7PDX

Crystal structure of parent MAGE-A10 TCR (728)

This is a non-PDB format compatible entry.

Summary for 7PDX

• Entry DOI: 10.2210/pdb7pdx/pdb
• Related: 7PBC 7PDW
• Descriptor: T-cell receptor alpha chain (TRAV/TRAC), T-cell receptor beta chain (TRBV/TRBC), CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: t-cell receptor, immunoglobulin fold, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 100172.87

Authors

Simister, P.C.,Border, E.C.,Vieira, J.F.,Pumphrey, N.J. (deposition date: 2021-08-09, release date: 2022-08-03, Last modification date: 2024-01-31)

• Primary citation: Simister, P.C.,Border, E.C.,Vieira, J.F.,Pumphrey, N.J.; Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.; J Immunother Cancer, 10:-, 2022; PubMed: 35851311; DOI: 10.1136/jitc-2022-004600

Experimental method

X-RAY DIFFRACTION (2.27 Å)