4JKZ
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![BU of 4jkz by Molmil](/molmil-images/mine/4jkz) | Crystal structure of ms6564 from mycobacterium smegmatis | Descriptor: | Transcriptional regulator, TetR family | Authors: | Yang, S.F, Gao, Z.Q, He, Z.G, Dong, Y.H. | Deposit date: | 2013-03-12 | Release date: | 2013-06-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for interaction between Mycobacterium smegmatis Ms6564, a TetR family master regulator, and its target DNA. J.Biol.Chem., 288, 2013
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7CSW
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![BU of 7csw by Molmil](/molmil-images/mine/7csw) | Pseudomonas aeruginosa antitoxin HigA with pa2440 promoter | Descriptor: | HTH cro/C1-type domain-containing protein, pa2440 | Authors: | Song, Y.J, Luo, G.H, Bao, R. | Deposit date: | 2020-08-17 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
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7CSV
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![BU of 7csv by Molmil](/molmil-images/mine/7csv) | Pseudomonas aeruginosa antitoxin HigA | Descriptor: | HTH cro/C1-type domain-containing protein | Authors: | Song, Y.J, Luo, G.H, Bao, R. | Deposit date: | 2020-08-17 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
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4HCN
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![BU of 4hcn by Molmil](/molmil-images/mine/4hcn) | Crystal structure of Burkholderia pseudomallei effector protein CHBP in complex with ubiquitin | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, PHOSPHATE ION, ... | Authors: | Yao, Q, Cui, J, Zhu, Y, Shao, F. | Deposit date: | 2012-09-30 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis. Proc.Natl.Acad.Sci.USA, 109, 2012
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4HCP
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![BU of 4hcp by Molmil](/molmil-images/mine/4hcp) | |
7CSY
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![BU of 7csy by Molmil](/molmil-images/mine/7csy) | Pseudomonas aeruginosa antitoxin HigA with higBA promoter | Descriptor: | DNA (28-MER), DNA (29-MER), HTH cro/C1-type domain-containing protein, ... | Authors: | Song, Y.J, Luo, G.H, Bao, R. | Deposit date: | 2020-08-17 | Release date: | 2021-01-13 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
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7X7V
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![BU of 7x7v by Molmil](/molmil-images/mine/7x7v) | Cryo-EM structure of SARS-CoV spike protein in complex with three nAbs X01, X10 and X17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | Authors: | Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2022-03-10 | Release date: | 2022-08-17 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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4JL3
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![BU of 4jl3 by Molmil](/molmil-images/mine/4jl3) | Crystal structure of ms6564-dna complex | Descriptor: | DNA (31-MER), Transcriptional regulator, TetR family | Authors: | Yang, S.F, Gao, Z.Q, He, Z.G, Dong, Y.H. | Deposit date: | 2013-03-12 | Release date: | 2013-06-26 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for interaction between Mycobacterium smegmatis Ms6564, a TetR family master regulator, and its target DNA. J.Biol.Chem., 288, 2013
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7CVA
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![BU of 7cva by Molmil](/molmil-images/mine/7cva) | RNA methyltransferase METTL4 | Descriptor: | Methyltransferase-like protein 2 | Authors: | Luo, Q, Ma, J. | Deposit date: | 2020-08-25 | Release date: | 2021-09-01 | Last modified: | 2022-10-12 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 Nat Commun, 13, 2022
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7CV9
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![BU of 7cv9 by Molmil](/molmil-images/mine/7cv9) | RNA methyltransferase METTL4 | Descriptor: | GLYCEROL, Methyltransferase-like protein 2, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Luo, Q, Ma, J. | Deposit date: | 2020-08-25 | Release date: | 2021-09-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.455 Å) | Cite: | Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 Nat Commun, 13, 2022
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7CV6
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![BU of 7cv6 by Molmil](/molmil-images/mine/7cv6) | RNA methyltransferase METTL4 | Descriptor: | 2'-O-methyladenosine 5'-(dihydrogen phosphate), Methyltransferase-like protein 2, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Luo, Q, Ma, J. | Deposit date: | 2020-08-25 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 Nat Commun, 13, 2022
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7CV7
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![BU of 7cv7 by Molmil](/molmil-images/mine/7cv7) | RNA methyltransferase METTL4 | Descriptor: | Methyltransferase-like protein 2, S-ADENOSYLMETHIONINE | Authors: | Luo, Q, Ma, J. | Deposit date: | 2020-08-25 | Release date: | 2021-09-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 Nat Commun, 13, 2022
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7CV8
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![BU of 7cv8 by Molmil](/molmil-images/mine/7cv8) | RNA methyltransferase METTL4 | Descriptor: | GLYCEROL, Methyltransferase-like protein 2, SINEFUNGIN | Authors: | Luo, Q, Ma, J. | Deposit date: | 2020-08-25 | Release date: | 2021-09-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 Nat Commun, 13, 2022
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7X7T
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![BU of 7x7t by Molmil](/molmil-images/mine/7x7t) | Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | Authors: | Sun, H, Liu, L, Zheng, Q, Li, S, Zhang, T, Xia, N. | Deposit date: | 2022-03-10 | Release date: | 2022-08-17 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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7X7U
