5C3F
Crystal structure of Mcl-1 bound to BID-MM
Summary for 5C3F
| Entry DOI | 10.2210/pdb5c3f/pdb |
| Descriptor | Induced myeloid leukemia cell differentiation protein Mcl-1, BID-MM, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | complex, bcl-2 family, bh3, stapled peptide, apoptosis |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Membrane ; Single-pass membrane protein : Q07820 |
| Total number of polymer chains | 2 |
| Total formula weight | 20576.46 |
| Authors | Miles, J.A.,Yeo, D.J.,Rowell, P.,Rodriguez-Marin, S.,Pask, C.M.,Warriner, S.L.,Edwards, T.A.,Wilson, A.J. (deposition date: 2015-06-17, release date: 2016-04-20, Last modification date: 2024-01-10) |
| Primary citation | Miles, J.A.,Yeo, D.J.,Rowell, P.,Rodriguez-Marin, S.,Pask, C.M.,Warriner, S.L.,Edwards, T.A.,Wilson, A.J. Hydrocarbon constrained peptides - understanding preorganisation and binding affinity. Chem Sci, 7:3694-3702, 2016 Cited by PubMed: 28970875DOI: 10.1039/c5sc04048e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.43 Å) |
Structure validation
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