8PE1
| Crystal structure of Gel4 in complex with Nanobody 4 | Descriptor: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 4, ... | Authors: | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | Deposit date: | 2023-06-13 | Release date: | 2024-06-19 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 63, 2024
|
|
8PE2
| Crystal structure of Gel4 in complex with Nanobody 3 | Descriptor: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3, ... | Authors: | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | Deposit date: | 2023-06-13 | Release date: | 2024-06-19 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 63, 2024
|
|
2YGD
| Molecular architectures of the 24meric eye lens chaperone alphaB- crystallin elucidated by a triple hybrid approach | Descriptor: | ALPHA-CRYSTALLIN B CHAIN | Authors: | Braun, N, Zacharias, M, Peschek, J, Kastenmueller, A, Zou, J, Hanzlik, M, Haslbeck, M, Rappsilber, J, Buchner, J, Weinkauf, S. | Deposit date: | 2011-04-13 | Release date: | 2011-12-07 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Multiple Molecular Architectures of the Eye Lens Chaperone Alpha Beta-Crystallin Elucidated by a Triple Hybrid Approach Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4CZ3
| HP24wt derived from the villin headpiece subdomain | Descriptor: | VILLIN-1 | Authors: | Hocking, H, Haese, F, Madl, T, Zacharias, M, Rief, M, Zoldak, G. | Deposit date: | 2014-04-16 | Release date: | 2015-02-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Compact Native 24-Residue Supersecondary Structure Derived from the Villin Headpiece Subdomain. Biophys.J., 108, 2015
|
|
4CZ4
| HP24stab derived from the villin headpiece subdomain | Descriptor: | VILLIN-1 | Authors: | Hocking, H, Haese, F, Madl, T, Zacharias, M, Rief, M, Zoldak, G. | Deposit date: | 2014-04-16 | Release date: | 2015-02-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Compact Native 24-Residue Supersecondary Structure Derived from the Villin Headpiece Subdomain. Biophys.J., 108, 2015
|
|
8CRL
| Crystal structure of LplA1 in complex with the inhibitor C3 (Listeria monocytogenes) | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | Authors: | Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. | Deposit date: | 2023-03-08 | Release date: | 2023-06-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
8CRI
| Crystal structure of LplA1 in complex with lipoic acid (Listeria monocytogenes) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, LIPOIC ACID, ... | Authors: | Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. | Deposit date: | 2023-03-08 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
8CRJ
| Crystal structure of LplA1 in complex with lipoyl-AMP (Listeria monocytogenes) | Descriptor: | 1,2-ETHANEDIOL, 5'-O-[(R)-({5-[(3R)-1,2-DITHIOLAN-3-YL]PENTANOYL}OXY)(HYDROXY)PHOSPHORYL]ADENOSINE, GLYCEROL, ... | Authors: | Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. | Deposit date: | 2023-03-08 | Release date: | 2023-06-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
6SM1
| Wild type immunoglobulin light chain (WT-1) | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Immunoglobulin lambda variable 2-14, ... | Authors: | Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J. | Deposit date: | 2019-08-21 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation. Elife, 9, 2020
|
|
6SM2
| Mutant immunoglobulin light chain causing amyloidosis (Pat-1) | Descriptor: | Pat-1 | Authors: | Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J. | Deposit date: | 2019-08-21 | Release date: | 2020-03-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation. Elife, 9, 2020
|
|
4IQY
| Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2 | Descriptor: | MAGNESIUM ION, O-acetyl-ADP-ribose deacetylase MACROD2, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Jankevicius, G, Hassler, M, Golia, B, Rybin, V, Zacharias, M, Timinszky, G, Ladurner, A.G. | Deposit date: | 2013-01-14 | Release date: | 2013-03-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A family of macrodomain proteins reverses cellular mono-ADP-ribosylation. Nat.Struct.Mol.Biol., 20, 2013
|
|
4LAV
| Crystal Structure Analysis of FKBP52, Crystal Form II | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP4, SULFATE ION | Authors: | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | Deposit date: | 2013-06-20 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
|
|
4LAY
| Crystal Structure Analysis of FKBP52, Complex with I63 | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP4, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid | Authors: | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | Deposit date: | 2013-06-20 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
|
|
4LAW
| Crystal Structure Analysis of FKBP52, Crystal Form III | Descriptor: | DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase FKBP4 | Authors: | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | Deposit date: | 2013-06-20 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
|
|
4LAX
| Crystal Structure Analysis of FKBP52, Complex with FK506 | Descriptor: | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | Deposit date: | 2013-06-20 | Release date: | 2013-08-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.007 Å) | Cite: | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
|
|
6R9T
| Cryo-EM structure of autoinhibited human talin-1 | Descriptor: | Talin-1 | Authors: | Dedden, D, Schumacher, S, Zacharias, M, Biertumpfel, C, Mizuno, N. | Deposit date: | 2019-04-04 | Release date: | 2019-10-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | The Architecture of Talin1 Reveals an Autoinhibition Mechanism. Cell, 179, 2019
|
|
3DEL
| |
7OVT
| |
7ZKY
| |
7BGH
| |
1Z30
| NMR structure of the apical part of stemloop D from cloverleaf 1 of bovine enterovirus 1 RNA | Descriptor: | 5'-R(*GP*GP*CP*GP*UP*UP*CP*GP*UP*UP*AP*GP*AP*AP*CP*GP*UP*C)-3' | Authors: | Ihle, Y, Ohlenschlager, O, Duchardt, E, Ramachandran, R, Gorlach, M. | Deposit date: | 2005-03-10 | Release date: | 2005-04-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA Nucleic Acids Res., 33, 2005
|
|
7NE3
| Human TET2 in complex with favourable DNA substrate. | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*CP*AP*GP*GP*(5CM)P*GP*CP*CP*TP*G)-3'), ... | Authors: | Rafalski, D, Bochtler, M. | Deposit date: | 2021-02-03 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. Sci Adv, 8, 2022
|
|
7NE6
| Human TET2 in complex with unfavourable DNA substrate. | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*CP*AP*GP*GP*(5CM)P*GP*CP*CP*TP*G)-3'), ... | Authors: | Rafalski, D, Bochtler, M. | Deposit date: | 2021-02-03 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. Sci Adv, 8, 2022
|
|
3N26
| Cpn0482 : the arginine binding protein from the periplasm of chlamydia Pneumoniae | Descriptor: | ARGININE, Amino acid ABC transporter, periplasmic amino acid-binding protein | Authors: | Petit, P, Garcia, C, Vuillard, L, Soriani, M, Grandi, G, Marseilles Structural Genomics Program AFMB (MSGP), Marseilles Structural Genomics Program @ AFMB (MSGP) | Deposit date: | 2010-05-17 | Release date: | 2010-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Exploiting antigenic diversity for vaccine design: the Chlamydia ArtJ paradigm. J.Biol.Chem., 2010
|
|
6YHI
| Solution NMR Structure of APP G38L mutant TMD | Descriptor: | Amyloid-beta precursor protein G38L mutant | Authors: | Silber, M, Muhle-Goll, C. | Deposit date: | 2020-03-30 | Release date: | 2020-12-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Altered Hinge Conformations in APP Transmembrane Helix Mutants May Affect Enzyme-Substrate Interactions of gamma-Secretase. Acs Chem Neurosci, 11, 2020
|
|