4RZR

Bypass of a bulky adduct dG1,8 by DPO4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0009432	biological_process	SOS response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0003677	molecular_function	DNA binding
D	0003684	molecular_function	damaged DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006281	biological_process	DNA repair
D	0006974	biological_process	DNA damage response
D	0009432	biological_process	SOS response
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0042276	biological_process	error-prone translesion synthesis
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	ASP7
A	ASP105
A	GLU106
A	CA402
A	HOH502
A	HOH503

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	CA401
A	HOH501
A	HOH574
A	ASP7
A	PHE8
A	ASP105

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 403

Chain	Residue
A	ALA181
A	ILE186
A	HOH508
A	HOH522
C	HOH101

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TRS B 101

Chain	Residue
A	ARG332
B	2JV5
B	DG6
B	HOH208

---

site_id	AC5
Number of Residues	19
Details	BINDING SITE FOR RESIDUE DCP D 401

Chain	Residue
D	ASP7
D	PHE8
D	ASP9
D	TYR10
D	PHE11
D	TYR12
D	ALA44
D	THR45
D	TYR48
D	ARG51
D	ASP105
D	LYS159
D	CA402
D	CA403
D	HOH502
D	HOH523
D	HOH561
E	DG3
E	2JV5

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 402

Chain	Residue
D	ASP7
D	PHE8
D	ASP105
D	DCP401
D	CA403

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA D 403

Chain	Residue
D	ASP7
D	ASP105
D	GLU106
D	DCP401
D	CA402
D	HOH502
D	HOH503

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA D 404

Chain	Residue
D	ALA181
D	ILE186
D	HOH506
F	HOH101

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 405

Chain	Residue
D	VAL80
D	GLN83
D	VAL84
D	ARG87

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 406

Chain	Residue
D	GLU100
D	LYS148
D	TYR233
D	ARG240
D	HOH543

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE:

Chain	Residue	Details
A	GLU106
D	GLU106

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ASP7
A	ASP105
D	ASP7
D	ASP105

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Substrate discrimination

Chain	Residue	Details
A	TYR12
D	TYR12

---