9ELY
 
 | | raiA RNA motif (Clostridium acetobutylicum) | | Descriptor: | raiA RNA | | Authors: | Kretsch, R.C, Wu, Y, Nye, G, Das, R, Chiu, W. | | Deposit date: | 2024-12-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Naturally ornate RNA-only complexes revealed by cryo-EM.
Nature, 2025
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9MCW
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8UYJ
 | | BtCoV-HKU5 5' proximal stem-loop 5, conformation 4 | | Descriptor: | BtCoV-HKU5 5' proximal stem-loop 5, conformation 4 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYS
 | | SARS-CoV-2 5' proximal stem-loop 5 | | Descriptor: | SARS-CoV-2 RNA SL5 domain. | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-14 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYL
 | | MERS 5' proximal stem-loop 5, conformation 2 | | Descriptor: | MERS 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYM
 | | MERS 5' proximal stem-loop 5, conformation 3 | | Descriptor: | MERS 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYK
 | | MERS 5' proximal stem-loop 5, conformation 1 | | Descriptor: | MERS 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYG
 | | BtCoV-HKU5 5' proximal stem-loop 5, conformation 2 | | Descriptor: | RNA (135-MER) | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYE
 | | BtCoV-HKU5 5' proximal stem-loop 5, conformation 1 | | Descriptor: | BtCoV-HKU5 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYP
 | | SARS-CoV-1 5' proximal stem-loop 5 | | Descriptor: | SARS-CoV-1 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-20 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.1 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9MDS
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9MEE
 | | GOLLD RNA nanocage (env-38) | | Descriptor: | GOLLD RNA nanocage | | Authors: | Kretsch, R.C, Wu, Y, Nye, G, Das, R, Chiu, W. | | Deposit date: | 2024-12-06 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Naturally ornate RNA-only complexes revealed by cryo-EM.
Nature, 2025
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9CBX
 | | Tetrahymena ribozyme with automatically identified water and magnesium ions | | Descriptor: | MAGNESIUM ION, RNA (387-MER) | | Authors: | Kretsch, R.C, Li, S, Pintilie, G, Palo, M.Z, Case, D.A, Das, R, Zhang, K, Chiu, W. | | Deposit date: | 2024-06-20 | | Release date: | 2024-11-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Complex water networks visualized by cryogenic electron microscopy of RNA.
Nature, 642, 2025
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9CBW
 | | Tetrahymena ribozyme with consensus water and magnesium ions | | Descriptor: | MAGNESIUM ION, RNA (387-MER) | | Authors: | Kretsch, R.C, Li, S, Pintilie, G, Palo, M.Z, Case, D.A, Das, R, Zhang, K, Chiu, W. | | Deposit date: | 2024-06-20 | | Release date: | 2024-11-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Complex water networks visualized by cryogenic electron microscopy of RNA.
Nature, 642, 2025
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9CBU
 | | Tetrahymena ribozyme with consensus water and magnesium ions | | Descriptor: | MAGNESIUM ION, RNA (387-MER) | | Authors: | Kretsch, R.C, Li, S, Pintilie, G, Palo, M.Z, Case, D.A, Das, R, Zhang, K, Chiu, W. | | Deposit date: | 2024-06-20 | | Release date: | 2024-11-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Complex water networks visualized by cryogenic electron microscopy of RNA.
Nature, 642, 2025
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9CBY
 | | Tetrahymena ribozyme with automatically identified water and magnesium ions | | Descriptor: | MAGNESIUM ION, RNA (387-MER) | | Authors: | Kretsch, R.C, Li, S, Pintilie, G, Palo, M.Z, Case, D.A, Das, R, Zhang, K, Chiu, W. | | Deposit date: | 2024-06-20 | | Release date: | 2024-11-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Complex water networks visualized by cryogenic electron microscopy of RNA.
