6LFF
transcription factor SATB1 CUTr1 domain in complex with a phosphorothioate DNA
Summary for 6LFF
Entry DOI | 10.2210/pdb6lff/pdb |
Related | 2O49 2O4A |
Descriptor | DNA-binding protein SATB1, DNA (5'-D(*GP*(C7R)P*(PST)P*AP*AP*TP*AP*TP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*(AS)P*(PST)P*(AS)P*(PST)P*TP*AP*GP*C)-3'), ... (4 entities in total) |
Functional Keywords | dna-binding protein, dna modification, transcription factor, transcription, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 29323.99 |
Authors | Akutsu, Y.,Kubota, T.,Yamasaki, T.,Yamasaki, K. (deposition date: 2019-12-02, release date: 2020-04-01, Last modification date: 2023-11-22) |
Primary citation | Yamasaki, K.,Akutsu, Y.,Yamasaki, T.,Miyagishi, M.,Kubota, T. Enhanced affinity of racemic phosphorothioate DNA with transcription factor SATB1 arising from diastereomer-specific hydrogen bonds and hydrophobic contacts. Nucleic Acids Res., 48:4551-4561, 2020 Cited by PubMed: 32187371DOI: 10.1093/nar/gkaa170 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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