5IU1
 
 | | N-terminal PAS domain homodimer of PpANR MAP3K from Physcomitrella patens. | | Descriptor: | CTR1-like protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Stevenson, R.R, Trinh, C.H, Edwards, T.A, Cuming, A.C. | | Deposit date: | 2016-03-17 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Genetic Analysis of Physcomitrella patens Identifies ABSCISIC ACID NON-RESPONSIVE, a Regulator of ABA Responses Unique to Basal Land Plants and Required for Desiccation Tolerance.
Plant Cell, 28, 2016
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5EQL
 | | Isoform-specific inhibition of SUMO-dependent protein-protein interactions | | Descriptor: | SUMO-Affirmer-S2D5, Small ubiquitin-related modifier 2 | | Authors: | Hughes, D.J, Tiede, C, Hall, N, Tang, A.A.S, Trinh, C.H, Zajac, K, Mandal, U, Howell, G, Edwards, T.A, McPherson, M.J, Tomlinson, D.C, Whitehouse, A. | | Deposit date: | 2015-11-13 | | Release date: | 2016-11-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.
Sci Signal, 10, 2017
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8C4H
 | | CryoEM structure of the Hendra henipavirus nucleocapsid sauronoid assembly multimer | | Descriptor: | Nucleocapsid, RNA (84-MER) | | Authors: | Passchier, T.C, Maskell, D.P, Edwards, T.A, Barr, J.N. | | Deposit date: | 2023-01-04 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.485 Å) | | Cite: | The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures.
Sci Rep, 14, 2024
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5ELJ
 | | Isoform-specific inhibition of SUMO-dependent protein-protein interactions | | Descriptor: | SUMO-Affirmer-S2D5, Small ubiquitin-related modifier 1 | | Authors: | Hughes, D.J, Tiede, C, Hall, N, Tang, A.A.S, Trinh, C.H, Zajac, K, Mandal, U, Howell, G, Edwards, T.A, McPherson, M.J, Tomlinson, D.C, Whitehouse, A. | | Deposit date: | 2015-11-04 | | Release date: | 2016-11-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.983 Å) | | Cite: | Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.
Sci Signal, 10, 2017
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5ELU
 | | Isoform-specific inhibition of SUMO-dependent protein-protein interactions | | Descriptor: | SULFATE ION, SUMO-Affirmer-S2B3, Small ubiquitin-related modifier 2 | | Authors: | Hughes, D.J, Tiede, C, Hall, N, Tang, A.A.S, Trinh, C.H, Zajac, K, Mandal, U, Howell, G, Edwards, T.A, McPherson, M.J, Tomlinson, D.C, Whitehouse, A. | | Deposit date: | 2015-11-05 | | Release date: | 2016-11-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.
Sci Signal, 10, 2017
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4C3E
 | | HRSV M2-1 mutant S58D S61D, P21 crystal | | Descriptor: | MATRIX M2-1, ZINC ION | | Authors: | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | | Deposit date: | 2013-08-22 | | Release date: | 2014-01-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4AKL
 | | Structure of the Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Protein | | Descriptor: | NUCLEOCAPSID, TRIETHYLENE GLYCOL | | Authors: | Carter, S.D, Walter, C.T, Surtees, R, Bergeron, E, Ariza, A, Albarino, C.G, Nichol, S.T, Hiscox, J.A, Edwards, T.A, Barr, J.N. | | Deposit date: | 2012-02-24 | | Release date: | 2012-08-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure, Function, and Evolution of the Crimean-Congo Hemorrhagic Fever Virus Nucleocapsid Protein.
J.Virol., 86, 2012
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4C3D
 | | HRSV M2-1, P422 crystal form | | Descriptor: | CADMIUM ION, MATRIX M2-1 | | Authors: | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | | Deposit date: | 2013-08-22 | | Release date: | 2014-01-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4C3B
 | | HRSV M2-1, P21 crystal form | | Descriptor: | MATRIX PROTEIN 2-1, ZINC ION | | Authors: | Tanner, S.J, Ariza, A, Richard, C.A, Wu, W, Trincao, J, Hiscox, J.A, Carroll, M.W, Silman, N.J, Eleouet, J.F, Edwards, T.A, Barr, J.N. | | Deposit date: | 2013-08-22 | | Release date: | 2014-01-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal Structure of the Essential Transcription Antiterminator M2-1 Protein of Human Respiratory Syncytial Virus and Implications of its Phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3ZL9
 | | Crystal structure of the nucleocapsid protein from Schmallenberg virus | | Descriptor: | NUCLEOCAPSID PROTEIN | | Authors: | Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. | | Deposit date: | 2013-01-29 | | Release date: | 2013-05-01 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization.
