4RPY
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4RZR
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![BU of 4rzr by Molmil](/molmil-images/mine/4rzr) | Bypass of a bulky adduct dG1,8 by DPO4 | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Vyas, R, Suo, Z. | Deposit date: | 2014-12-23 | Release date: | 2015-09-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase. J.Am.Chem.Soc., 137, 2015
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5TB8
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5U2T
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5U2S
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5U2R
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![BU of 5u2r by Molmil](/molmil-images/mine/5u2r) | |
5VRX
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![BU of 5vrx by Molmil](/molmil-images/mine/5vrx) | |
5VS0
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![BU of 5vs0 by Molmil](/molmil-images/mine/5vs0) | Human DNA polymerase beta 8-oxoG:dC extension with dTTP after 80 s | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*CP*T)-3'), ... | Authors: | Reed, A.J, Suo, Z. | Deposit date: | 2017-05-11 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
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5VRZ
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![BU of 5vrz by Molmil](/molmil-images/mine/5vrz) | Human DNA polymerase beta 8-oxoG:dC extension with dTTP after 60 s | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*CP*T)-3'), ... | Authors: | Reed, A.J, Suo, Z. | Deposit date: | 2017-05-11 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
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5VS1
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5VS3
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![BU of 5vs3 by Molmil](/molmil-images/mine/5vs3) | Human DNA polymerase beta 8-oxoG:dA extension with dTTP after 90 s | Descriptor: | ACETATE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*AP*T)-3'), ... | Authors: | Reed, A.J, Suo, Z. | Deposit date: | 2017-05-11 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
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5VRY
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![BU of 5vry by Molmil](/molmil-images/mine/5vry) | Human DNA polymerase beta 8-oxoG:dC extension with dTTP after 20 s | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*CP*T)-3'), ... | Authors: | Reed, A.J, Suo, Z. | Deposit date: | 2017-05-11 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
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5VS2
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5VRW
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5VS4
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![BU of 5vs4 by Molmil](/molmil-images/mine/5vs4) | Human DNA polymerase beta 8-oxoG:dA extension with dTTP after 120 s | Descriptor: | ACETATE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*AP*T)-3'), ... | Authors: | Reed, A.J, Suo, Z. | Deposit date: | 2017-05-11 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
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5TBC
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2IMW
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![BU of 2imw by Molmil](/molmil-images/mine/2imw) | Mechanism of Template-Independent Nucleotide Incorporation Catalyzed by a Template-Dependent DNA Polymerase | Descriptor: | 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', ... | Authors: | Ling, H, Yang, W. | Deposit date: | 2006-10-05 | Release date: | 2007-01-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase. J.Mol.Biol., 365, 2007
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5JUM
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![BU of 5jum by Molmil](/molmil-images/mine/5jum) | Crystal Structure of Human DNA Polymerase Eta Inserting dCTP Opposite N-(2'-deoxyguanosin-8- yl)-3-aminobenzanthrone (C8-dG-ABA) | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | Authors: | Patra, A, Politica, D.A, Stone, M.P, Egli, M. | Deposit date: | 2016-05-10 | Release date: | 2016-09-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase eta. Chembiochem, 17, 2016
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2RDJ
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2RDI
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![BU of 2rdi by Molmil](/molmil-images/mine/2rdi) | |
3PR5
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![BU of 3pr5 by Molmil](/molmil-images/mine/3pr5) | Dpo4 Y12A mutant incorporating ADP opposite template dT | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*C)-3'), ... | Authors: | Kirouac, K.N, Ling, H. | Deposit date: | 2010-11-29 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase. J.Mol.Biol., 407, 2011
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3M9O
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3M9N
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3M9M
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6UIS
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![BU of 6uis by Molmil](/molmil-images/mine/6uis) | HIV-1 M184V reverse transcriptase-DNA complex with dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Primer DNA, ... | Authors: | Lansdon, E.B. | Deposit date: | 2019-10-01 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.74833822 Å) | Cite: | Elucidating molecular interactions ofL-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Commun Biol, 2, 2019
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