6V9O

Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods

Summary for 6V9O

• Entry DOI: 10.2210/pdb6v9o/pdb
• Descriptor: GTPase HRas, Son of sevenless homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (10 entities in total)
• Functional Keywords: ras, sos, inhibitor, oncoprotein, protein-protein complex, mapk, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 96048.72

Authors

Phan, J.,Fesik, S.W. (deposition date: 2019-12-13, release date: 2020-12-16, Last modification date: 2023-11-15)

• Primary citation: Phan, J.,Fesik, S.W.; Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.799 Å)