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8GY4
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Crystal structure of Alongshan virus methyltransferase
Descriptor: Methyltransferase
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GY9
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BU of 8gy9 by Molmil
Crystal structure of Alongshan virus methyltransferase bound to S-adenosyl-L-methionine
Descriptor: Methyltransferase, S-ADENOSYLMETHIONINE
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
7EAN
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BU of 7ean by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7DK3
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BU of 7dk3 by Molmil
SARS-CoV-2 S trimer, S-open
Descriptor: Spike glycoprotein
Authors:Xu, C, Cong, Y.
Deposit date:2020-11-23
Release date:2020-12-16
Last modified:2021-02-17
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.
Sci Adv, 7, 2021
7DD2
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BU of 7dd2 by Molmil
S-3C1-F2 structure, two RBDs are up and one RBD is down, the two up RBD bind with a 3C1 fab.
Descriptor: Spike glycoprotein, The heavy chain of 3C1 fab, The light chain of 3C1 fab
Authors:Cong, Y, Liu, C.X.
Deposit date:2020-10-27
Release date:2020-12-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK4
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BU of 7dk4 by Molmil
S-2H2-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 2H2 Fab.
Descriptor: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab
Authors:Cong, Y, Wang, Y.F.
Deposit date:2020-11-23
Release date:2020-12-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7EAM
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BU of 7eam by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7DDN
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BU of 7ddn by Molmil
SARS-Cov2 S protein at open state
Descriptor: Spike glycoprotein
Authors:Cong, Y, Liu, C.X.
Deposit date:2020-10-29
Release date:2020-11-25
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DF4
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BU of 7df4 by Molmil
SARS-CoV-2 S-ACE2 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Cong, X, Yao, C.
Deposit date:2020-11-06
Release date:2020-12-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.
Sci Adv, 7, 2021
7DDD
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BU of 7ddd by Molmil
SARS-Cov2 S protein at close state
Descriptor: Spike glycoprotein
Authors:Cong, Y, Liu, C.X.
Deposit date:2020-10-28
Release date:2020-11-25
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DF3
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BU of 7df3 by Molmil
SARS-CoV-2 S trimer, S-closed
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Cong, X, Yao, C.
Deposit date:2020-11-06
Release date:2020-12-16
Last modified:2021-02-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.
Sci Adv, 7, 2021
7DCX
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BU of 7dcx by Molmil
S-3C1-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 3C1 fab.
Descriptor: Spike glycoprotein, The heavy chain of 3C1 fab that binds with the up RBD, The light chain of 3C1 fab
Authors:Cong, Y, Liu, C.X.
Deposit date:2020-10-27
Release date:2020-12-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK7
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BU of 7dk7 by Molmil
S-2H2-F3b structure, three RBDs are up and each RBD binds with a 2H2 Fab.
Descriptor: Spike glycoprotein, The heavy chain fragment of 2H2 Fab, The light chain fragment of 2H2 Fab
Authors:Cong, Y, Wang, Y.F.
Deposit date:2020-11-23
Release date:2020-12-02
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DCC
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BU of 7dcc by Molmil
S-3C1-F3b structure, all the three RBDs are in the up conformation and each of them associates with a 3C1 Fab
Descriptor: Spike glycoprotein, The heavy chain of 3C1 fab, The light chain of 3C1 fab
Authors:Cong, Y, Liu, C.X.
Deposit date:2020-10-24
Release date:2020-12-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK6
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BU of 7dk6 by Molmil
S-2H2-F2 structure, two RBDs are up and one RBD is down, each up RBD binds with a 2H2 Fab.
Descriptor: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab
Authors:Cong, Y, Wang, Y.F.
Deposit date:2020-11-23
Release date:2020-12-02
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DD8
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BU of 7dd8 by Molmil
S-3C1-F1 structure, one RBD is up and two RBDs are down, the up RBD binds with a 3C1 fab
Descriptor: Spike glycoprotein, The heavy chain of 3C1 fab, The light chain of 3C1 chain
Authors:Cong, Y, Liu, C.X.
Deposit date:2020-10-28
Release date:2020-12-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7DK5
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BU of 7dk5 by Molmil
S-2H2-F1 structure, one RBD is up and two RBDs are down, only up RBD binds with a 2H2 Fab
Descriptor: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab
Authors:Cong, Y, Wang, Y.F.
Deposit date:2020-11-23
Release date:2020-12-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
7V47
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BU of 7v47 by Molmil
Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V48
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BU of 7v48 by Molmil
Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V49
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BU of 7v49 by Molmil
Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
6A37
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BU of 6a37 by Molmil
X-ray structure of cyclohexanone monooxygenase from Acinetobacter calcoaceticus
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase
Authors:Zhang, Y, Yu, H.L, Xu, J.H.
Deposit date:2018-06-15
Release date:2019-03-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Engineering of Cyclohexanone Monooxygenase for the Enantioselective Synthesis of (S)-Omeprazole
Acs Sustain Chem Eng
8X7P
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BU of 8x7p by Molmil
CCA-bound E46K alpha-synuclein fibrils
Descriptor: Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate
Authors:Liu, K.E, Tao, Y.Q, Li, D, Liu, C.
Deposit date:2023-11-24
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
8X7R
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BU of 8x7r by Molmil
C05-03-bound E46K alpha-synuclein fibrils
Descriptor: 2-[(~{E})-4-[6-(methylamino)pyridin-3-yl]but-1-en-3-ynyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Liu, K.E, Tao, Y.Q, Li, D, Liu, C.
Deposit date:2023-11-24
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
8X7Q
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BU of 8x7q by Molmil
pFTAA-bound E46K alpha-synuclein fibrils
Descriptor: 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid, Alpha-synuclein
Authors:Liu, K.E, Tao, Y.Q, Li, D, Liu, C.
Deposit date:2023-11-24
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
8X7O
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BU of 8x7o by Molmil
PiB-bound E46K mutanted alpha-synuclein fibrils
Descriptor: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
Authors:Liu, K.E, Tao, Y.Q, Li, D, Liu, C.
Deposit date:2023-11-24
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024

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