1ISR

Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion

Summary for 1ISR

Entry DOI	10.2210/pdb1isr/pdb
Related	1EWK 1EWT 1EWV 1ISS
Descriptor	Metabotropic Glutamate Receptor subtype 1, GLUTAMIC ACID, GADOLINIUM ATOM (3 entities in total)
Functional Keywords	signal transduction, neurotransmitter, g protein coupled receptor, agonist, gadolinium ion, signaling protein
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Cell membrane; Multi-pass membrane protein: P23385
Total number of polymer chains	1
Total formula weight	55720.34
Authors	Tsuchiya, D.,Kunishima, N.,Kamiya, N.,Jingami, H.,Morikawa, K. (deposition date: 2001-12-21, release date: 2002-03-13, Last modification date: 2023-10-25)
Primary citation	Tsuchiya, D.,Kunishima, N.,Kamiya, N.,Jingami, H.,Morikawa, K. Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+. Proc.Natl.Acad.Sci.USA, 99:2660-2665, 2002 Cited by PubMed: 11867751 DOI: 10.1073/pnas.052708599 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4 Å)

Structure validation