6M1J
The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12x
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA gyrase subunit B | polymer | 214 | 23939.8 | 2 | UniProt (Q9I7C2) Pfam (PF02518) | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | |
| 2 | C, H (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | G, I (A, B) | 1-[5-[6-fluoranyl-8-(methylamino)-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]cyclopropane-1-carboxylic acid | non-polymer | 511.4 | 2 | Chemie (EZ6) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence modifications
A, B: 17 - 221 (UniProt: Q9I7C2)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | expression tag |
| Leu 222 | - | expression tag |
| Glu 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
| His 226 | - | expression tag |
| His 227 | - | expression tag |
| His 228 | - | expression tag |
| His 229 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47879.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1394.2 | |
| All* | Total formula weight | 49273.8 |
