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6WX2
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BU of 6wx2 by Molmil
Vaccine-elicited mouse FP-targeting neutralizing antibody vFP16.02 with F60P mutation on light chain in complex with HIV fusion peptide (residue 512-519)
Descriptor: fusion peptide, vFP16.02 antibody heavy chain, vFP16.02 antibody light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2020-05-09
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 118, 2021
4MMS
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BU of 4mms by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION
Authors:Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMR
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BU of 4mmr by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
Authors:Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2021-06-02
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMV
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BU of 4mmv by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
Authors:Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2021-06-02
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMU
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BU of 4mmu by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ...
Authors:Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
6WXL
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BU of 6wxl by Molmil
Cryo-EM structure of the VRC315 clinical trial, vaccine-elicited, human antibody 1D12 in complex with an H7 SH13 HA trimer
Descriptor: 1D12 Light chain, 1D21 Heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-05-11
Release date:2021-06-09
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.
Structure, 2022
4MMT
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BU of 4mmt by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
Authors:Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
6WIX
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BU of 6wix by Molmil
Crystal Structure of HIV-1 MI369 RnS-DS.SOSIP Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Olia, A, Kwong, P.D.
Deposit date:2020-04-10
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.
Cell Rep, 33, 2020
7SG4
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BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
4MMQ
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BU of 4mmq by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS
Descriptor: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION
Authors:Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
6UBI
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BU of 6ubi by Molmil
N123-VRC34.05 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide 512-519, VRC34.05 heavy chain, VRC34.05 light chain
Authors:Xu, K, Liu, K, Kwong, P.D.
Deposit date:2019-09-11
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6UDA
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BU of 6uda by Molmil
Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH235 UCA heavy chain Fab, CH235 UCA light chain Fab, ...
Authors:Henderson, R, Acharya, P.
Deposit date:2019-09-19
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies.
Plos Pathog., 15, 2019
6UCE
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BU of 6uce by Molmil
N123-VRC34_pI3 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI3 heavy chain, N123-VRC34_pI3 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.382 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6UCF
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BU of 6ucf by Molmil
N123-VRC34_pI4 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI4 heavy chain, N123-VRC34_pI4 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6MJZ
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BU of 6mjz by Molmil
Cryo-EM structure of Human Parainfluenza Virus Type 3 (hPIV3) in complex with antibody PIA174
Descriptor: Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain
Authors:Acharya, P, Stewart-Jones, G, Carragher, B, Potter, C.S, Kwong, P.D.
Deposit date:2018-09-24
Release date:2018-11-14
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MQM
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BU of 6mqm by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor: HIV Env fusion peptide residue 512-519, antibody Fab heavy chain, antibody Fab light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3.484 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQR
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BU of 6mqr by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519)
Descriptor: CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ...
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQC
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BU of 6mqc by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
Descriptor: 0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MPH
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BU of 6mph by Molmil
Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ...
Authors:Acharya, P, Xu, K, Kwong, P.D.
Deposit date:2018-10-06
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N16
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BU of 6n16 by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-b.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor: HIV fusion peptide (512-519), antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-11-08
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N1W
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BU of 6n1w by Molmil
Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DFPH-a.15 Light chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-11-12
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N1V
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BU of 6n1v by Molmil
Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody A12V163-a.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-a.01 Heavy chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-11-12
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQE
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BU of 6mqe by Molmil
Vaccine-elicited NHP FP-targeting HIV neutralizing antibody DFPH-a.15 in complex with HIV fusion peptide (residue 512-519)
Descriptor: DFPHa.15 antibody Fab heavy chain, DFPHa.15 antibody Fab light chain, HIV fusion peptide
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.459 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MPG
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BU of 6mpg by Molmil
Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-10-06
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQS
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BU of 6mqs by Molmil
Vaccine-elicited NHP FP-targeting HIV neutralizing antibody A12V163-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor: HIV fusion peptide residue 512-519, antibody A12V163-a.01 heavy chain, antibody A12V163-a.01 light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019

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PDB entries from 2024-09-11

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