Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0043065 | biological_process | positive regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ARG176 |
| A | ARG187 |
| A | HOH523 |
| A | HOH525 |
| A | HOH539 |
| A | HOH544 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residues NLE B 92 and NLE B 96 |
| Chain | Residue |
| B | LEU90 |
| B | ALA91 |
| B | VAL93 |
| B | GLY94 |
| B | ASP95 |
| B | NLE97 |
| B | ASP98 |
| B | ARG99 |
| B | SER100 |
| A | ASP256 |
| B | ARG88 |
| B | HIS89 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residues NLE B 96 and NLE B 97 |
| Chain | Residue |
| A | VAL216 |
| A | ASP256 |
| A | VAL265 |
| A | PHE319 |
| B | NLE92 |
| B | VAL93 |
| B | GLY94 |
| B | ASP95 |
| B | ASP98 |
| B | ARG99 |
| B | SER100 |
| B | ILE101 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 20 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA |
| Chain | Residue | Details |
| A | VAL253-ALA272 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV |
| Chain | Residue | Details |
| A | TRP305-VAL316 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN |
| Chain | Residue | Details |
| A | ALA209-ASN223 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Motif: {"description":"BH3"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Motif: {"description":"BH1"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Motif: {"description":"BH2"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"} |
