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5T85
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BU of 5t85 by Molmil
Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidylglycerol (06:0 PG)
Descriptor: (2S)-3-{[(R)-{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2016-09-06
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.373 Å)
Cite:Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T6S
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BU of 5t6s by Molmil
Crystal structure of the A/Shanghai/2/2013 (H7N9) influenza virus hemagglutinin in complex with the antiviral drug arbidol
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2016-09-01
Release date:2017-01-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TH1
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BU of 5th1 by Molmil
Crystal structure of H10 hemagglutinin mutant (K158aA-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 6'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Wilson, I.A.
Deposit date:2016-09-28
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5THF
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BU of 5thf by Molmil
Crystal structure of H3 hemagglutinin with insertion of two amino acids in the 150-loop from the A/Hong Kong/1/1968 (H3N2) influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Wilson, I.A.
Deposit date:2016-09-29
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5THB
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BU of 5thb by Molmil
Crystal structure of H10 hemagglutinin mutant (T193D-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Wilson, I.A.
Deposit date:2016-09-29
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5TGV
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BU of 5tgv by Molmil
Crystal structure of H10 hemagglutinin mutant (K158aA-D193T-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Wilson, I.A.
Deposit date:2016-09-28
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.974 Å)
Cite:The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5U7G
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BU of 5u7g by Molmil
Crystal Structure of the Catalytic Core of CBP
Descriptor: CREB-binding protein, ZINC ION
Authors:Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E.
Deposit date:2016-12-12
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UEI
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BU of 5uei by Molmil
Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo)
Descriptor: CHLORIDE ION, GLYCEROL, O13
Authors:Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A.
Deposit date:2017-01-02
Release date:2017-10-18
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
5UF4
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BU of 5uf4 by Molmil
Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 with LNnT bound
Descriptor: O13, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Cooper, M.D, Herrin, B.R, Wilson, I.A.
Deposit date:2017-01-03
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
5TZL
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BU of 5tzl by Molmil
Structure of transthyretin in complex with the kinetic stabilizer 201
Descriptor: 4-(7-chloro-1,3-benzoxazol-2-yl)-2,6-diiodophenol, Transthyretin
Authors:Connelly, S, Mortenson, D.E, Choi, S, Wilson, I.A, Powers, E.T, Kelly, J.W, Johnson, S.M.
Deposit date:2016-11-21
Release date:2017-06-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5U65
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BU of 5u65 by Molmil
Camel Nanobody VHH-5
Descriptor: SULFATE ION, VHH-5
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2016-12-07
Release date:2017-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Sci Rep, 7, 2017
5UFB
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BU of 5ufb by Molmil
Crystal Structure of Variable Lymphocyte Receptor (VLR) Tn4-22 (Apo)
Descriptor: Tn4-22
Authors:Collins, B.C, Gunn, R.J, McKitrick, T.R, Cummings, R.D, Cooper, M.D, Herrin, B.R, Wilson, I.A.
Deposit date:2017-01-04
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.844 Å)
Cite:Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
5UFF
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BU of 5uff by Molmil
Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 with Fucose(alpha-1-2)Lactose bound
Descriptor: RBC36, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Collins, B.C, Gunn, R.J, McKitrick, T.R, Herrin, B.R, Cummings, R.D, Cooper, M.D, Wilson, I.A.
Deposit date:2017-01-04
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.137 Å)
Cite:Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
4R26
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BU of 4r26 by Molmil
Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain
Authors:Garces, F, Kong, L, Wilson, I.A.
Deposit date:2014-08-08
Release date:2014-10-08
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.4969 Å)
Cite:Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
4R2G
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BU of 4r2g by Molmil
Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Garces, F, Wilson, I.A.
Deposit date:2014-08-11
Release date:2014-10-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
4RBP
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BU of 4rbp by Molmil
Crystal structure of HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomanose
Descriptor: Fab 2G12 heavy chain, Fab 2G12 light chain, GLYCEROL, ...
Authors:Stanfield, R.L, Wilson, I.A, De Castro, C, Marzaioli, A.M, Pantophlet, R.
Deposit date:2014-09-12
Release date:2014-11-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose.
Glycobiology, 25, 2015
4RQQ
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BU of 4rqq by Molmil
Crystal structure of human Fab PGDM1400, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: Human anti-HIV-1 antibody PGDM1400 heavy chain, Human anti-HIV-1 antibody PGDM1400 light chain
Authors:Julien, J.-P, Wilson, I.A.
Deposit date:2014-11-04
Release date:2014-11-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RNR
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BU of 4rnr by Molmil
Crystal structure of broadly neutralizing anti-HIV antibody PGT130
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain
Authors:Kong, L, Wilson, I.A.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
4RQS
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BU of 4rqs by Molmil
Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kong, L, Wilson, I.A, Kwong, P.D.
Deposit date:2014-11-05
Release date:2014-12-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.493 Å)
Cite:Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
7LA7
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BU of 7la7 by Molmil
O6 variable lymphocyte receptor ectodomain
Descriptor: PHOSPHATE ION, variable lymphocyte receptor O6
Authors:Bernard, S.M, Wilson, I.A.
Deposit date:2021-01-06
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55100727 Å)
Cite:Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins.
Commun Biol, 4, 2021
7LA8
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BU of 7la8 by Molmil
O6 variable lymphocyte receptor ectodomain bound to 3-HSO3-Gal-4GlcNAc
Descriptor: 3-O-sulfo-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BIOTIN, O6 variable lymphocyte receptor, ...
Authors:Bernard, S.M, Wilson, I.A.
Deposit date:2021-01-06
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8965 Å)
Cite:Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins.
Commun Biol, 4, 2021
7LQ7
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BU of 7lq7 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ...
Authors:Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2021-02-13
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.
Sci Transl Med, 13, 2021
5YL9
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BU of 5yl9 by Molmil
1.86 Angstrom crystal structure of human Coronavirus 229E fusion core
Descriptor: Spike glycoprotein
Authors:Yang, B, Yan, L, Meng, B, WIlson, I.A.
Deposit date:2017-10-17
Release date:2018-09-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.861 Å)
Cite:Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86 angstrom resolution
Acta Crystallogr D Struct Biol, 74, 2018
5ZUV
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BU of 5zuv by Molmil
Crystal Structure of the Human Coronavirus 229E HR1 motif in complex with pan-CoVs inhibitor EK1
Descriptor: CHLORIDE ION, Spike glycoprotein,Spike glycoprotein,inhibitor EK1
Authors:Yan, L, Yang, B, Wilson, I.A.
Deposit date:2018-05-08
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019
5ZVM
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BU of 5zvm by Molmil
Crystal Structure of the Human Coronavirus SARS HR1 motif in complex with pan-CoVs inhibitor EK1
Descriptor: Spike glycoprotein, pan-CoV inhibitory peptide EK1
Authors:Yan, L, Yang, B, Wilson, I.A.
Deposit date:2018-05-11
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5, 2019

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數據於2024-06-26公開中

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