6M1J

The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12x

Summary for 6M1J

• Entry DOI: 10.2210/pdb6m1j/pdb
• Descriptor: DNA gyrase subunit B, DIMETHYL SULFOXIDE, SULFATE ION, ... (6 entities in total)
• Functional Keywords: dna gyrase, topoisomerase, atpase domain, isomerase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 2
• Total formula weight: 49273.82

Authors

Xu, Z.H.,Zhou, Z. (deposition date: 2020-02-26, release date: 2020-09-02, Last modification date: 2023-11-29)

• Primary citation: Hu, Y.,Shi, H.,Zhou, M.,Ren, Q.,Zhu, W.,Zhang, W.,Zhang, Z.,Zhou, C.,Liu, Y.,Ding, X.,Shen, H.C.,Yan, S.F.,Dey, F.,Wu, W.,Zhai, G.,Zhou, Z.,Xu, Z.,Ji, Y.,Lv, H.,Jiang, T.,Wang, W.,Xu, Y.,Vercruysse, M.,Yao, X.,Mao, Y.,Yu, X.,Bradley, K.,Tan, X.; Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.; J.Med.Chem., 63:9623-9649, 2020; PubMed: 32787097; DOI: 10.1021/acs.jmedchem.0c00768

Experimental method

X-RAY DIFFRACTION (1.701 Å)