1IE3
| CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE | Descriptor: | MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID | Authors: | Bell, J.K, Yennawar, H.P, Wright, S.K, Thompson, J.R, Viola, R.E, Banaszak, L.J. | Deposit date: | 2001-04-05 | Release date: | 2001-09-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Analyses of a Malate Dehydrogenase with a Variable Active Site J.Biol.Chem., 276, 2001
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4UBE
| CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE | Descriptor: | 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Adenosine kinase | Authors: | Reddy, M.C.M, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Watson, M.D, Sacchettini, J.C. | Deposit date: | 2014-08-12 | Release date: | 2014-09-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.933 Å) | Cite: | CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE TO BE PUBLISHED
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6PX5
| CRYSTAL STRUCTURE OF HUMAN MEIZOTHROMBIN DESF1 MUTANT S195A bound with PPACK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Prothrombin, ... | Authors: | Pelc, L.A, Koester, S.K, Chen, Z, Gistover, N, Di Cera, E. | Deposit date: | 2019-07-24 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Residues W215, E217 and E192 control the allosteric E*-E equilibrium of thrombin. Sci Rep, 9, 2019
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6PXQ
| Crystal structure of human thrombin mutant D194A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin heavy chain, Thrombin light chain | Authors: | Stojanovski, B, Chen, Z, Koester, S.K, Pelc, L.A, Di Cera, E. | Deposit date: | 2019-07-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9, 2019
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2C0X
| MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA | Descriptor: | COAT PROTEIN B | Authors: | Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K. | Deposit date: | 2005-09-08 | Release date: | 2005-12-14 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane. J.Mol.Biol., 355, 2006
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4AS7
| Eg5 complex 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, CHLORIDE ION, ... | Authors: | Talapatra, S.K, Kozielski, F. | Deposit date: | 2012-04-29 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism. J.Med.Chem., 56, 2013
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2BME
| high resolution structure of GppNHp-bound human Rab4a | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | Authors: | Scheidig, A.J, Huber, S.K. | Deposit date: | 2005-03-13 | Release date: | 2005-04-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | High Resolution Crystal Structures of Human Rab4A in its Active and Inactive Conformations. FEBS Lett., 579, 2005
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4BEX
| Structure of human Cofilin1 | Descriptor: | COFILIN-1 | Authors: | Klejnot, M, Gabrielsen, M, Cameron, J, Mleczak, A, Talapatra, S.K, Kozielski, F, Pannifer, A, Olson, M.F. | Deposit date: | 2013-03-12 | Release date: | 2013-08-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of the Human Cofilin1 Structure Reveals Conformational Changes Required for Actin-Binding Acta Crystallogr.,Sect.D, 69, 2013
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2C0W
| Molecular Structure of fd Filamentous Bacteriophage Refined with Respect to X-ray Fibre Diffraction | Descriptor: | COAT PROTEIN B | Authors: | Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K. | Deposit date: | 2005-09-08 | Release date: | 2005-12-14 | Last modified: | 2024-02-14 | Method: | FIBER DIFFRACTION (3.2 Å) | Cite: | Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane. J.Mol.Biol., 355, 2006
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7AJR
| Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors | Descriptor: | 2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic acid, Keratinase KP2, SULFATE ION, ... | Authors: | Leiris, S, Davies, D.T, Sprinsky, N, Castandet, J, Behria, L, Bodnarchuk, M.S, Sutton, J.M, Mullins, T.M.G, Jones, M.W, Forrest, A.K, Pallin, T.D, Karunakar, P, Martha, S.K, Parusharamulu, B, Ramula, R, Kotha, V, Pottabathini, N, Pothukanuri, S, Lemonnier, M, Everett, M. | Deposit date: | 2020-09-29 | Release date: | 2021-02-10 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors. Acs Med.Chem.Lett., 12, 2021
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1JFI
| Crystal Structure of the NC2-TBP-DNA Ternary Complex | Descriptor: | 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ... | Authors: | Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2001-06-20 | Release date: | 2001-07-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell(Cambridge,Mass.), 106, 2001
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6YSW