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![BU of 7x7u by Molmil](/molmil-images/mine/7x7u) | Cryo-EM structure of SARS-CoV-2 Delta variant spike protein in complex with three nAbs X01, X10 and X17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ... | Authors: | Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2022-03-10 | Release date: | 2022-08-17 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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8JJ9
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![BU of 8jj9 by Molmil](/molmil-images/mine/8jj9) | |
8KHR
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![BU of 8khr by Molmil](/molmil-images/mine/8khr) | Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1 | Descriptor: | 2C1 heavy chain, 2C1 light chain, Envelope glycoprotein H, ... | Authors: | Fang, X.Y, Zhao, G.X, Zeng, M.S, Liu, Z. | Deposit date: | 2023-08-22 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection. Cell Rep Med, 5, 2024
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8F0Q
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![BU of 8f0q by Molmil](/molmil-images/mine/8f0q) | Structure of VSD4-NaV1.7-NaVPas channel chimera bound to the acylsulfonamide inhibitor GDC-0310 | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-cyclopropyl-4-({1-[(1S)-1-(3,5-dichlorophenyl)ethyl]piperidin-4-yl}methoxy)-2-fluoro-N-(methanesulfonyl)benzamide, ... | Authors: | Kschonsak, M, Jao, C.C, Arthur, C.P, Rohou, A.L, Bergeron, P, Ortwine, D, McKerall, S.J, Hackos, D.H, Deng, L, Chen, J, Sutherlin, D, Dragovich, P.S, Volgraf, M, Wright, M.R, Payandeh, J, Ciferri, C, Tellis, J.C. | Deposit date: | 2022-11-03 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM reveals an unprecedented binding site for Na V 1.7 inhibitors enabling rational design of potent hybrid inhibitors. Elife, 12, 2023
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8F0S
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![BU of 8f0s by Molmil](/molmil-images/mine/8f0s) | Structure of VSD4-NaV1.7-NaVPas channel chimera bound to the hybrid inhibitor GNE-9296 | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kschonsak, M, Jao, C.C, Arthur, C.P, Rohou, A.L, Bergeron, P, Ortwine, D, McKerall, S.J, Hackos, D.H, Deng, L, Chen, J, Sutherlin, D, Dragovich, P.S, Volgraf, M, Wright, M.R, Payandeh, J, Ciferri, C, Tellis, J.C. | Deposit date: | 2022-11-03 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM reveals an unprecedented binding site for Na V 1.7 inhibitors enabling rational design of potent hybrid inhibitors. Elife, 12, 2023
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8F0P
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![BU of 8f0p by Molmil](/molmil-images/mine/8f0p) | Structure of VSD4-NaV1.7-NaVPas channel chimera bound to the hybrid inhibitor GNE-1305 | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Kschonsak, M, Jao, C.C, Arthur, C.P, Rohou, A.L, Bergeron, P, Ortwine, D, McKerall, S.J, Hackos, D.H, Deng, L, Chen, J, Sutherlin, D, Dragovich, P.S, Volgraf, M, Wright, M.R, Payandeh, J, Ciferri, C, Tellis, J.C. | Deposit date: | 2022-11-03 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM reveals an unprecedented binding site for Na V 1.7 inhibitors enabling rational design of potent hybrid inhibitors. Elife, 12, 2023
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8F0R
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![BU of 8f0r by Molmil](/molmil-images/mine/8f0r) | Structure of VSD4-NaV1.7-NaVPas channel chimera bound to the arylsulfonamide inhibitor GNE-3565 | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-4-({(1S,2S,4S)-2-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]cyclohexyl}amino)-2-fluoro-N-(pyrimidin-4-yl)benzene-1-sulfonamide, ... | Authors: | Kschonsak, M, Jao, C.C, Arthur, C.P, Rohou, A.L, Bergeron, P, Ortwine, D, McKerall, S.J, Hackos, D.H, Deng, L, Chen, J, Sutherlin, D, Dragovich, P.S, Volgraf, M, Wright, M.R, Payandeh, J, Ciferri, C, Tellis, J.C. | Deposit date: | 2022-11-03 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM reveals an unprecedented binding site for Na V 1.7 inhibitors enabling rational design of potent hybrid inhibitors. Elife, 12, 2023
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6JIF
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![BU of 6jif by Molmil](/molmil-images/mine/6jif) | Crystal Structures of Branched-Chain Aminotransferase from Pseudomonas sp. UW4 | Descriptor: | Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Zheng, X, Guo, L, Li, D.F, Wu, B. | Deposit date: | 2019-02-21 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and structural characterization of a highly active branched-chain amino acid aminotransferase from Pseudomonas sp. for efficient biosynthesis of chiral amino acids. Appl.Microbiol.Biotechnol., 103, 2019
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7X38
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![BU of 7x38 by Molmil](/molmil-images/mine/7x38) | Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 8A10 (CVB1-E:8A10) | Descriptor: | 8A10 heavy chain, 8A10 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X3F
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![BU of 7x3f by Molmil](/molmil-images/mine/7x3f) | Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 9A3 (CVB1-A:9A3) | Descriptor: | 9A3 heavy chain, 9A3 light chain, VP2, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-02-28 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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7X42
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![BU of 7x42 by Molmil](/molmil-images/mine/7x42) | Cryo-EM structure of Coxsackievirus B1 pre-A-particle in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 2E6) | Descriptor: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP0, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-01 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
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