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6M8B
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BU of 6m8b by Molmil
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with kaempferol
Descriptor: 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase
Authors:Wang, H, Shears, S.B.
Deposit date:2018-08-21
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
J. Med. Chem., 62, 2019
8H3T
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BU of 8h3t by Molmil
The crystal structure of AlpH
Descriptor: AlpH, GLYCEROL
Authors:Zhao, Y, Li, M, Jiang, M, Pan, L.F.
Deposit date:2022-10-09
Release date:2023-09-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.866 Å)
Cite:O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis.
Nat Commun, 14, 2023
6M1V
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BU of 6m1v by Molmil
Crystal structure of post fusion core of 2019-nCoV S2 subunit
Descriptor: Spike protein S2,Spike protein S2
Authors:Sun, H, Song, H, Wang, Q.
Deposit date:2020-02-26
Release date:2020-06-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of HCoV-19 fusion core and an effective inhibition peptide against virus entry.
Emerg Microbes Infect, 9, 2020
6M8C
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BU of 6m8c by Molmil
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with isorhamnetin
Descriptor: Inositol polyphosphate multikinase,Inositol polyphosphate multikinase, isorhamnetin
Authors:Wang, H, Shears, S.B.
Deposit date:2018-08-21
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
J. Med. Chem., 62, 2019
6M8E
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BU of 6m8e by Molmil
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with rhamnetin
Descriptor: 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase
Authors:Wang, H, Shears, S.B.
Deposit date:2018-08-21
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
J. Med. Chem., 62, 2019
6M8A
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BU of 6m8a by Molmil
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with luteolin
Descriptor: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase
Authors:Wang, H, Shears, S.B.
Deposit date:2018-08-21
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
J. Med. Chem., 62, 2019
3SHQ
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BU of 3shq by Molmil
Crystal Structure of UBLCP1
Descriptor: MAGNESIUM ION, UBLCP1
Authors:Xiao, J, Engel, J.L.
Deposit date:2011-06-16
Release date:2011-10-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity.
Proc.Natl.Acad.Sci.USA, 108, 2011
6MK8
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BU of 6mk8 by Molmil
NMR structure of Database designed and improved anti-Staphylococcal peptide DFT503 bound to micelles
Descriptor: Anti-Staphylococcal peptide DFT503
Authors:Wang, G.
Deposit date:2018-09-25
Release date:2019-06-19
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens.
Proc.Natl.Acad.Sci.USA, 116, 2019
6M88
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BU of 6m88 by Molmil
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with myricetin
Descriptor: 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Inositol polyphosphate multikinase,Inositol polyphosphate multikinase
Authors:Wang, H, Shears, S.B.
Deposit date:2018-08-21
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
J. Med. Chem., 62, 2019
2G46
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BU of 2g46 by Molmil
structure of vSET in complex with meK27 H3 Pept. and cofactor product SAH
Descriptor: PBCV-1 histone H3-Lys 27 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, meK27 H3 Peptide
Authors:Qian, C.M, Zheng, L, Zhou, M.M.
Deposit date:2006-02-21
Release date:2006-12-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase.
J.Mol.Biol., 359, 2006
7WGB
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BU of 7wgb by Molmil
Neutral Omicron Spike Trimer in complex with ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Cui, Z.
Deposit date:2021-12-28
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron.
Cell, 185, 2022
7WG8
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BU of 7wg8 by Molmil
Delta Spike Trimer(3 RBD Down)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Cui, Z.
Deposit date:2021-12-28
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron.
Cell, 185, 2022
5ZMN
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BU of 5zmn by Molmil
Sulfur binding domain and SRA domain of ScoMcrA complexed with phosphorothioated DNA
Descriptor: DNA (5'-D(*CP*CP*CP*GP*(GS)P*CP*CP*GP*GP*G)-3'), SULFATE ION, Uncharacterized protein McrA
Authors:Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X.
Deposit date:2018-04-04
Release date:2018-09-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structural basis for the recognition of sulfur in phosphorothioated DNA.
Nat Commun, 9, 2018
5ZMM
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BU of 5zmm by Molmil
Structure of the Type IV phosphorothioation-dependent restriction endonuclease ScoMcrA
Descriptor: SULFATE ION, Uncharacterized protein McrA, ZINC ION
Authors:Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X.
Deposit date:2018-04-04
Release date:2018-09-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural basis for the recognition of sulfur in phosphorothioated DNA.
Nat Commun, 9, 2018
4OU6
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BU of 4ou6 by Molmil
Crystal structure of DnaT84-153-dT10 ssDNA complex form 1
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Primosomal protein 1
Authors:Liu, Z, Chen, P, Niu, L, Teng, M, Li, X.
Deposit date:2014-02-15
Release date:2014-08-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode.
Nucleic Acids Res., 42, 2014
7JJJ
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BU of 7jjj by Molmil
Structure of SARS-CoV-2 3Q-2P full-length dimers of spike trimers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bangaru, S, Turner, H.L, Ozorowski, G, Antanasijevic, A, Ward, A.B.
Deposit date:2020-07-26
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate.
Science, 370, 2020
4OU7
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BU of 4ou7 by Molmil
Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Primosomal protein 1
Authors:Liu, Z, Chen, P, Niu, L, Teng, M, Li, X.
Deposit date:2014-02-15
Release date:2014-08-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Crystal structure of DnaT84-153-dT10 ssDNA complex reveals a novel single-stranded DNA binding mode.
Nucleic Acids Res., 42, 2014
4OUS
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BU of 4ous by Molmil
Crystal structure of zebrafish Caprin-2 C1q domain
Descriptor: CALCIUM ION, Caprin-2
Authors:Song, X, Li, L.
Deposit date:2014-02-18
Release date:2014-10-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
6A7A
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BU of 6a7a by Molmil
AKR1C1 complexed with new inhibitor with novel scaffold
Descriptor: (4R)-6-amino-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, X, Zhao, Y, Zhang, H, Chen, Y.
Deposit date:2018-07-02
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors.
Bioorg.Med.Chem., 26, 2018
7XXY
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BU of 7xxy by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein with lactose
Descriptor: Galectin-10/Charcot-Leyden crystal protein, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.Y.
Deposit date:2022-05-31
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXW
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BU of 7xxw by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with glycerol
Descriptor: GLYCEROL, Galectin
Authors:Su, J.Y.
Deposit date:2022-05-31
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXV
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BU of 7xxv by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with lactose
Descriptor: Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.Y.
Deposit date:2022-05-31
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXU
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BU of 7xxu by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein
Descriptor: Galectin
Authors:Su, J.Y.
Deposit date:2022-05-31
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXX
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BU of 7xxx by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein
Descriptor: Galectin-10/Charcot-Leyden crystal protein
Authors:Su, J.Y.
Deposit date:2022-05-31
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXZ
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BU of 7xxz by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein with glycerol
Descriptor: GLYCEROL, Galectin-10/Charcot-Leyden crystal protein
Authors:Su, J.Y.
Deposit date:2022-05-31
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023

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數據於2024-07-10公開中

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