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6V9O
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BU of 6v9o by Molmil
Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Descriptor: 3-(phenylsulfonyl)benzene-1-sulfonamide, FORMIC ACID, GLYCEROL, ...
Authors:Phan, J, Fesik, S.W.
Deposit date:2019-12-13
Release date:2020-12-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
To Be Published
6FK5
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BU of 6fk5 by Molmil
Structure of 3' phosphatase NExo (D146N) from Neisseria bound to DNA substrate in presence of magnesium ion
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*CP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*AP*GP*A)-3'), MAGNESIUM ION, ...
Authors:Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S.
Deposit date:2018-01-23
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
6VSJ
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BU of 6vsj by Molmil
Cryo-electron microscopy structure of mouse coronavirus spike protein complexed with its murine receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, Spike glycoprotein
Authors:Shang, J, Wan, Y.S, Liu, C, Yount, B, Gully, K, Yang, Y, Auerbach, A, Peng, G.Q, Baric, R, Li, F.
Deposit date:2020-02-11
Release date:2020-03-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.
Plos Pathog., 16, 2020
6FKE
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BU of 6fke by Molmil
Structure of 3' phosphatase NExo (D146N) from Neisseria bound to product DNA hairpin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*A)-3'), Exodeoxyribonuclease III, ...
Authors:Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S.
Deposit date:2018-01-23
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
6FK4
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BU of 6fk4 by Molmil
Structure of 3' phosphatase NExo (WT) from Neisseria bound to DNA substrate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*GP*CP*TP*AP*GP*CP*GP*AP*AP*GP*CP*TP*AP*GP*A)-3'), Exodeoxyribonuclease III
Authors:Silhan, J, Zhao, Q, Boura, E, Thomson, H, Foster, A, Tang, C.M, Freemont, P.S, Baldwin, G.S.
Deposit date:2018-01-23
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res., 46, 2018
6VW1
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BU of 6vw1 by Molmil
Structure of SARS-CoV-2 chimeric receptor-binding domain complexed with its receptor human ACE2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shang, J, Ye, G, Shi, K, Wan, Y.S, Aihara, H, Li, F.
Deposit date:2020-02-18
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural basis of receptor recognition by SARS-CoV-2.
Nature, 581, 2020
1K73
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BU of 1k73 by Molmil
Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
Descriptor: 23S RRNA, 5S RRNA, ANISOMYCIN, ...
Authors:Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-10-18
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1XG7
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BU of 1xg7 by Molmil
Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus
Descriptor: hypothetical protein
Authors:Chang, J, Zhao, M, Horanyi, P, Xu, H, Yang, H, Liu, Z.-J, Chen, L, Zhou, W, Habel, J, Tempel, W, Lee, D, Lin, D, Chang, S.-H, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Chen, C.-Y, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-16
Release date:2004-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus
To be published
5Y6P
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BU of 5y6p by Molmil
Structure of the phycobilisome from the red alga Griffithsia pacifica
Descriptor: ApcD, ApcF, LC, ...
Authors:Zhang, J, Ma, J.F, Liu, D.S, Sun, S, Sui, S.F.
Deposit date:2017-08-13
Release date:2017-11-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of phycobilisome from the red alga Griffithsia pacifica
Nature, 551, 2017
8K1I
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BU of 8k1i by Molmil
Crystal structure of arabinose dehydrogenase from Candida auris
Descriptor: NADP-dependent oxidoreductase domain-containing protein
Authors:Zhang, J, Bai, X, He, S.R, Zhao, Z.D.
Deposit date:2023-07-11
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of arabinose dehydrogenase from Candida auris
To Be Published
8TBY
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BU of 8tby by Molmil
Apo Bcs1, unsymmetrized
Descriptor: Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-29
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T5U
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BU of 8t5u by Molmil
ATP-1 state of Bcs1 (C7 symmetrized)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-14
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8OIX
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BU of 8oix by Molmil
CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor Salinosporamid A
Descriptor: (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE, Family T1, proteasome alpha subunit, ...
Authors:Silhan, J, Fajtova, P, Boura, E.
Deposit date:2023-03-23
Release date:2024-04-10
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Tv20S proteasome in the complex with marizomib
To Be Published
8T14
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BU of 8t14 by Molmil
ADP-bound Bcs1 (C7 symmetrized)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-01
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T7U
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BU of 8t7u by Molmil
ADP-bound Bcs1 (unsymmetrized)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-21
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
3JBU
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BU of 3jbu by Molmil
Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F.
Deposit date:2015-10-16
Release date:2016-01-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
3JBV
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BU of 3jbv by Molmil
Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F.
Deposit date:2015-10-16
Release date:2016-01-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
5SVD
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BU of 5svd by Molmil
Nop9, a new PUF-like protein, prevents premature pre-rRNA cleavage to correctly process mature 18S rRNA
Descriptor: Nucleolar protein 9
Authors:Zhang, J, Qiu, C, Hall, T.
Deposit date:2016-08-05
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA.
Nat Commun, 7, 2016
1A4F
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BU of 1a4f by Molmil
BAR-HEADED GOOSE HEMOGLOBIN (OXY FORM)
Descriptor: HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), OXYGEN MOLECULE, ...
Authors:Zhang, J, Gu, X.
Deposit date:1998-01-29
Release date:1998-04-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form).
J.Mol.Biol., 255, 1996
5T9P
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BU of 5t9p by Molmil
Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate
Descriptor: CHLORIDE ION, Ribosome biogenesis protein 15, SULFATE ION
Authors:Zhang, J, Gonzalez, E.L, Hall, M.T.T.
Deposit date:2016-09-09
Release date:2016-11-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate.
Nucleic Acids Res., 45, 2017
6MCZ
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BU of 6mcz by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Arachidonic Acid
Descriptor: ARACHIDONIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2018-09-03
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
8P0T
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BU of 8p0t by Molmil
CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor CP-17
Descriptor: Family T1, proteasome alpha subunit, threonine peptidase, ...
Authors:Silhan, J, Boura, E, Fajtova, P.
Deposit date:2023-05-10
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Tv20S proteasome in the complex with marizomib
To Be Published
6MD4
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BU of 6md4 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid
Descriptor: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), OLEIC ACID, ...
Authors:Shang, J, Kojetin, D.J.
Deposit date:2018-09-03
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MD1
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BU of 6md1 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Oleic acid
Descriptor: 2-chloro-5-nitro-N-phenylbenzamide, OLEIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2018-09-03
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MD2
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BU of 6md2 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Arachidonic acid
Descriptor: 2-chloro-5-nitro-N-phenylbenzamide, ARACHIDONIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2018-09-03
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018

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數據於2024-07-24公開中

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