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3MWL
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BU of 3mwl by Molmil
Q28E mutant of HERA N-terminal RecA-like domain in complex with 8-OXOADENOSINE
Descriptor: 6-azanyl-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purin-8-one, Heat resistant RNA dependent ATPase, SULFATE ION
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2010-05-06
Release date:2011-03-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3MWJ
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BU of 3mwj by Molmil
Q28E mutant of HERA N-terminal RecA-like domain, apo form
Descriptor: Heat resistant RNA dependent ATPase, SULFATE ION
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2010-05-06
Release date:2011-03-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
3MWK
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BU of 3mwk by Molmil
Q28E mutant of HERA N-terminal RecA-like domain, complex with 8-oxo-AMP
Descriptor: Heat resistant RNA dependent ATPase, SULFATE ION, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2010-05-06
Release date:2011-03-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.
Biol.Chem., 392, 2011
7OQM
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BU of 7oqm by Molmil
Human OMPD-domain of UMPS in complex with substrate OMP at 1.05 Angstroms resolution, 20 minutes soaking
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Rindfleisch, S, Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2021-06-03
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OQN
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BU of 7oqn by Molmil
Human OMPD-domain of UMPS in complex with substrate OMP at 1.10 Angstroms resolution, 30 minutes soaking
Descriptor: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Rindfleisch, S, Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2021-06-03
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OQF
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BU of 7oqf by Molmil
Human OMPD-domain of UMPS in complex with OMP at 1.05 Angstrom resolution, 5 minutes soaking
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Rindfleisch, S, Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2021-06-03
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OQI
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BU of 7oqi by Molmil
Human OMPD-domain of UMPS in complex with substrate OMP at 1.15 Angstrom resolution, 10 minutes soaking
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Rindfleisch, S, Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2021-06-03
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OQK
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BU of 7oqk by Molmil
Human OMPD-domain of UMPS in complex with substrate OMP at 1.10 Angstroms resolution, 15 minutes soaking
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Rindfleisch, S, Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2021-06-03
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OUZ
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BU of 7ouz by Molmil
Human OMPD-domain of UMPS in complex with 6-hydroxy-UMP at 0.9 Angstroms resolution, crystal 1
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, PROLINE, ...
Authors:Rindfleisch, S, Tittmann, K.
Deposit date:2021-06-14
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OV0
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BU of 7ov0 by Molmil
Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in resting state at 0.95 Angstrom resolution
Descriptor: GLYCEROL, PROLINE, SULFATE ION, ...
Authors:Rindfleisch, S, Rabe von Pappenheim, F.
Deposit date:2021-06-14
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7OTU
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BU of 7otu by Molmil
Human OMPD-domain of UMPS in complex with 6-hydroxy-UMP at 0.95 Angstroms resolution, crystal 2
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Isoform 2 of Uridine 5'-monophosphate synthase
Authors:Rindfleisch, S, Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2021-06-10
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
7Q1H
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BU of 7q1h by Molmil
Variant D312N of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in complex with the substrate OMP at 1.31 Angstrom resolution
Descriptor: OROTIDINE-5'-MONOPHOSPHATE, PROLINE, SULFATE ION, ...
Authors:Rabe von Pappenheim, F, Kirck, L.L.
Deposit date:2021-10-20
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis
Nat Catal, 5, 2022
6ZWJ
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BU of 6zwj by Molmil
Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution
Descriptor: CITRIC ACID, GLYCEROL, Transaldolase
Authors:Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K.
Deposit date:2020-07-28
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWF
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BU of 6zwf by Molmil
Neisseria gonorrhoeae transaldolase
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ...
Authors:Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
Deposit date:2020-07-28
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZWH
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BU of 6zwh by Molmil
Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
Authors:Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K.
Deposit date:2020-07-28
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
6ZX4
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BU of 6zx4 by Molmil
Neisseria gonorrhoeae transaldolase
Descriptor: CITRIC ACID, GLYCEROL, Transaldolase
Authors:Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
Deposit date:2020-07-29
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
7B0L
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BU of 7b0l by Molmil
Neisseria gonorrhoeae transaldolase, low-dose inhouse
Descriptor: CITRIC ACID, Transaldolase
Authors:Rabe von Pappenheim, F, Wensien, M, Tittmann, K.
Deposit date:2020-11-20
Release date:2021-03-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
2QCL
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BU of 2qcl by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP
Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCC
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BU of 2qcc by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form
Descriptor: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCM
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BU of 2qcm by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP
Descriptor: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCG
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BU of 2qcg by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP
Descriptor: 5-BROMO-URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCH
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BU of 2qch by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCN
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BU of 2qcn by Molmil
Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP
Descriptor: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCD
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BU of 2qcd by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP
Descriptor: URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008
2QCF
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BU of 2qcf by Molmil
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
Descriptor: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase)
Authors:Wittmann, J, Rudolph, M.
Deposit date:2007-06-19
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
Structure, 16, 2008

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