1ISR

Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GLU A 1001

Chain	Residue
A	TYR74
A	LYS409
A	SER164
A	SER165
A	SER186
A	ALA187
A	THR188
A	TYR236
A	ASP318
A	ARG323

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GD A 2001

Chain	Residue
A	GLU386
A	ASP493

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GD A 2002

Chain	Residue
A	GLU238
A	GLU238

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Functional Information from PROSITE/UniProt

site_id	PS00979
Number of Residues	19
Details	G_PROTEIN_RECEP_F3_1 G-protein coupled receptors family 3 signature 1. VqNLLqLFdIPQIAySATS

Chain	Residue	Details
A	VAL171-SER189

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11069170","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11867751","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"11069170","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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