8GY4
| Crystal structure of Alongshan virus methyltransferase | Descriptor: | Methyltransferase | Authors: | Chen, H, Lin, S, Lu, G.W. | Deposit date: | 2022-09-21 | Release date: | 2023-09-27 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses. Plos Pathog., 19, 2023
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8GY9
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7EAN
| immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ... | Authors: | Li, T.T, Gu, Y, Li, S.W. | Deposit date: | 2021-03-07 | Release date: | 2021-03-31 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants. Nat Commun, 12, 2021
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7DK3
| SARS-CoV-2 S trimer, S-open | Descriptor: | Spike glycoprotein | Authors: | Xu, C, Cong, Y. | Deposit date: | 2020-11-23 | Release date: | 2020-12-16 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM. Sci Adv, 7, 2021
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7DD2
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7DK4
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7EAM
| immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | Authors: | Li, T.T, Gu, Y, Li, S.W. | Deposit date: | 2021-03-07 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants. Nat Commun, 12, 2021
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7DDN
| SARS-Cov2 S protein at open state | Descriptor: | Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2020-10-29 | Release date: | 2020-11-25 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections. Nat Commun, 12, 2021
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7DF4
| SARS-CoV-2 S-ACE2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Cong, X, Yao, C. | Deposit date: | 2020-11-06 | Release date: | 2020-12-16 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM. Sci Adv, 7, 2021
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7DDD
| SARS-Cov2 S protein at close state | Descriptor: | Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2020-10-28 | Release date: | 2020-11-25 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections. Nat Commun, 12, 2021
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7DF3
| SARS-CoV-2 S trimer, S-closed | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Cong, X, Yao, C. | Deposit date: | 2020-11-06 | Release date: | 2020-12-16 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM. Sci Adv, 7, 2021
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7DCX
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7DK7
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7DCC
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7DK6
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7DD8
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7DK5
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7V47
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7V48
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7V49
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6A37
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8X7P
| CCA-bound E46K alpha-synuclein fibrils | Descriptor: | Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate | Authors: | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | Deposit date: | 2023-11-24 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
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8X7R
| C05-03-bound E46K alpha-synuclein fibrils | Descriptor: | 2-[(~{E})-4-[6-(methylamino)pyridin-3-yl]but-1-en-3-ynyl]-1,3-benzothiazol-6-ol, Alpha-synuclein | Authors: | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | Deposit date: | 2023-11-24 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
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8X7Q
| pFTAA-bound E46K alpha-synuclein fibrils | Descriptor: | 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid, Alpha-synuclein | Authors: | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | Deposit date: | 2023-11-24 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
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8X7O
| PiB-bound E46K mutanted alpha-synuclein fibrils | Descriptor: | 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein | Authors: | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | Deposit date: | 2023-11-24 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
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