5WT9
| Complex structure of PD-1 and nivolumab-Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Nivolumab, Light Chain of Nivolumab, ... | Authors: | Tan, S, Zhang, H, Chai, Y, Song, H, Tong, Z, Wang, Q, Qi, J, Wong, G, Zhu, X, Liu, W.J, Gao, S, Wang, Z, Shi, Y, Yang, F, Gao, G.F, Yan, J. | Deposit date: | 2016-12-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | An unexpected N-terminal loop in PD-1 dominates binding by nivolumab. Nat Commun, 8, 2017
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4KON
| The structure of hemagglutinin from avian-origin H7N9 influenza virus in complex with human receptor analog 6'SLNLN (NeuAcα2-6Galβ1-4GlcNAcβ1-3Galβ1-4Glc) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-05-12 | Release date: | 2013-11-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
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4LCX
| The structure of hemagglutinin from avian-origin H7N9 influenza virus (A/Shanghai/1/2013) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2 | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-06-24 | Release date: | 2013-11-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.094 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
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1Q67
| Crystal structure of Dcp1p | Descriptor: | Decapping protein involved in mRNA degradation-Dcp1p | Authors: | She, M, Decker, C.J, Liu, Y, Chen, N, Parker, R, Song, H. | Deposit date: | 2003-08-12 | Release date: | 2004-03-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of Dcp1p and its functional implications in mRNA decapping Nat.Struct.Mol.Biol., 11, 2004
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4LKG
| The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with avian receptor analog 3'SLNLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-07-07 | Release date: | 2013-11-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.994 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LKK
| The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with human receptor analog 6'SLNLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, hemagglutinin | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-07-07 | Release date: | 2013-11-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.491 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LKJ
| The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with avian receptor analog 3'SLNLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-07-07 | Release date: | 2013-11-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LKH
| The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with human receptor analog 6'SLNLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-07-07 | Release date: | 2013-11-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.099 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LKI
| The structure of hemagglutinin L226Q mutant from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-07-07 | Release date: | 2013-11-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4KOM
| The structure of hemagglutinin from avian-origin H7N9 influenza virus in complex with avian receptor analog 3'SLNLN (NeuAcα2-3Galβ1-4GlcNAcβ1-3Galβ1-4Glc) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-05-12 | Release date: | 2013-11-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
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4KOL
| The structure of hemagglutinin from avian-origin H7N9 influenza virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2 | Authors: | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | Deposit date: | 2013-05-12 | Release date: | 2013-11-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.799 Å) | Cite: | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
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1R5O
| crystal structure analysis of sup35 complexed with GMPPNP | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Kong, C, Song, H. | Deposit date: | 2003-10-11 | Release date: | 2004-05-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe Mol.Cell, 14, 2004
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5JXE
| Human PD-1 ectodomain complexed with Pembrolizumab Fab | Descriptor: | Pembrolizumab Fab heavy chain, Pembrolizumab Fab light chain, Programmed cell death protein 1 | Authors: | Na, Z, Bharath, S.R, Song, H. | Deposit date: | 2016-05-13 | Release date: | 2016-08-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab. Cell Res., 27, 2017
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5WZ1
| Crystal structure of Zika virus NS5 methyltransferase bound to S-adenosyl-L-methionine | Descriptor: | NS5 methyltransferase, S-ADENOSYLMETHIONINE | Authors: | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | Deposit date: | 2017-01-16 | Release date: | 2017-03-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.507 Å) | Cite: | The crystal structure of Zika virus NS5 reveals conserved drug targets. EMBO J., 36, 2017
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5WZ2
| Crystal structure of Zika virus NS5 methyltransferase bound to SAM and RNA analogue (m7GpppA) | Descriptor: | NS5 MTase, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYLMETHIONINE | Authors: | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | Deposit date: | 2017-01-16 | Release date: | 2017-03-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of Zika virus NS5 reveals conserved drug targets. EMBO J., 36, 2017
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7TRC
| Human telomerase H/ACA RNP at 3.3 Angstrom | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRD
| Human telomerase catalytic core structure at 3.3 Angstrom | Descriptor: | Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRF
| Human telomerase catalytic core RNP with H2A/H2B | Descriptor: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRE
| Human telomerase catalytic core with shelterin protein TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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2JOO
| The NMR Solution Structure of Recombinant RGD-hirudin | Descriptor: | Hirudin variant-1 | Authors: | Song, X, Mo, W, Liu, X, Yan, X, Song, H, Dai, L. | Deposit date: | 2007-03-14 | Release date: | 2008-03-18 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The NMR solution structure of recombinant RGD-hirudin Biochem.Biophys.Res.Commun., 360, 2007
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4NG2
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4OWX
| Structural basis of SOSS1 in complex with a 12nt ssDNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Integrator complex subunit 3, SOSS complex subunit B1 | Authors: | Ren, W, Sun, Q, Tang, X, Song, H. | Deposit date: | 2014-02-04 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA. Cell Rep, 6, 2014
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4OWT
| Structural basis of SOSS1 complex assembly | Descriptor: | Integrator complex subunit 3, SOSS complex subunit B1, SOSS complex subunit C | Authors: | Ren, W, Sun, Q, Tang, X, Song, H. | Deposit date: | 2014-02-03 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA. Cell Rep, 6, 2014
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4OWW
| Structural basis of SOSS1 in complex with a 35nt ssDNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Integrator complex subunit 3, SOSS complex subunit B1, ... | Authors: | Ren, W, Sun, Q, Tang, X, Song, H. | Deposit date: | 2014-02-04 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA. Cell Rep, 6, 2014
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1XMM
| Structure of human Dcps bound to m7GDP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ... | Authors: | Chen, N, Song, H. | Deposit date: | 2004-10-04 | Release date: | 2005-03-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping. J.Mol.Biol., 347, 2005
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