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4EEF
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BU of 4eef by Molmil
Crystal structure of the designed inhibitor protein F-HB80.4 in complex with the 1918 influenza virus hemagglutinin.
Descriptor: F-HB80.4, DESIGNED HEMAGGLUTININ BINDING PROTEIN, Hemagglutinin HA1 chain, ...
Authors:Dreyfus, C, Wilson, I.A.
Deposit date:2012-03-28
Release date:2012-06-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing.
Nat.Biotechnol., 30, 2012
7PVD
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BU of 7pvd by Molmil
Structure of the membrane soluble spike complex from the Lassa virus in a C1-symmetric map focused on the ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G2, ...
Authors:Diskin, R, Katz, M.
Deposit date:2021-10-02
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure and receptor recognition by the Lassa virus spike complex.
Nature, 603, 2022
7PUY
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BU of 7puy by Molmil
Structure of the membrane soluble spike complex from the Lassa virus in a C3-symmetric map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G2, ...
Authors:Diskin, R, Katz, M.
Deposit date:2021-10-01
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure and receptor recognition by the Lassa virus spike complex.
Nature, 603, 2022
8CY8
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BU of 8cy8 by Molmil
apo form Cryo-EM structure of Campylobacter jejune ketol-acid reductoisommerase crosslinked by Glutaraldehyde
Descriptor: Ketol-acid reductoisomerase (NADP(+)), PENTANEDIAL
Authors:Zheng, S, Guddat, L.W.
Deposit date:2022-05-23
Release date:2023-02-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals
Appl Biosci, 2022
6WA0
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BU of 6wa0 by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
Descriptor: De novo designed receptor transmembrane domain proMP C3.1
Authors:Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
Deposit date:2020-03-24
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.484 Å)
Cite:De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
6W9Y
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BU of 6w9y by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain proMP 1.2
Authors:Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
Deposit date:2020-03-24
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
6W9Z
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BU of 6w9z by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain ProMP C2.1
Authors:Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
Deposit date:2020-03-24
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
3U43
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BU of 3u43 by Molmil
Crystal structure of the colicin E2 DNase-Im2 complex
Descriptor: CALCIUM ION, Colicin-E2, Colicin-E2 immunity protein, ...
Authors:Wojdyla, J.A, Kleanthous, C.
Deposit date:2011-10-07
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure of the Ultra-High-Affinity Colicin E2 DNase-Im2 Complex.
J.Mol.Biol., 417, 2012
3VB8
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BU of 3vb8 by Molmil
Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43
Descriptor: Engineered protein, SULFATE ION
Authors:Seetharaman, J, Su, M, Procko, E, Baker, D, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-12-31
Release date:2012-06-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Computational design of a protein-based enzyme inhibitor.
J.Mol.Biol., 425, 2013
6XUD
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BU of 6xud by Molmil
Apo Ab 1116NS19.9
Descriptor: Heavy chain, Light chain
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-19
Release date:2021-01-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6XUL
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BU of 6xul by Molmil
Apo Ab 5b1
Descriptor: Heavy chain, Light chain
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-20
Release date:2021-02-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6YBH
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BU of 6ybh by Molmil
Deoxyribonucleoside Kinase
Descriptor: Deoxynucleoside kinase, GLYCEROL, Pyrrolo-dC, ...
Authors:Allouche-Arnon, H, Bar-Shir, A, Dym, O.
Deposit date:2020-03-17
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.
Nat.Biotechnol., 40, 2022
6XUK
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BU of 6xuk by Molmil
AbLIFT design 15 of Ab 1116NS19.9
Descriptor: GLYCEROL, Heavy chain, Light chain, ...
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-20
Release date:2021-02-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
5D96
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BU of 5d96 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
Descriptor: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
Authors:Fass, D, Grossman, I.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D93
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BU of 5d93 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
Descriptor: Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Sulfhydryl oxidase 1
Authors:Grossman, I, Fass, D.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D8I
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BU of 5d8i by Molmil
Engineering the Species-Specificity of an Inhibitory Antibody Targeting a Modulator of Tumor Stroma
Descriptor: Sulfhydryl oxidase 1
Authors:Grossman, I, Fass, D.
Deposit date:2015-08-17
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
6GVS
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BU of 6gvs by Molmil
Engineered glycolyl-CoA reductase comprising 8 mutations with bound NADP+
Descriptor: Aldehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION
Authors:Zarzycki, J, Trudeau, D, Scheffen, M, Erb, T.J, Tawfik, D.S.
Deposit date:2018-06-21
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.579 Å)
Cite:Design and in vitro realization of carbon-conserving photorespiration.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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