8VQN

Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6R

This is a non-PDB format compatible entry.

Summary for 8VQN

• Entry DOI: 10.2210/pdb8vqn/pdb
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: h1n1, antibody, hemagglutinin, viral protein
• Biological source: Influenza A virus (A/Puerto Rico/8/1934(H1N1)); More
• Total number of polymer chains: 2
• Total formula weight: 62777.06

Authors

Lin, T.H.,Zhu, Y.,Wilson, I.A. (deposition date: 2024-01-18, release date: 2024-06-05)

• Primary citation: Kitamura, S.,Lin, T.H.,Lee, C.D.,Takamura, A.,Kadam, R.U.,Zhang, D.,Zhu, X.,Dada, L.,Nagai, E.,Yu, W.,Yao, Y.,Sharpless, K.B.,Wilson, I.A.,Wolan, D.W.; Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry.; Proc.Natl.Acad.Sci.USA, 121:e2310677121-e2310677121, 2024; PubMed: 38753503; DOI: 10.1073/pnas.2310677121

Experimental method

X-RAY DIFFRACTION (2.21 Å)