4RZR

Bypass of a bulky adduct dG1,8 by DPO4

Summary for 4RZR

DescriptorDNA polymerase IV, DNA (5'-D(*TP*TP*GP*C*(2JV)P*GP*AP*CP*TP*GP*GP*TP*AP*TP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*AP*TP*AP*CP*CP*AP*GP*TP*C)-3'), ... (9 entities in total)
Functional Keywordsdpo4, dbh, polymerase, transferase-dna complex, transferase/dna
Biological sourceSulfolobus solfataricus
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Cellular locationCytoplasm  Q97W02
Total number of polymer chains6
Total molecular weight100928.42
Authors
Vyas, R.,Suo, Z. (deposition date: 2014-12-23, release date: 2015-09-16, Last modification date: 2015-10-07)
Primary citation
Vyas, R.,Efthimiopoulos, G.,Tokarsky, E.J.,Malik, C.K.,Basu, A.K.,Suo, Z.
Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase.
J.Am.Chem.Soc., 137:12131-12142, 2015
PubMed: 26327169 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.5b08027
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25030.1%0.8%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution