1ZEQ
| 1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli | Descriptor: | Cation efflux system protein cusF | Authors: | Loftin, I.R, Franke, S, Roberts, S.A, Weichsel, A, Heroux, A, Montfort, W.R, Rensing, C, McEvoy, M.M. | Deposit date: | 2005-04-19 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A Novel Copper-Binding Fold for the Periplasmic Copper Resistance Protein CusF. Biochemistry, 44, 2005
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3F6P
| Crystal Structure of unphosphorelated receiver domain of YycF | Descriptor: | Transcriptional regulatory protein yycF | Authors: | Zhao, H, Tang, L. | Deposit date: | 2008-11-06 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Preliminary crystallographic studies of the regulatory domain of response regulator YycF from an essential two-component signal transduction system. Acta Crystallogr.,Sect.F, 65, 2009
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4QYZ
| Crystal structure of a CRISPR RNA-guided surveillance complex, Cascade, bound to a ssDNA target | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | Authors: | Mulepati, S, Bailey, S. | Deposit date: | 2014-07-26 | Release date: | 2014-09-03 | Last modified: | 2014-10-01 | Method: | X-RAY DIFFRACTION (3.0303 Å) | Cite: | Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target. Science, 345, 2014
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3VA5
| Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/V23A at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Caro, J.A, Nam, S.P, Heroux, A, Schlessman, J.L, Garcia-Moreno, E.B. | Deposit date: | 2011-12-28 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Pressure effects in proteins. To be Published
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4EVO
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3D8T
| Thermus thermophilus Uroporphyrinogen III Synthase | Descriptor: | ACETATE ION, Uroporphyrinogen-III synthase | Authors: | Schubert, H.L. | Deposit date: | 2008-05-23 | Release date: | 2008-08-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex. Biochemistry, 47, 2008
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3D8S
| Thermus thermophilus Uroporphyrinogen III Synthase | Descriptor: | GLYCEROL, Uroporphyrinogen-III synthase | Authors: | Schubert, H.L. | Deposit date: | 2008-05-23 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex. Biochemistry, 47, 2008
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3D8N
| Uroporphyrinogen III Synthase-Uroporphyringen III Complex | Descriptor: | 3,3',3'',3'''-[3,8,13,17-tetrakis(carboxymethyl)porphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, Uroporphyrinogen-III synthase | Authors: | Schubert, H.L. | Deposit date: | 2008-05-23 | Release date: | 2008-08-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex. Biochemistry, 47, 2008
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3D8R
| Thermus thermophilus Uroporphyrinogen III Synthase | Descriptor: | PHOSPHATE ION, Uroporphyrinogen-III synthase | Authors: | Schubert, H.L. | Deposit date: | 2008-05-23 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex. Biochemistry, 47, 2008
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4L2W
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3LZS
| Crystal Structure of HIV-1 CRF01_AE Protease in Complex with Darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease | Authors: | Schiffer, C.A, Bandaranayake, R.M. | Deposit date: | 2010-03-01 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways. J.Virol., 84, 2010
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3LZV
| Structure of Nelfinavir-resistant HIV-1 protease (D30N/N88D) in complex with Darunavir. | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 Protease, ... | Authors: | Schiffer, C.A, Kolli, M. | Deposit date: | 2010-03-01 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways. J.Virol., 84, 2010
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5UMR
| Crystal structure of N-terminal domain of human FACT complex subunit SSRP1 | Descriptor: | FACT complex subunit SSRP1 | Authors: | Su, D, Hu, Q, Thompson, J.R, Heroux, A, Botuyan, M.V, Mer, G. | Deposit date: | 2017-01-29 | Release date: | 2018-01-31 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Crystal structure of N-terminal domain of human FACT complex subunit SSRP1 To Be Published
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3NPN
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3LZU
| Crystal Structure of a Nelfinavir Resistant HIV-1 CRF01_AE Protease variant (N88S) in Complex with the Protease Inhibitor Darunavir. | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease | Authors: | Schiffer, C.A, Bandaranayake, R.M. | Deposit date: | 2010-03-01 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways. J.Virol., 84, 2010
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5UMU
| Crystal structure of the middle double PH domain of human FACT complex subunit SPT16 | Descriptor: | ACETATE ION, FACT complex subunit SPT16, FORMIC ACID | Authors: | Hu, Q, Thompson, J.R, Heroux, A, Su, D, Botuyan, M.V, Mer, G. | Deposit date: | 2017-01-29 | Release date: | 2018-01-31 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Crystal structure of the middle double PH domain of human FACT complex subunit SPT16 To Be Published
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3NPQ
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3OSS
| The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system | Descriptor: | CALCIUM ION, CHLORIDE ION, TYPE 2 SECRETION SYSTEM, ... | Authors: | Korotkov, K.V, Pruneda, J, Hol, W.G.J. | Deposit date: | 2010-09-09 | Release date: | 2011-08-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structural and functional studies on the interaction of GspC and GspD in the type II secretion system. Plos Pathog., 7, 2011
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1Y0O
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1OMO
| alanine dehydrogenase dimer w/bound NAD (archaeal) | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, alanine dehydrogenase | Authors: | Gallagher, D.T, Smith, N.N, Holden, M.J, Schroeder, I, Monbouquette, H.G. | Deposit date: | 2003-02-25 | Release date: | 2004-07-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin. J.Mol.Biol., 342, 2004
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8P5I
| Kinase domain of mutant human ULK1 in complex with compound XMD-17-51 | Descriptor: | 5,11-dimethyl-2-[(1-piperidin-4-ylpyrazol-4-yl)amino]pyrimido[4,5-b][1,4]benzodiazepin-6-one, GLYCEROL, MAGNESIUM ION, ... | Authors: | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | Deposit date: | 2023-05-24 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.829 Å) | Cite: | Crystal structures of ULK1 in complex with KCGS compounds To Be Published
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8P5G
| Kinase domain of wild type human ULK1 in complex with compound CCT241533 | Descriptor: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, SODIUM ION, ... | Authors: | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | Deposit date: | 2023-05-24 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.019 Å) | Cite: | Crystal structures of ULK1 in complex with KCGS compounds To Be Published
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8P5L
| Kinase domain of mutant human ULK1 in complex with compound MRT67307 | Descriptor: | MAGNESIUM ION, N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, Serine/threonine-protein kinase ULK1 | Authors: | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | Deposit date: | 2023-05-24 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.836 Å) | Cite: | Crystal structures of ULK1 in complex with KCGS compounds To Be Published
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8P5J
| Kinase domain of mutant human ULK1 in complex with compound WZ4003 | Descriptor: | MAGNESIUM ION, SODIUM ION, Serine/threonine-protein kinase ULK1, ... | Authors: | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | Deposit date: | 2023-05-24 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.164 Å) | Cite: | Crystal structures of ULK1 in complex with KCGS compounds To Be Published
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8P5H
| Kinase domain of mutant human ULK1 in complex with compound CCT241533 | Descriptor: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, SODIUM ION, ... | Authors: | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | Deposit date: | 2023-05-24 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.941 Å) | Cite: | Crystal structures of ULK1 in complex with KCGS compounds To Be Published
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