8DRU
| Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence | Descriptor: | DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp7-nsp8 (C7) cut site, PENTAETHYLENE GLYCOL, ... | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
8DRV
| Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp8-nsp9 (C8) cut site sequence | Descriptor: | Fusion protein of 3C-like proteinase nsp5 and nsp8-nsp9 (C8) cut site, PENTAETHYLENE GLYCOL | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
8DRY
| Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp12-nsp13 (C12) cut site sequence | Descriptor: | DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp12-nsp13 (C12) cut site | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
8DS0
| Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp14-nsp15 (C14) cut site sequence (form 2) | Descriptor: | 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
8DRZ
| Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp13-nsp14 (C13) cut site sequence | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
8DS2
| Structure of SARS-CoV-2 Mpro in complex with the nsp13-nsp14 (C13) cut site sequence (form 2) | Descriptor: | 3C-like proteinase nsp5, GLYCEROL, SODIUM ION | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
8DS1
| Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence | Descriptor: | 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, SODIUM ION | Authors: | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2022-07-21 | Release date: | 2022-09-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13, 2022
|
|
3BAH
| |
3BAO
| |
3BAV
| |
3BB2
| |
2AQZ
| Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant | Descriptor: | Heparin-binding growth factor 1, SULFATE ION | Authors: | Lee, J, Blaber, M. | Deposit date: | 2005-08-18 | Release date: | 2006-02-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins, 62, 2006
|
|
2VLG
| KinA PAS-A domain, homodimer | Descriptor: | ACETATE ION, CHLORIDE ION, SPORULATION KINASE A | Authors: | Lee, J, Tomchick, D.R, Brautigam, C.A, Machius, M, Kort, R, Hellingwerf, K.J, Gardner, K.H. | Deposit date: | 2008-01-14 | Release date: | 2008-03-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Changes at the Kina Pas-A Dimerization Interface Influence Histidine Kinase Function. Biochemistry, 47, 2008
|
|
2B02
| Crystal Structure of ARNT PAS-B Domain | Descriptor: | Aryl hydrocarbon receptor nuclear translocator | Authors: | Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G. | Deposit date: | 2005-09-12 | Release date: | 2006-10-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain To be Published
|
|
2QQS
| |
1YTO
| Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | Authors: | Lee, J, Blaber, M. | Deposit date: | 2005-02-10 | Release date: | 2006-01-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins, 62, 2006
|
|
1Z4S
| |
4QXL
| Crystal Structure of FLHE | Descriptor: | Flagellar protein flhE | Authors: | Lee, J, Monzingo, A.F, Keatinge-Clay, A.T, Harshey, R.M. | Deposit date: | 2014-07-21 | Release date: | 2015-01-14 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.512 Å) | Cite: | Structure of Salmonella FlhE, Conserved Member of a Flagellar Type III Secretion Operon. J.Mol.Biol., 427, 2015
|
|
3HL4
| Crystal structure of a mammalian CTP:phosphocholine cytidylyltransferase with CDP-choline | Descriptor: | Choline-phosphate cytidylyltransferase A, FORMIC ACID, GLYCEROL, ... | Authors: | Lee, J, Paetzel, M, Cornell, R.B. | Deposit date: | 2009-05-26 | Release date: | 2009-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a mammalian CTP: Phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyl-transferase fold J.Biol.Chem., 284, 2009
|
|
1Z2V
| |
7JP1
| |
7JOY
| |
7KHP
| Acyl-enzyme intermediate structure of SARS-CoV-2 Mpro in complex with its C-terminal autoprocessing sequence. | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Lee, J, Worrall, L.J, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2020-10-21 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun, 11, 2020
|
|
3EQA
| Catalytic domain of glucoamylase from aspergillus niger complexed with tris and glycerol | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Glucoamylase, ... | Authors: | Lee, J, Paetzel, M. | Deposit date: | 2008-09-30 | Release date: | 2009-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the catalytic domain of glucoamylase from Aspergillus niger. Acta Crystallogr.,Sect.F, 67, 2011
|
|
3O4C
| |