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2RKJ
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BU of 2rkj by Molmil
Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA
Descriptor: RNA (238-MER), RNA (5'-R(P*GP*CP*UP*U)-3'), Tyrosyl-tRNA synthetase
Authors:Paukstelis, P.J, Chen, J.-H, Chase, E, Lambowitz, A.M, Golden, B.L.
Deposit date:2007-10-16
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA.
Nature, 451, 2008
3I5Y
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BU of 3i5y by Molmil
Structure of Mss116p bound to ssRNA containing a single 5-BrU and AMP-PNP
Descriptor: 5'-R(*UP*UP*UP*(5BU)P*UP*UP*UP*UP*UP*U)-3', ATP-dependent RNA helicase MSS116, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
3I61
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BU of 3i61 by Molmil
Structure of Mss116p bound to ssRNA and ADP-Beryllium Fluoride
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
3I62
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BU of 3i62 by Molmil
Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
4OBC
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BU of 4obc by Molmil
Crystal structure of HCV polymerase NS5b genotype 2a JFH-1 isolate with the S15G, C223H, V321I resistance mutations against the guanosine analog GS-0938 (PSI-3529238)
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Edwards, T.E, Abendroth, J, Appleby, T.C.
Deposit date:2014-01-07
Release date:2014-09-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance.
Antimicrob.Agents Chemother., 58, 2014
8GIH
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BU of 8gih by Molmil
Structure of Hepatitis B Virus Capsid Y132A mutant in complex with Compound 24
Descriptor: (6S,8R)-N-(3-bromo-4-fluorophenyl)-8-fluoro-10-methyl-11-oxo-1,3,4,7,8,9,10,11-octahydro-2H-pyrido[4',3':3,4]pyrazolo[1,5-a][1,4]diazepine-2-carboxamide, CHLORIDE ION, Capsid protein
Authors:Shaffer, P.L.
Deposit date:2023-03-14
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Diazepinone HBV capsid assembly modulators.
Bioorg Med Chem Lett, 72, 2022
5E0I
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BU of 5e0i by Molmil
Crystal structure of the HBV capsid Y132A mutant (VCID 8772) in complex with NVR10-001E2 at 1.95A resolution
Descriptor: Capsid protein, methyl 4-(2-bromo-4-fluorophenyl)-6-(morpholin-4-ylmethyl)-2-(1,3-thiazol-2-yl)pyrimidine-5-carboxylate
Authors:Lukacs, C.M, Abendroth, J, Klumpp, K.
Deposit date:2015-09-28
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:High-resolution crystal structure of a hepatitis B virus replication inhibitor bound to the viral core protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
3XIM
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BU of 3xim by Molmil
ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS
Descriptor: COBALT (II) ION, D-XYLOSE ISOMERASE, sorbitol
Authors:Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J.
Deposit date:1991-05-29
Release date:1993-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Arginine residues as stabilizing elements in proteins.
Biochemistry, 31, 1992
4E7A
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BU of 4e7a by Molmil
Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin deletion bound to primer-template RNA with a 2',3'-ddC
Descriptor: 5'-R(*CP*AP*UP*GP*GP*C)-D(P*(DOC))-3', RNA-directed RNA polymerase
Authors:Edwards, T.E, Mosley, R.T.
Deposit date:2012-03-16
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of hepatitis C virus polymerase in complex with primer-template RNA.
J.Virol., 86, 2012
4E76
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BU of 4e76 by Molmil
Apo crystal structure of HCV NS5B genotype 2A JFH-1 isolate with beta hairpin loop deletion
Descriptor: 1,2-ETHANEDIOL, RNA-directed RNA polymerase, SULFATE ION
Authors:Edwards, T.E, Mosley, R.T.
Deposit date:2012-03-16
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of hepatitis C virus polymerase in complex with primer-template RNA.
J.Virol., 86, 2012
4E78
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BU of 4e78 by Molmil
Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin loop deletion bound to primer-template RNA with 3'-dG
Descriptor: 5'-R(*U*AP*CP*CP*GP*(GDO))-3', PROTEIN (RNA-directed RNA polymerase)
Authors:Edwards, T.E, Mosley, R.T.
Deposit date:2012-03-16
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of hepatitis C virus polymerase in complex with primer-template RNA.
