3M9O

Crystal Structure of Dpo4 in complex with DNA containing the major cisplatin lesion

Summary for 3M9O

• Entry DOI: 10.2210/pdb3m9o/pdb
• Related: 3M9M 3M9N
• Descriptor: DNA polymerase IV, DNA (5'-D(*GP*GP*GP*AP*AP*GP*GP*AP*AP*AP*GP*CP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... (7 entities in total)
• Functional Keywords: dpo4, translesion dna synthesis, tls, cisplatin, y-family dna polymerase, protein-dna complex, dna, dna damage, dna repair, dna replication, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, transferase, transferase-dna complex, transferase/dna
• Biological source: Sulfolobus solfataricus; More
• Cellular location: Cytoplasm : Q97W02
• Total number of polymer chains: 3
• Total formula weight: 50645.53

Authors

Wong, J.H.Y.,Ling, H. (deposition date: 2010-03-22, release date: 2010-06-16, Last modification date: 2024-03-13)

• Primary citation: Wong, J.H.,Brown, J.A.,Suo, Z.,Blum, P.,Nohmi, T.,Ling, H.; Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4.; Embo J., 29:2059-2069, 2010; PubMed: 20512114; DOI: 10.1038/emboj.2010.101

Experimental method

X-RAY DIFFRACTION (2 Å)