8JHH
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![BU of 8jhh by Molmil](/molmil-images/mine/8jhh) | Glycoside hydrolase family 55 endo-beta-1,3-glucanase from Microdochium nivale | Descriptor: | GLYCEROL, MnLam55A | Authors: | Ota, T, Saburi, W, Yamashita, K, Tagami, T, Yu, J, Komba, S, Jewell, L.E, Hsiang, T, Imai, R, Yao, M, Mori, H. | Deposit date: | 2023-05-23 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular mechanism for endo-type action of glycoside hydrolase family 55 endo-beta-1,3-glucanase on beta 1-3/1-6-glucan. J.Biol.Chem., 299, 2023
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6M5W
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![BU of 6m5w by Molmil](/molmil-images/mine/6m5w) | Co-crystal structure of human serine hydroxymethyltransferase 1 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Ota, T, Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K, Sando, S. | Deposit date: | 2020-03-11 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate. Iscience, 24, 2021
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6M5O
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![BU of 6m5o by Molmil](/molmil-images/mine/6m5o) | Co-crystal structure of human serine hydroxymethyltransferase 2 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCINE, Serine hydroxymethyltransferase, ... | Authors: | Ota, T, Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K, Sando, S. | Deposit date: | 2020-03-11 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.30000663 Å) | Cite: | Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate. Iscience, 24, 2021
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5XFV
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![BU of 5xfv by Molmil](/molmil-images/mine/5xfv) | Crystal structures of FMN-bound form of dihydroorotate dehydrogenase from Trypanosoma brucei | Descriptor: | Dihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, MALONATE ION | Authors: | Kubota, T, Tani, O, Yamaguchi, T, Namatame, I, Sakashita, H, Furukawa, K, Yamasaki, K. | Deposit date: | 2017-04-11 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase fromTrypanosoma brucei. FEBS Open Bio, 8, 2018
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5XFW
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![BU of 5xfw by Molmil](/molmil-images/mine/5xfw) | Crystal structures of FMN-free form of dihydroorotate dehydrogenase from Trypanosoma brucei | Descriptor: | Dihydroorotate dehydrogenase (fumarate), MALONATE ION | Authors: | Kubota, T, Tani, O, Yamaguchi, T, Namatame, I, Sakashita, H, Furukawa, K, Yamasaki, K. | Deposit date: | 2017-04-11 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase fromTrypanosoma brucei. FEBS Open Bio, 8, 2018
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1JIB
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![BU of 1jib by Molmil](/molmil-images/mine/1jib) | Complex of Alpha-amylase II (TVA II) from Thermoactinomyces vulgaris R-47 with Maltotetraose Based on a Crystal Soaked with Maltohexaose. | Descriptor: | NEOPULLULANASE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Yokota, T, Tonozuka, T, Shimura, Y, Ichikawa, K, Kamitori, S, Sakano, Y. | Deposit date: | 2001-07-02 | Release date: | 2001-07-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of Thermoactinomyces vulgaris R-47 alpha-amylase II complexed with substrate analogues. Biosci.Biotechnol.Biochem., 65, 2001
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3ASQ
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![BU of 3asq by Molmil](/molmil-images/mine/3asq) | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with H-antigen | Descriptor: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | Authors: | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | Deposit date: | 2010-12-17 | Release date: | 2012-01-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3ASR
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![BU of 3asr by Molmil](/molmil-images/mine/3asr) | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with Lewis-a | Descriptor: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | Authors: | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | Deposit date: | 2010-12-17 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3ASS
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![BU of 3ass by Molmil](/molmil-images/mine/3ass) | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with Lewis-b | Descriptor: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | Authors: | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | Deposit date: | 2010-12-17 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3ASP
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![BU of 3asp by Molmil](/molmil-images/mine/3asp) | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with A-antigen | Descriptor: | Capsid protein, SODIUM ION, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | Deposit date: | 2010-12-17 | Release date: | 2012-01-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3AST
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![BU of 3ast by Molmil](/molmil-images/mine/3ast) | Crystal structure of P domain Q389N mutant from Norovirus Funabashi258 stain in the complex with Lewis-b | Descriptor: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | Authors: | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | Deposit date: | 2010-12-17 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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2D7I
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![BU of 2d7i by Molmil](/molmil-images/mine/2d7i) | Crystal structure of pp-GalNAc-T10 with UDP, GalNAc and Mn2+ | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kubota, T, Shiba, T, Sugioka, S, Kato, R, Wakatsuki, S, Narimatsu, H. | Deposit date: | 2005-11-21 | Release date: | 2006-11-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10) J.Mol.Biol., 359, 2006
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2D7R
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![BU of 2d7r by Molmil](/molmil-images/mine/2d7r) | Crystal structure of pp-GalNAc-T10 complexed with GalNAc-Ser on lectin domain | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kubota, T, Shiba, T, Sugioka, S, Kato, R, Wakatsuki, S, Narimatsu, H. | Deposit date: | 2005-11-25 | Release date: | 2006-11-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10) J.Mol.Biol., 359, 2006
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1JL8
