5WJL
| Crystal Structure of HLA-A*11:01 with GTS1 peptide | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, GTS1 peptide, ... | Authors: | Gras, S, Rossjohn, J. | Deposit date: | 2017-07-23 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response. Nat. Immunol., 18, 2017
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7DPM
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-12-20 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.304 Å) | Cite: | Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV. Mabs, 13, 2021
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5WJN
| Crystal Structure of HLA-A*11:01-GTS3 | Descriptor: | Beta-2-microglobulin, GTS3 peptide, HLA class I histocompatibility antigen, ... | Authors: | Gras, S, Rossjohn, J. | Deposit date: | 2017-07-23 | Release date: | 2017-09-20 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response. Nat. Immunol., 18, 2017
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6YIZ
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4G3K
| Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state | Descriptor: | Transcriptional regulator nlh1 | Authors: | Wemmer, D.E, Batchelor, J.D, Wang, A, Lee, P, Doucleff, M. | Deposit date: | 2012-07-14 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus J.Mol.Biol., 425, 2013
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4G3W
| Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state | Descriptor: | Transcriptional regulator nlh1 | Authors: | Batchelor, J.D, Wang, A, Lee, P, Doucleff, M, Wemmer, D.E. | Deposit date: | 2012-07-15 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus J.Mol.Biol., 425, 2013
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4G3V
| Crystal structure of A. Aeolicus nlh2 gaf domain in an inactive state | Descriptor: | CHLORIDE ION, Transcriptional regulator nlh2 | Authors: | Batchelor, J.D, Lee, P, Wang, A, Doucleff, M, Wemmer, D.E. | Deposit date: | 2012-07-15 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus J.Mol.Biol., 425, 2013
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4RBW
| Crystal structure of human alpha-defensin 5, HD5 (Thr7Arg Glu21Arg mutant) | Descriptor: | CHLORIDE ION, Defensin-5, SULFATE ION | Authors: | Pazgier, M, Gohain, N, Tolbert, W.D. | Deposit date: | 2014-09-13 | Release date: | 2015-07-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Design of a potent antibiotic peptide based on the active region of human defensin 5. J.Med.Chem., 58, 2015
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6SWA
| Mus musculus brain neocortex ribosome 60S bound to Ebp1 | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kraushar, M.L, Sprink, T. | Deposit date: | 2019-09-20 | Release date: | 2020-09-30 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. Mol.Cell, 81, 2021
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7X08
| S protein of SARS-CoV-2 in complex with 2G1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | Authors: | Guo, Y.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2022-02-21 | Release date: | 2022-03-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD. Cell Discov, 8, 2022
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5W4R
| Structure of RORgt bound to a tertiary alcohol | Descriptor: | 1-{4-[(R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]piperidin-1-yl}ethan-1-one, Nuclear receptor ROR-gamma | Authors: | Spurlino, J. | Deposit date: | 2017-06-12 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | 6-Substituted quinolines as ROR gamma t inverse agonists. Bioorg. Med. Chem. Lett., 27, 2017
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7C6P
| Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid | Descriptor: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4 | Authors: | Li, J, Yu, K, Luo, Y, Zheng, W, Liang, W, Zhu, J. | Deposit date: | 2020-05-22 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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7C2Z
| Bromodomain-containing 4 BD1 in complex with 3',4',7,8-Tetrahydroxyflavone | Descriptor: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4, FORMIC ACID | Authors: | Li, J, Zhu, J. | Deposit date: | 2020-05-10 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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5W4V
| Structure of RORgt bound to a tertiary alcohol | Descriptor: | (R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol, Nuclear receptor ROR-gamma | Authors: | Spurlino, J, Hars, U. | Deposit date: | 2017-06-13 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | 6-Substituted quinolines as ROR gamma t inverse agonists. Bioorg. Med. Chem. Lett., 27, 2017
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8FE6
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8FE7
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8FUF
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6UF2
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4Z58
| HipB-O3 20mer complex | Descriptor: | Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*TP*AP*CP*GP*GP*GP*AP*TP*AP*A)-3') | Authors: | Min, J, Brennan, R.G, Schumacher, M.A. | Deposit date: | 2015-04-02 | Release date: | 2016-07-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism on hipBA gene regulation. To be published
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7LT3
| NHEJ Long-range synaptic complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (30-MER), DNA (31-MER), ... | Authors: | He, Y, Chen, S. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of long-range to short-range synaptic transition in NHEJ. Nature, 593, 2021
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7OU1
| Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MP2) | Descriptor: | 1,2-ETHANEDIOL, L-asparaginase, ZINC ION | Authors: | Imiolczyk, B, Loch, J.I, Gilski, M, Jaskolski, M. | Deposit date: | 2021-06-10 | Release date: | 2021-11-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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7OZ6
| Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MC) | Descriptor: | DI(HYDROXYETHYL)ETHER, L-asparaginase, ZINC ION | Authors: | Gilski, M, Loch, J.I, Imiolczyk, B, Jaskolski, M. | Deposit date: | 2021-06-25 | Release date: | 2021-11-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.757 Å) | Cite: | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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7OS6
| Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MP1) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | Authors: | Loch, J.I, Imiolczyk, B, Gilski, M, Jaskolski, M. | Deposit date: | 2021-06-07 | Release date: | 2021-11-24 | Last modified: | 2023-04-26 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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7OS3
| Crystal structure of Rhizobium etli inducible L-asparaginase ReAV solved by S-SAD (orthorhombic form START) | Descriptor: | CHLORIDE ION, L-asparaginase II protein, ZINC ION | Authors: | Gilski, M, Loch, J.I, Imiolczyk, B, Jaskolski, M. | Deposit date: | 2021-06-07 | Release date: | 2021-11-24 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.177 Å) | Cite: | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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7OS5
| Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (orthorhombic form OP) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, L-asparaginase, ... | Authors: | Loch, J.I, Imiolczyk, B, Gilski, M, Jaskolski, M. | Deposit date: | 2021-06-07 | Release date: | 2021-11-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.293 Å) | Cite: | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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