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7F4B

The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii.

Summary for 7F4B
Entry DOI10.2210/pdb7f4b/pdb
Descriptorhomoserine dehydrogenase, MAGNESIUM ION (3 entities in total)
Functional Keywordsheat-induced activation, oxidoreductase
Biological sourceSulfurisphaera tokodaii
Total number of polymer chains2
Total formula weight66871.60
Authors
Kurihara, E.,Kubota, T.,Watanabe, K.,Ogata, K.,Kaneko, R.,Oshima, T.,Yoshimune, K.,Goto, M. (deposition date: 2021-06-18, release date: 2022-06-22, Last modification date: 2023-11-29)
Primary citationKubota, T.,Kurihara, E.,Watanabe, K.,Ogata, K.,Kaneko, R.,Goto, M.,Ohshima, T.,Yoshimune, K.
Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase.
Commun Biol, 5:704-704, 2022
Cited by
PubMed: 35835834
DOI: 10.1038/s42003-022-03656-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

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