5JUM
Crystal Structure of Human DNA Polymerase Eta Inserting dCTP Opposite N-(2'-deoxyguanosin-8- yl)-3-aminobenzanthrone (C8-dG-ABA)
Summary for 5JUM
Entry DOI | 10.2210/pdb5jum/pdb |
Related | 4O3N |
Descriptor | DNA polymerase eta, DNA (5'-D(*C*AP*TP*(4E9)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total) |
Functional Keywords | environmental carcinogen, catalytic domain, protein, dna, dna damage, dna-directed dna polymerase, guanosine triphosphate, y-family polymerase, trans-lesion synthesis (tls), polymerase eta, dna binding, 3-nitrobenzanthrone, n-(2'-deoxyguanosin-8- yl)-3-aminobenzanthrone (c8-dg-aba)., transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 55681.49 |
Authors | Patra, A.,Politica, D.A.,Stone, M.P.,Egli, M. (deposition date: 2016-05-10, release date: 2016-09-07, Last modification date: 2023-09-27) |
Primary citation | Patra, A.,Politica, D.A.,Chatterjee, A.,Tokarsky, E.J.,Suo, Z.,Basu, A.K.,Stone, M.P.,Egli, M. Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase eta. Chembiochem, 17:2033-2037, 2016 Cited by PubMed: 27556902DOI: 10.1002/cbic.201600420 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)