8X7O

PiB-bound E46K mutanted alpha-synuclein fibrils

Summary for 8X7O

Entry DOI	10.2210/pdb8x7o/pdb
EMDB information	38105
Descriptor	Alpha-synuclein, 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol (2 entities in total)
Functional Keywords	amyloid fibril, complex, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	10
Total formula weight	147837.63
Authors	Liu, K.E.,Tao, Y.Q.,Li, D.,Liu, C. (deposition date: 2023-11-24, release date: 2024-09-11)
Primary citation	Liu, K.,Tao, Y.,Zhao, Q.,Xia, W.,Li, X.,Zhang, S.,Yao, Y.,Xiang, H.,Han, C.,Tan, L.,Sun, B.,Li, D.,Li, A.,Liu, C. Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121:e2321633121-e2321633121, 2024 Cited by PubMed: 39172784 DOI: 10.1073/pnas.2321633121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation