7PDX
| Crystal structure of parent MAGE-A10 TCR (728) | Descriptor: | CHLORIDE ION, PHOSPHATE ION, T-cell receptor alpha chain (TRAV/TRAC), ... | Authors: | Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. | Deposit date: | 2021-08-09 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10, 2022
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7QPJ
| Crystal structure of engineered TCR (756) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide | Descriptor: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | Authors: | Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. | Deposit date: | 2022-01-04 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy. J Immunother Cancer, 10, 2022
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4ACH
| GSK3b in complex with inhibitor | Descriptor: | 3-AMINO-N-(3-METHOXYPROPYL)-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}PYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Xue, Y, Ormo, M. | Deposit date: | 2011-12-15 | Release date: | 2012-05-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
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4ACD
| GSK3b in complex with inhibitor | Descriptor: | 3-AMINO-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Xue, Y, Ormo, M. | Deposit date: | 2011-12-15 | Release date: | 2012-05-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
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4ACG
| GSK3b in complex with inhibitor | Descriptor: | 2-AMINO-5-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-[4-(PYRROLIDIN-1-YLMETHYL)PYRIDIN-3-YL]PYRIDINE-3-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Xue, Y, Ormo, M. | Deposit date: | 2011-12-15 | Release date: | 2012-05-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
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4ACC
| GSK3b in complex with inhibitor | Descriptor: | 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, DIMETHYL SULFOXIDE, GLYCOGEN SYNTHASE KINASE-3 BETA | Authors: | Xue, Y, Ormo, M. | Deposit date: | 2011-12-14 | Release date: | 2012-05-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
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2VFO
| Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V125L | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFM
| Low Temperature Structure of P22 Tailspike Protein Fragment (109-666) | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, GLYCEROL, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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7BET
| Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane | Descriptor: | FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta | Authors: | Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B. | Deposit date: | 2020-12-24 | Release date: | 2022-01-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL To Be Published
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2VFQ
| Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V450A | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN,, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFN
| Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V125A | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, GLYCEROL, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFP
| Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V349L | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2J98
| Human coronavirus 229E non structural protein 9 cys69ala mutant (Nsp9) | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, REPLICASE POLYPROTEIN 1AB | Authors: | Ponnusamy, R, Mesters, J.R, Moll, R, Hilgenfeld, R. | Deposit date: | 2006-11-03 | Release date: | 2007-11-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Variable Oligomerization Modes in Coronavirus Non-Structural Protein 9. J.Mol.Biol., 383, 2008
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2J97
| Human coronavirus 229E non structural protein 9 (Nsp9) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, REPLICASE POLYPROTEIN 1AB, SULFATE ION | Authors: | Ponnusamy, R, Mesters, J.R, Moll, R, Hilgenfeld, R. | Deposit date: | 2006-11-03 | Release date: | 2007-11-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Variable Oligomerization Modes in Coronavirus Non-Structural Protein 9. J.Mol.Biol., 383, 2008
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2N0X
| Three dimensional structure of EPI-X4, a human albumin-derived peptide that regulates innate immunity through the CXCR4/CXCL12 chemotactic axis and antagonizes HIV-1 entry | Descriptor: | Serum albumin | Authors: | Perez-Castells, J, Canales, A, Jimenez-Barbero, J, Gimenez-Gallego, G. | Deposit date: | 2015-03-18 | Release date: | 2015-04-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Discovery and characterization of an endogenous CXCR4 antagonist. Cell Rep, 11, 2015
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5O5L
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5O5K
| X-ray structure of a bacterial adenylyl cyclase soluble domain | Descriptor: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ... | Authors: | Vercellino, I, Korkhov, V.M. | Deposit date: | 2017-06-02 | Release date: | 2017-11-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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