Nature, 642, 2025
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9QAX
 | | The catalytic core with C2 symmetry of human telomerase dimer | | Descriptor: | Adrenocortical dysplasia protein homolog, DNA (5'-D(P*GP*TP*TP*AP*GP*GP*G)-3'), Histone H2A, ... | | Authors: | Balch, S, Sekne, Z, Franco-Echevarria, E, Ludzia, P, Kretsch, R.C, Sun, W, Yu, H, Ghanim, G.E, Sigurdur, T.R, Ding, Y, Das, R, Nguyen, T.H.D. | | Deposit date: | 2025-02-28 | | Release date: | 2025-07-16 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization.
Science, 389, 2025
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9QAZ
 | | Catalytic core 2 of dimeric human telomerase | | Descriptor: | Adrenocortical dysplasia protein homolog, DNA (5'-D(P*GP*TP*TP*AP*GP*GP*G)-3'), Histone H2A, ... | | Authors: | Balch, S, Sekne, Z, Franco-Echevarria, E, Ludzia, P, Kretsch, R.C, Sun, W, Yu, H, Ghanim, G.E, Sigurdur, T.R, Ding, Y, Das, R, Nguyen, T.H.D. | | Deposit date: | 2025-02-28 | | Release date: | 2025-07-16 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization.
Science, 389, 2025
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9QAY
 | | Catalytic core 1 of dimeric human telomerase | | Descriptor: | Adrenocortical dysplasia protein homolog, DNA (5'-D(P*GP*TP*TP*AP*GP*GP*G)-3'), Histone H2A, ... | | Authors: | Balch, S, Sekne, Z, Franco-Echevarria, E, Ludzia, P, Kretsch, R.C, Sun, W, Yu, H, Ghanim, G.E, Sigurdur, T.R, Ding, Y, Das, R, Nguyen, T.H.D. | | Deposit date: | 2025-02-28 | | Release date: | 2025-07-16 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization.
Science, 389, 2025
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9QB2
 | | H/ACA RNP protomer of human telomerase dimer | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | Authors: | Balch, S, Sekne, Z, Franco-Echevarria, E, Ludzia, P, Kretsch, R.C, Sun, W, Yu, H, Ghanim, G.E, Sigurdur, T.R, Ding, Y, Das, R, Nguyen, T.H.D. | | Deposit date: | 2025-02-28 | | Release date: | 2025-07-16 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization.
Science, 389, 2025
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9QB3
 | | Dimer structure of H/ACA RNP lobe of human telomerase | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | Authors: | Balch, S, Sekne, Z, Franco-Echevarria, E, Ludzia, P, Kretsch, R.C, Sun, W, Yu, H, Ghanim, G.E, Sigurdur, T.R, Ding, Y, Das, R, Nguyen, T.H.D. | | Deposit date: | 2025-02-28 | | Release date: | 2025-07-16 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization.
Science, 389, 2025
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6W4S
 | | Structure of apo human ferroportin in lipid nanodisc | | Descriptor: | Fab45D8 Heavy Chain, Fab45D8 Light Chain, Solute carrier family 40 member 1 | | Authors: | Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. | | Deposit date: | 2020-03-11 | | Release date: | 2020-09-09 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
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6WBV
 | | Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc | | Descriptor: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, COBALT (II) ION, Fab45D8 Heavy Chain, ... | | Authors: | Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. | | Deposit date: | 2020-03-27 | | Release date: | 2020-09-09 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
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6W4V
 | | Structure of anti-ferroportin Fab45D8 | | Descriptor: | 1,2-ETHANEDIOL, Fab45D8 Heavy Chain, Fab45D8 Light Chain | | Authors: | Billesboelle, C.B, Azumaya, C.M, Gonen, S, Powers, A, Kretsch, R.C, Schneider, S, Arvedson, T, Dror, R.O, Cheng, Y, Manglik, A. | | Deposit date: | 2020-03-11 | | Release date: | 2020-09-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
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