1ISS
Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist
Summary for 1ISS
Entry DOI | 10.2210/pdb1iss/pdb |
Related | 1EWK 1EWT 1EWV 1ISR |
Descriptor | Metabotropic Glutamate Receptor subtype 1, (S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE (2 entities in total) |
Functional Keywords | signal transduction, neurotransmitter, g protein coupled receptor, antagonist, 4-carboxyphenylglycine, signaling protein |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cell membrane; Multi-pass membrane protein: P23385 |
Total number of polymer chains | 2 |
Total formula weight | 110935.81 |
Authors | Tsuchiya, D.,Kunishima, N.,Kamiya, N.,Jingami, H.,Morikawa, K. (deposition date: 2001-12-21, release date: 2002-03-13, Last modification date: 2023-10-25) |
Primary citation | Tsuchiya, D.,Kunishima, N.,Kamiya, N.,Jingami, H.,Morikawa, K. Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+. Proc.Natl.Acad.Sci.USA, 99:2660-2665, 2002 Cited by PubMed: 11867751DOI: 10.1073/pnas.052708599 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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