8CRI
Crystal structure of LplA1 in complex with lipoic acid (Listeria monocytogenes)
Summary for 8CRI
Entry DOI | 10.2210/pdb8cri/pdb |
Related | 6JOM |
Descriptor | lipoate--protein ligase, LIPOIC ACID, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | lipoate, salvage, anti-infectives, drug development, ligase |
Biological source | Listeria monocytogenes |
Total number of polymer chains | 2 |
Total formula weight | 77238.81 |
Authors | Dienemann, J.-N.,Chen, S.-Y.,Hitzenberger, M.,Sievert, M.L.,Hacker, S.M.,Prigge, S.T.,Zacharias, M.,Groll, M.,Sieber, S.A. (deposition date: 2023-03-08, release date: 2023-06-07, Last modification date: 2023-08-02) |
Primary citation | Dienemann, J.N.,Chen, S.Y.,Hitzenberger, M.,Sievert, M.L.,Hacker, S.M.,Prigge, S.T.,Zacharias, M.,Groll, M.,Sieber, S.A. A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62:e202304533-e202304533, 2023 Cited by PubMed: 37249408DOI: 10.1002/anie.202304533 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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