| E. coli anaerobic trifunctional enzyme subunit-alpha in complex with coenzyme A | Descriptor: | COENZYME A, Fatty acid oxidation complex subunit alpha, SULFATE ION | Authors: | Sah-Teli, S.K, Hynonen, M.J, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2020-04-23 | Release date: | 2021-05-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes Structure, 2023
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6YSV
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4UG0
| STRUCTURE OF THE HUMAN 80S RIBOSOME | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... | Authors: | Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. | Deposit date: | 2015-03-20 | Release date: | 2015-06-10 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the human 80S ribosome NATURE, 520, 2015
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8SF7
| 48-nm doublet microtubule from Tetrahymena thermophila strain MEC17 | Descriptor: | CFAM166A, CFAM166B, CFAM166C, ... | Authors: | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | Deposit date: | 2023-04-10 | Release date: | 2024-05-22 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Effect of alpha-tubulin acetylation on the doublet microtubule structure. Elife, 12, 2024
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4UNI
| beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 in complex with galactose | Descriptor: | BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Viborg, A.H, Fredslund, F, Katayama, T, Nielsen, S.K, Svensson, B, Kitaoka, M, Lo Leggio, L, Abou Hachem, M. | Deposit date: | 2014-05-28 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A beta 1-6/ beta 1-3 galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of beta-galactoside catabolism within Bifidobacterium. Mol. Microbiol., 2014
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4UBF
| HsMCAK motor domain complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION | Authors: | Welburn, J.P.I, Talapatra, S.K. | Deposit date: | 2014-08-12 | Release date: | 2015-05-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch. Elife, 4, 2015
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4UOQ
| Nucleophile mutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 | Descriptor: | BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | Authors: | Viborg, A.H, Fredslund, F, Katayama, T, Nielsen, S.K, Svensson, B, Kitaoka, M, Lo Leggio, L, Abou Hachem, M. | Deposit date: | 2014-06-09 | Release date: | 2014-10-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A beta 1-6/ beta 1-3 galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of beta-galactoside catabolism within Bifidobacterium. Mol. Microbiol., 2014
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4UOZ
| beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose | Descriptor: | BETA-GALACTOSIDASE, TRIETHYLENE GLYCOL, ZINC ION, ... | Authors: | Viborg, A.H, Fredslund, F, Katayama, T, Nielsen, S.K, Svensson, B, Kitaoka, M, Lo Leggio, L, Abou Hachem, M. | Deposit date: | 2014-06-11 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A beta 1-6/ beta 1-3 galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of beta-galactoside catabolism within Bifidobacterium. Mol. Microbiol., 2014
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6UKJ
| Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform | Descriptor: | CHOLESTEROL HEMISUCCINATE, Chloroquine resistance transporter, Fab Heavy Chain, ... | Authors: | Kim, J, Tan, Y.Z, Wicht, K.J, Erramilli, S.K, Dhingra, S.K, Okombo, J, Vendome, J, Hagenah, L.M, Giacometti, S.I, Warren, A.L, Nosol, K, Roepe, P.D, Potter, C.S, Carragher, B, Kossiakoff, A.A, Quick, M, Fidock, D.A, Mancia, F. | Deposit date: | 2019-10-05 | Release date: | 2019-12-04 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Nature, 576, 2019
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6SO9
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6SOE
| Mouse RBM20 RRM domain | Descriptor: | RNA-binding protein 20 | Authors: | Mackereth, C.D, Upadhyay, S.K. | Deposit date: | 2019-08-29 | Release date: | 2019-11-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural basis of UCUU RNA motif recognition by splicing factor RBM20. Nucleic Acids Res., 48, 2020
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4WD9
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8H17
| Crystal structure of the Globin domain of Thermosynechococcus elongatus BP-1 | Descriptor: | IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, Tlr1989 protein | Authors: | Mathur, S, Yadav, S.K, Pal, K.R, Kundu, S. | Deposit date: | 2022-09-30 | Release date: | 2023-04-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A novel single sensor hemoglobin domain from the thermophilic cyanobacteria Thermosynechococcus elongatus BP-1 exhibits higher pH but lower thermal stability compared to globins from mesophilic organisms. Int.J.Biol.Macromol., 240, 2023
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4W1U
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