J.Virol., 86, 2012
5OLJ
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BU of 5olj by Molmil
Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4
Descriptor: Dipeptidyl peptidase IV, GLYCEROL
Authors:Fulop, V.
Deposit date:2017-07-27
Release date:2017-09-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling.
Eur J Med Chem, 139, 2017
5XIN
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BU of 5xin by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE, D-xylose, MAGNESIUM ION
Authors:Janin, J.
Deposit date:1992-04-06
Release date:1993-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
5XIM
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BU of 5xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE, MAGNESIUM ION, sorbitol
Authors:Janin, J.
Deposit date:1992-03-30
Release date:1993-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
8XIM
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BU of 8xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE, D-xylose, MAGNESIUM ION
Authors:Janin, J.
Deposit date:1992-04-01
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
9XIM
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BU of 9xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE, D-xylose, MANGANESE (II) ION
Authors:Janin, J.
Deposit date:1992-04-03
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
7XIM
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BU of 7xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE
Authors:Janin, J.
Deposit date:1992-04-03
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
4XIM
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BU of 4xim by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: COBALT (II) ION, D-XYLOSE ISOMERASE
Authors:Janin, J.
Deposit date:1992-03-11
Release date:1993-07-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
1XIN
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BU of 1xin by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE, MAGNESIUM ION, Xylitol
Authors:Janin, J.
Deposit date:1992-04-06
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
1XIM
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BU of 1xim by Molmil
ARGININE RESIDUES AS STABILIZING ELEMENTS IN PROTEINS
Descriptor: COBALT (II) ION, D-XYLOSE ISOMERASE, Xylitol
Authors:Mrabet, N.T, Van Denbroek, A, Van Den Brande, I, Stanssens, P, Laroche, Y, Lambeir, A.-M, Matthyssens, G, Jenkins, J, Chiadmi, M, Vantilbeurgh, H, Rey, F, Janin, J, Quax, W.J, Lasters, I, Demaeyer, M, Wodak, S.J.
Deposit date:1991-05-29
Release date:1993-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Arginine residues as stabilizing elements in proteins.
Biochemistry, 31, 1992
6TIM
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BU of 6tim by Molmil
THE ADAPTABILITY OF THE ACTIVE SITE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AS OBSERVED IN THE CRYSTAL STRUCTURES OF THREE DIFFERENT COMPLEXES
Descriptor: SN-GLYCEROL-3-PHOSPHATE, TRIOSEPHOSPHATE ISOMERASE
Authors:Noble, M.E.M, Wierenga, R.K, Hol, W.G.J.
Deposit date:1991-04-23
Release date:1992-10-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
2XIN
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BU of 2xin by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: COBALT (II) ION, D-XYLOSE ISOMERASE, sorbitol
Authors:Janin, J.
Deposit date:1992-04-06
Release date:1993-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
3XIN
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BU of 3xin by Molmil
PROTEIN ENGINEERING OF XYLOSE (GLUCOSE) ISOMERASE FROM ACTINOPLANES MISSOURIENSIS. 1. CRYSTALLOGRAPHY AND SITE-DIRECTED MUTAGENESIS OF METAL BINDING SITES
Descriptor: D-XYLOSE ISOMERASE
Authors:Janin, J.
Deposit date:1992-04-06
Release date:1993-07-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Biochemistry, 31, 1992
1AMK
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BU of 1amk by Molmil
LEISHMANIA MEXICANA TRIOSE PHOSPHATE ISOMERASE
Descriptor: 2-PHOSPHOGLYCOLIC ACID, TRIOSE PHOSPHATE ISOMERASE
Authors:Williams, J.C, Wierenga, R.
Deposit date:1997-06-17
Release date:1997-12-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power.
Protein Eng., 12, 1999
4DB2
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BU of 4db2 by Molmil
Mss116p DEAD-box helicase domain 2 bound to an RNA duplex
Descriptor: 5'-R(*GP*GP*GP*CP*GP*GP*GP*CP*CP*CP*GP*CP*CP*C)-3', ATP-dependent RNA helicase MSS116, mitochondrial
Authors:Mallam, A.L, Del Campo, M, Gilman, B.D, Sidote, D.J, Lambowitz, A.
Deposit date:2012-01-13
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p.
Nature, 490, 2012

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