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![BU of 1jl8 by Molmil](/molmil-images/mine/1jl8) | Complex of alpha-amylase II (TVA II) from Thermoactinomyces vulgaris R-47 with beta-cyclodextrin based on a co-crystallization with methyl beta-cyclodextrin | Descriptor: | ALPHA-AMYLASE II, Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | Authors: | Yokota, T, Tonozuka, T, Shimura, Y, Ichikawa, K, Kamitori, S, Sakano, Y. | Deposit date: | 2001-07-16 | Release date: | 2001-08-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of Thermoactinomyces vulgaris R-47 alpha-amylase II complexed with substrate analogues. Biosci.Biotechnol.Biochem., 65, 2001
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1X3X
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![BU of 1x3x by Molmil](/molmil-images/mine/1x3x) | Crystal Structure of Cytochrome b5 from Ascaris suum | Descriptor: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Yokota, T, Nakajima, Y, Yamakura, F, Sugio, S, Hashimoto, M, Takamiya, S, Aoki, T. | Deposit date: | 2005-05-11 | Release date: | 2006-06-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Unique structure of Ascaris suum b5-type cytochrome: an additional alpha-helix and positively charged residues on the surface domain interact with redox partners Biochem.J., 394, 2006
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1WRM
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![BU of 1wrm by Molmil](/molmil-images/mine/1wrm) | Crystal structure of JSP-1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, dual specificity phosphatase 22 | Authors: | Yokota, T, Kashima, A, Kato, R, Sugio, S. | Deposit date: | 2004-10-22 | Release date: | 2005-10-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution Proteins, 66, 2006
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7F4B
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![BU of 7f4b by Molmil](/molmil-images/mine/7f4b) | The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | Descriptor: | MAGNESIUM ION, homoserine dehydrogenase | Authors: | Kurihara, E, Kubota, T, Watanabe, K, Ogata, K, Kaneko, R, Oshima, T, Yoshimune, K, Goto, M. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase. Commun Biol, 5, 2022
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7F4C
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![BU of 7f4c by Molmil](/molmil-images/mine/7f4c) | The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | Descriptor: | 1,4-BUTANEDIOL, Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Ogata, K, Kaneko, R, Kubota, T, Watanabe, K, Kurihara, E, Oshima, T, Yoshimune, K, Goto, M. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase. Commun Biol, 5, 2022
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8H25
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![BU of 8h25 by Molmil](/molmil-images/mine/8h25) | Lacticaseibacillus casei GH35 beta-galactosidase LBCZ_0230 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-galactosidase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Saburi, W, Ota, T, Kato, K, Tagami, T, Yamashita, K, Yao, M, Mori, H. | Deposit date: | 2022-10-04 | Release date: | 2023-08-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Function and Structure of Lacticaseibacillus casei GH35 beta-Galactosidase LBCZ_0230 with High Hydrolytic Activity to Lacto- N -biose I and Galacto- N -biose. J Appl Glycosci (1999), 70, 2023
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3VQU
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![BU of 3vqu by Molmil](/molmil-images/mine/3vqu) | CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 4-[(4-amino-5-cyano-6-ethoxypyridin-2- yl)amino]benzamide | Descriptor: | 4-[(4-amino-5-cyano-6-ethoxypyridin-2-yl)amino]benzamide, Dual specificity protein kinase TTK, IODIDE ION | Authors: | Kusakabe, K, Ide, N, Daigo, Y, Itoh, T, Higashino, K, Okano, Y, Tadano, G, Tachibana, Y, Sato, Y, Inoue, M, Wada, T, Iguchi, M, Kanazawa, T, Ishioka, Y, Dohi, K, Tagashira, S, Kido, Y, Sakamoto, S, Yasuo, K, Maeda, M, Yamamoto, T, Higaki, M, Endoh, T, Ueda, K, Shiota, T, Murai, H, Nakamura, Y. | Deposit date: | 2012-03-30 | Release date: | 2012-06-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation. Acs Med.Chem.Lett., 3, 2012
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3MJ4
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![BU of 3mj4 by Molmil](/molmil-images/mine/3mj4) | Crystal structure of UDP-galactopyranose mutase in complex with phosphonate analog of UDP-galactopyranose | Descriptor: | (((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)methyl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Karunan Partha, S, Sadeghi-Khomami, A, Slowski, K, Kotake, T, Thomas, N.R, Jakeman, D.L, Sanders, D.A.R. | Deposit date: | 2010-04-12 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase. J.Mol.Biol., 403, 2010
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6LFF
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![BU of 6lff by Molmil](/molmil-images/mine/6lff) | transcription factor SATB1 CUTr1 domain in complex with a phosphorothioate DNA | Descriptor: | DNA (5'-D(*GP*(C7R)P*(PST)P*AP*AP*TP*AP*TP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*(AS)P*(PST)P*(AS)P*(PST)P*TP*AP*GP*C)-3'), DNA-binding protein SATB1 | Authors: | Akutsu, Y, Kubota, T, Yamasaki, T, Yamasaki, K. | Deposit date: | 2019-12-02 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Enhanced affinity of racemic phosphorothioate DNA with transcription factor SATB1 arising from diastereomer-specific hydrogen bonds and hydrophobic contacts. Nucleic Acids Res., 48, 2020
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6LUE
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![BU of 6lue by Molmil](/molmil-images/mine/6lue) | Crystal structure of mouse Cryptochrome 1 in complex with compound KL201 | Descriptor: | 2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide, Cryptochrome-1 | Authors: | Miller, S, Aikawa, Y, Hirota, T. | Deposit date: | 2020-01-27 | Release date: | 2020-06-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals. Cell Chem Biol, 27, 2020
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5I5C
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![BU of 5i5c by Molmil](/molmil-images/mine/5i5c) | X-ray crystal structure of allo-Thr31-ShK | Descriptor: | GLYCEROL, Kappa-stichotoxin-She3a, LITHIUM ION, ... | Authors: | Dang, B, Kubota, T, Manda, K.l, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | Deposit date: | 2016-02-15 | Release date: | 2017-01-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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5I5B
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![BU of 5i5b by Molmil](/molmil-images/mine/5i5b) | quasi racemic structure of allo-Thr13-ShK and D-ShK | Descriptor: | D-ShK, GLYCEROL, Kappa-stichotoxin-She3a, ... | Authors: | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | Deposit date: | 2016-02-15 | Release date: | 2017-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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