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6FEK
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BU of 6fek by Molmil
Oncogenic point mutation of RET receptor tyrosine kinase
Descriptor: ADENOSINE, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
Authors:McDonald, N.Q, Kohno, T.
Deposit date:2018-01-02
Release date:2018-02-28
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A secondary RET mutation in the activation loop conferring resistance to vandetanib.
Nat Commun, 9, 2018
1ISS
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BU of 1iss by Molmil
Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist
Descriptor: (S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE, Metabotropic Glutamate Receptor subtype 1
Authors:Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K.
Deposit date:2001-12-21
Release date:2002-03-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
1ISR
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BU of 1isr by Molmil
Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion
Descriptor: GADOLINIUM ATOM, GLUTAMIC ACID, Metabotropic Glutamate Receptor subtype 1
Authors:Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K.
Deposit date:2001-12-21
Release date:2002-03-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
1ODD
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BU of 1odd by Molmil
OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI
Descriptor: TRANSCRIPTIONAL REGULATORY PROTEIN OMPR
Authors:Kondou, H, Nakagawa, A, Tanaka, I.
Deposit date:1996-10-31
Release date:1997-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.
Nat.Struct.Biol., 4, 1997
7Y7E
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BU of 7y7e by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7G
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BU of 7y7g by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7H
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BU of 7y7h by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7D
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BU of 7y7d by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7C
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BU of 7y7c by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7F
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BU of 7y7f by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAC)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
Deposit date:2022-06-22
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7BVR
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BU of 7bvr by Molmil
DgpB-DgpC complex apo
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AP_endonuc_2 domain-containing protein, DgpB, ...
Authors:Mori, T, He, H, Abe, I.
Deposit date:2020-04-11
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.
Nat Commun, 12, 2021
7BVS
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BU of 7bvs by Molmil
DfgA-DfgB complex apo
Descriptor: DfgB, GLYCEROL, MANGANESE (II) ION, ...
Authors:Mori, T, He, H, Abe, I.
Deposit date:2020-04-11
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.
Nat Commun, 12, 2021
8IG0
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BU of 8ig0 by Molmil
Crystal structure of menin in complex with DS-1594b
Descriptor: (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol, DIMETHYL SULFOXIDE, Menin, ...
Authors:Suzuki, M, Yoneyama, T, Imai, E.
Deposit date:2023-02-20
Release date:2023-03-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Cancer Cell Int, 23, 2023
8WGT
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BU of 8wgt by Molmil
Crystal structure of V30M-TTR in complex with compound 7
Descriptor: Transthyretin, [4,7-bis(chloranyl)-2-ethyl-1-benzofuran-3-yl]-[3,5-bis(iodanyl)-4-oxidanyl-phenyl]methanone
Authors:Yokoyama, T.
Deposit date:2023-09-22
Release date:2024-05-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J.Med.Chem., 67, 2024
8WGS
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BU of 8wgs by Molmil
Crystal structure of V30M-TTR in complex with compound 4
Descriptor: Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-(2-ethyl-4-iodanyl-1-benzofuran-3-yl)methanone
Authors:Yokoyama, T.
Deposit date:2023-09-22
Release date:2024-05-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J.Med.Chem., 67, 2024
8WGU
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BU of 8wgu by Molmil
Crystal structure of V30M-TTR in complex with compound 20
Descriptor: Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-[2-ethyl-4,7-bis(fluoranyl)-1-benzofuran-3-yl]methanone
Authors:Yokoyama, T.
Deposit date:2023-09-22
Release date:2024-05-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.508 Å)
Cite:Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J.Med.Chem., 67, 2024
1LMT
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BU of 1lmt by Molmil
STRUCTURE OF A CONFORMATIONALLY CONSTRAINED ARG-GLY-ASP SEQUENCE INSERTED INTO HUMAN LYSOZYME
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, HUMAN LYSOZYME
Authors:Matsushima, M, Song, H.
Deposit date:1995-01-13
Release date:1995-03-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a conformationally constrained Arg-Gly-Asp sequence inserted into human lysozyme.
J.Biol.Chem., 270, 1995
1J10
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BU of 1j10 by Molmil
beta-amylase from Bacillus cereus var. mycoides in complex with GGX
Descriptor: Beta-amylase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-xylopyranose, ...
Authors:Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J11
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BU of 1j11 by Molmil
beta-amylase from Bacillus cereus var. mycoides in complex with alpha-EPG
Descriptor: (2R)-oxiran-2-ylmethyl alpha-D-glucopyranoside, Beta-amylase, CALCIUM ION
Authors:Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J0Z
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BU of 1j0z by Molmil
Beta-amylase from Bacillus cereus var. mycoides in complex with maltose
Descriptor: Beta-amylase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J0Y
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BU of 1j0y by Molmil
Beta-amylase from Bacillus cereus var. mycoides in complex with glucose
Descriptor: Beta-amylase, CALCIUM ION, beta-D-glucopyranose
Authors:Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
5GSE
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BU of 5gse by Molmil
Crystal structure of unusual nucleosome
Descriptor: DNA (250-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kato, D, Osakabe, A, Arimura, Y, Park, S.Y, Kurumizaka, H.
Deposit date:2016-08-16
Release date:2017-05-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Crystal structure of the overlapping dinucleosome composed of hexasome and octasome
Science, 356, 2017
1J12
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BU of 1j12 by Molmil
Beta-Amylase from Bacillus cereus var. mycoides in Complex with alpha-EBG
Descriptor: 2-[(2S)-oxiran-2-yl]ethyl alpha-D-glucopyranoside, Beta-amylase, CALCIUM ION
Authors:Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
2RR7
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BU of 2rr7 by Molmil
Microtubule Binding Domain of DYNEIN-C
Descriptor: Dynein heavy chain 9
Authors:Kato, Y, Yagi, T, Ohki, S, Burgess, S, Honda, S, Kamiya, R, Tanokura, M.
Deposit date:2010-06-04
Release date:2011-06-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the microtubule-binding domain of flagellar dynein
Structure, 22, 2014
5GVI
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BU of 5gvi by Molmil
Zebrafish USP30 in complex with Lys6-linked diubiquitin
Descriptor: Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ubiquitin
Authors:Sato, Y, Fukai, S.
Deposit date:2016-09-05
Release date:2017-09-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30
Nat. Struct. Mol. Biol., 24, 2017

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