Nucleic Acids Res., 41, 2013
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3ZLA
 | | Crystal structure of the nucleocapsid protein from Bunyamwera virus bound to RNA | | Descriptor: | NUCLEOPROTEIN, RNA | | Authors: | Ariza, A, Tanner, S.J, Walter, C.T, Dent, K.C, Shepherd, D.A, Wu, W, Matthews, S.V, Hiscox, J.A, Green, T.J, Luo, M, Elliot, R.M, Ashcroft, A.E, Stonehouse, N.J, Ranson, N.A, Barr, J.N, Edwards, T.A. | | Deposit date: | 2013-01-29 | | Release date: | 2013-05-01 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Nucleocapsid Protein Structures from Orthobunyaviruses Reveal Insight Into Ribonucleoprotein Architecture and RNA Polymerization.
Nucleic Acids Res., 41, 2013
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3GVO
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3GVT
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7A00
 | | Crystal structure of Shank1 PDZ in complex with L6F mutant of the C-terminal hexapeptide from GKAP | | Descriptor: | L6F mutant of C-terminal hexapeptide from Guanylate kinase-associated protein, SH3 and multiple ankyrin repeat domains protein 1 | | Authors: | Zsofia, H, Hetherington, K, Fruzsina, H, Edwards, T.A, Wilson, A.J. | | Deposit date: | 2020-08-05 | | Release date: | 2021-07-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Query-guided protein-protein interaction inhibitor discovery.
Chem Sci, 12, 2021
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5A97
 | | Hazara virus nucleocapsid protain | | Descriptor: | NUCLEOCAPSID PROTEIN | | Authors: | Surtees, R, Ariza, A, Hewson, R, Barr, J.N, Edwards, T.A. | | Deposit date: | 2015-07-17 | | Release date: | 2016-01-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Crystal Structure of the Hazara Virus Nucleocapsid Protein.
Bmc Struct.Biol., 15, 2015
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5A38
 | | Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | | Descriptor: | ALPHA-ACTININ-2 | | Authors: | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | | Deposit date: | 2015-05-27 | | Release date: | 2016-06-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
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5A0O
 | | adhiron raised against p300 | | Descriptor: | ADHIRON | | Authors: | Kyle, H.F, Wickson, K.F, Stott, J, Burslem, G.M, Breeze, A.L, Tiede, C, Tomlinson, D.C, Warriner, S.L, Nelson, A, Wilson, A.J, Edwards, T.A. | | Deposit date: | 2015-04-21 | | Release date: | 2015-07-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Exploration of the Hif-1Alpha.P300 Interface Using Peptide and Adhiron Phage Display Technologies
Mol.Biosyst., 11, 2015
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5A37
 | | Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | | Descriptor: | HUMAN ALPHA-ACTININ-2 | | Authors: | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | | Deposit date: | 2015-05-27 | | Release date: | 2016-06-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
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5A4B
 | | Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | | Descriptor: | HUMAN ALPHA-ACTININ-2 | | Authors: | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | | Deposit date: | 2015-06-05 | | Release date: | 2016-06-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
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5A36
 | | Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. | | Descriptor: | ALPHA-ACTININ-2 | | Authors: | Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. | | Deposit date: | 2015-05-27 | | Release date: | 2016-06-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation.
Biochem.J., 473, 2016
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1SDO
 | | Crystal Structure of Restriction Endonuclease BstYI | | Descriptor: | BstYI | | Authors: | Townson, S.A, Samuelson, J.C, Vanamee, E.S, Edwards, T.A, Escalante, C.R, Xu, S.Y, Aggarwal, A.K. | | Deposit date: | 2004-02-13 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structure of BstYI at 1.85 A Resolution: A Thermophilic Restriction Endonuclease with Overlapping Specificities to BamHI and BglII
J.Mol.Biol., 338, 2004
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1S9H
 | | Crystal Structure of Adeno-associated virus Type 2 Rep40 | | Descriptor: | Rep 40 protein | | Authors: | James, J.A, Escalante, C.R, Yoon-Robarts, M, Edwards, T.A, Linden, R.M, Aggarwal, A.K. | | Deposit date: | 2004-02-04 | | Release date: | 2004-05-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of the SF3 Helicase from Adeno-Associated Virus Type 2
Structure, 11, 2003
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1T94
 | | Crystal structure of the catalytic core of human DNA polymerase kappa | | Descriptor: | polymerase (DNA directed) kappa | | Authors: | Uljon, S.N, Johnson, R.E, Edwards, T.A, Prakash, S, Prakash, L, Aggarwal, A.K. | | Deposit date: | 2004-05-14 | | Release date: | 2004-08-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the catalytic core of human DNA polymerase kappa.
STRUCTURE, 12, 2004
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2XS7
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2XSF
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