2L84
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![BU of 2l84 by Molmil](/molmil-images/mine/2l84) | Solution NMR structures of CBP bromodomain with small molecule j28 | Descriptor: | 5-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid, CREB-binding protein | Authors: | Borah, J.C, Mujtaba, S, Karakikes, I, Zeng, L, Muller, M, Patel, J, Moshkina, N, Morohashi, K, Zhang, W, Gerona-Navarro, G, Hajjar, R.J, Zhou, M. | Deposit date: | 2011-01-03 | Release date: | 2011-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes. Chem.Biol., 18, 2011
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7CHA
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![BU of 7cha by Molmil](/molmil-images/mine/7cha) | Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CH6
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![BU of 7ch6 by Molmil](/molmil-images/mine/7ch6) | Cryo-EM structure of E.coli MlaFEB with AMPPNP | Descriptor: | Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-08-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CH9
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![BU of 7ch9 by Molmil](/molmil-images/mine/7ch9) | Cryo-EM structure of P.aeruginosa MlaFEBD | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, Probable ATP-binding component of ABC transporter, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CH8
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![BU of 7ch8 by Molmil](/molmil-images/mine/7ch8) | Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ADP METAVANADATE, MAGNESIUM ION, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CH7
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![BU of 7ch7 by Molmil](/molmil-images/mine/7ch7) | Cryo-EM structure of E.coli MlaFEB | Descriptor: | Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, Phospholipid ABC transporter ATP-binding protein MlaF | Authors: | Zhou, C, Shi, H, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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2KVM
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2KWO
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![BU of 2kwo by Molmil](/molmil-images/mine/2kwo) | Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing N-terminal acetylation at Serine 1 | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-14 | Release date: | 2010-07-14 | Last modified: | 2013-06-19 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
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2KWN
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![BU of 2kwn by Molmil](/molmil-images/mine/2kwn) | Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing acetylation at Lysine 16 | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-13 | Release date: | 2010-07-14 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
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2KWK
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![BU of 2kwk by Molmil](/molmil-images/mine/2kwk) | Solution structures of the double PHD fingers of human transcriptional protein DPF3b bound to a H3 peptide wild type | Descriptor: | Histone peptide, ZINC ION, Zinc finger protein DPF3 | Authors: | Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M. | Deposit date: | 2010-04-12 | Release date: | 2010-07-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b. Nature, 466, 2010
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2L5D
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![BU of 2l5d by Molmil](/molmil-images/mine/2l5d) | Solution Structures of human PIWI-like 1 PAZ domain with ssRNA (5'-pUGACA) | Descriptor: | 5'-R(*UP*GP*AP*CP*A)-3', Piwi-like protein 1 | Authors: | Zeng, L, Zhang, Q, Yan, K, Zhou, M. | Deposit date: | 2010-10-29 | Release date: | 2011-04-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain. Proteins, 79, 2011
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2L5C
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5N3U
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![BU of 5n3u by Molmil](/molmil-images/mine/5n3u) | The structure of the complex of CpcE and CpcF of phycocyanin lyase from Nostoc sp. PCC7120 | Descriptor: | Phycocyanobilin lyase subunit alpha, Phycocyanobilin lyase subunit beta | Authors: | Hoeppner, A, Zhao, C, Xu, Q.-Z, Gaertner, W, Scheer, H, Zhao, K.-H. | Deposit date: | 2017-02-09 | Release date: | 2017-12-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structures and enzymatic mechanisms of phycobiliprotein lyases CpcE/F and PecE/F. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2KUB
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![BU of 2kub by Molmil](/molmil-images/mine/2kub) | Solution structure of the alpha subdomain of the major non-repeat unit of Fap1 fimbriae of Streptococcus parasanguis | Descriptor: | Fimbriae-associated protein Fap1 | Authors: | Ramboarina, S, Garnett, J.A, Bodey, A, Simpson, P, Bardiaux, B, Nilges, M, Matthews, S. | Deposit date: | 2010-02-17 | Release date: | 2010-07-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural insights into serine-rich fimbriae from gram-positive bacteria. J.Biol.Chem., 2010
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7MWH
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![BU of 7mwh by Molmil](/molmil-images/mine/7mwh) | Crystal structure of BAZ2A with DNA | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-17 | Release date: | 2022-08-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal structure of the BAZ2B TAM domain. Heliyon, 8, 2022
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2MJV
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6M1J
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![BU of 6m1j by Molmil](/molmil-images/mine/6m1j) | The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12x | Descriptor: | 1-[5-[6-fluoranyl-8-(methylamino)-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]cyclopropane-1-carboxylic acid, DIMETHYL SULFOXIDE, DNA gyrase subunit B, ... | Authors: | Xu, Z.H, Zhou, Z. | Deposit date: | 2020-02-26 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV. J.Med.Chem., 63, 2020
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6XKC
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![BU of 6xkc by Molmil](/molmil-images/mine/6xkc) | Crystal structure of E3 ligase | Descriptor: | Protein fem-1 homolog C | Authors: | Yan, X, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Dong, C, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-26 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron. Nat.Chem.Biol., 17, 2021
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6M1S
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![BU of 6m1s by Molmil](/molmil-images/mine/6m1s) | The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12o | Descriptor: | 3-[5-[8-(ethylamino)-6-fluoranyl-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]oxy-2,2-dimethyl-propanoic acid, CHLORIDE ION, DNA gyrase subunit B, ... | Authors: | Xu, Z.H, Zhou, Z. | Deposit date: | 2020-02-26 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.254 Å) | Cite: | Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV. J.Med.Chem., 63, 2020
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2L85
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![BU of 2l85 by Molmil](/molmil-images/mine/2l85) | Solution NMR structures of CBP bromodomain with small molecule of HBS | Descriptor: | 4-[(E)-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid, CREB-binding protein | Authors: | Borah, J.C, Mujtaba, S, Karakikes, I, Zeng, L, Muller, M, Patel, J, Moshkina, N, Morohashi, K, Zhang, W, Gerona-Navarro, G, Hajjar, R.J, Zhou, M. | Deposit date: | 2011-01-04 | Release date: | 2011-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes. Chem.Biol., 18, 2011
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5HEA
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![BU of 5hea by Molmil](/molmil-images/mine/5hea) | CgT structure in hexamer | Descriptor: | Putative glycosyltransferase (GalT1) | Authors: | Zhang, H, Wu, H. | Deposit date: | 2016-01-05 | Release date: | 2016-08-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | A new helical binding domain mediates a glycosyltransferase activity of a bifunctional protein To Be Published
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8K11
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![BU of 8k11 by Molmil](/molmil-images/mine/8k11) | SID1 transmembrane family member 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K12
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![BU of 8k12 by Molmil](/molmil-images/mine/8k12) | SID1 transmembrane family member 2 | Descriptor: | SID1 transmembrane family member 2 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K1B
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![BU of 8k1b by Molmil](/molmil-images/mine/8k1b) | SID1 transmembrane family member 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K10
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![BU of 8k10 by Molmil](/molmil-images/mine/8k10) | SID1 transmembrane family member 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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