork.
Nature, 627, 2024
7E74
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BU of 7e74 by Molmil
Crystal structure of ENL YEATS domain T3 mutant in complex with histone H3 acetylation at K27
Descriptor: ALA-ALA-ARG-ALY, Protein ENL
Authors:Li, Y, Li, H.
Deposit date:2021-02-25
Release date:2021-07-07
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022

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