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6V08
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BU of 6v08 by Molmil
Crystal structure of human recombinant Beta-2 glycoprotein I (hrB2GPI)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, SULFATE ION, ...
Authors:Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N.
Deposit date:2019-11-18
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
J.Biol.Chem., 295, 2020
2M01
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BU of 2m01 by Molmil
Solution structure of Kunitz-type neurotoxin LmKKT-1a from scorpion venom
Descriptor: Protease inhibitor LmKTT-1a
Authors:Luo, F, Jiang, L, Liu, M, Chen, Z, Wu, Y.
Deposit date:2012-10-15
Release date:2013-11-13
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Genomic and structural characterization of Kunitz-type peptide LmKTT-1a highlights diversity and evolution of scorpion potassium channel toxins.
Plos One, 8, 2013
3SGZ
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BU of 3sgz by Molmil
High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole.
Descriptor: 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 2
Authors:Chen, Z, Vignaud, C, Jaafar, A, Gueritte, F, Guenard, D, Lederer, F, Mathews, F.S.
Deposit date:2011-06-15
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.
Biochimie, 94, 2012
2P5B
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BU of 2p5b by Molmil
The complex structure of JMJD2A and trimethylated H3K36 peptide
Descriptor: FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ...
Authors:Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y.
Deposit date:2007-03-14
Release date:2007-06-12
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
5I9E
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BU of 5i9e by Molmil
Crystal structure of a nuclear actin ternary complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
Authors:Chen, Z, Cao, T.
Deposit date:2016-02-20
Release date:2016-07-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a nuclear actin ternary complex.
Proc.Natl.Acad.Sci.USA, 113, 2016
3CX8
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BU of 3cx8 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein alpha-13 subunit, MAGNESIUM ION, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
3CX6
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BU of 3cx6 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein alpha-13 subunit, MAGNESIUM ION, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
3CX7
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BU of 3cx7 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP-AlF4
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Glutamate Transporter Associated Protein 48, Guanine Nucleotide-Binding Protein Galpha 13, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
6BCA
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BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6DLM
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BU of 6dlm by Molmil
DHD127
Descriptor: DHD127_A, DHD127_B
Authors:Bick, M.J, Chen, Z, Baker, D.
Deposit date:2018-06-01
Release date:2018-12-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.753 Å)
Cite:Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
6DMA
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BU of 6dma by Molmil
DHD15_closed
Descriptor: DHD15_closed_A, DHD15_closed_B
Authors:Bick, M.J, Chen, Z, Baker, D.
Deposit date:2018-06-04
Release date:2018-12-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.363 Å)
Cite:Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
6DKM
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BU of 6dkm by Molmil
DHD131
Descriptor: DHD131_A, DHD131_B
Authors:Bick, M.J, Chen, Z, Baker, D.
Deposit date:2018-05-29
Release date:2018-12-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
6DM9
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BU of 6dm9 by Molmil
DHD15_extended
Descriptor: DHD15_extended_A, DHD15_extended_B, SULFATE ION
Authors:Bick, M.J, Chen, Z, Baker, D.
Deposit date:2018-06-04
Release date:2018-12-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
6DLC
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BU of 6dlc by Molmil
Designed protein DHD1:234_A, Designed protein DHD1:234_B
Descriptor: Designed protein DHD1:234_A, Designed protein DHD1:234_B
Authors:Bick, M.J, Chen, Z, Baker, D.
Deposit date:2018-05-31
Release date:2018-12-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.261 Å)
Cite:Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
6BB3
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BU of 6bb3 by Molmil
Lactate Dehydrogenase in complex with inhibitor 3-((2-chlorophenyl)thio)-6-(6-((4-fluorophenyl)amino)pyridin-2-yl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one
Descriptor: (6R)-3-[(2-chlorophenyl)sulfanyl]-6-{6-[(4-fluorophenyl)amino]pyridin-2-yl}-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Chen, Z, Eigenbrot, C.
Deposit date:2017-10-16
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-guided optimization and in vivo activities of hydroxylactone and hydroxylactam Inhibitors of Human Lactate Dehydrogenase
To Be Published
5X3E
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BU of 5x3e by Molmil
kinesin 6
Descriptor: IODIDE ION, Kinesin-like protein, SULFATE ION
Authors:Chen, Z, Guan, R, Zhang, L.
Deposit date:2017-02-04
Release date:2017-04-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin
Nat Commun, 8, 2017
7VVY
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BU of 7vvy by Molmil
TRA module of NuA4
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
Authors:Chen, Z, Qu, K.
Deposit date:2021-11-09
Release date:2022-08-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
7VVU
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BU of 7vvu by Molmil
NuA4 HAT module bound to the nucleosome
Descriptor: CARBOXYMETHYL COENZYME *A, Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, ...
Authors:Chen, Z, Qu, K.
Deposit date:2021-11-09
Release date:2022-08-10
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
5ZBM
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BU of 5zbm by Molmil
Structure of glycolate oxidase containing FMN from Nicotiana benthamiana
Descriptor: FLAVIN MONONUCLEOTIDE, Glycolate oxidase
Authors:Chen, Z, Liu, Y.
Deposit date:2018-02-12
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of glycolate oxidase from Nicotiana benthamiana reveal a conserved pH sensor affecting the binding of FMN.
Biochem.Biophys.Res.Commun., 503, 2018
5ZBN
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BU of 5zbn by Molmil
Structure of glycolate oxidase without FMN from Nicotiana benthamiana
Descriptor: Glycolate oxidase, PHOSPHATE ION
Authors:Chen, Z, Liu, Y.
Deposit date:2018-02-12
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structures of glycolate oxidase from Nicotiana benthamiana reveal a conserved pH sensor affecting the binding of FMN.
Biochem.Biophys.Res.Commun., 503, 2018
5Z0Y
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BU of 5z0y by Molmil
Crystallization and structure determination of cytoplasm serine hydroxymethyltransferase (SHMT) from Pichia pastoris
Descriptor: GLYCEROL, Serine hydroxymethyltransferase
Authors:Chen, Z, Zhang, M.
Deposit date:2017-12-22
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and function of cytoplasmic serine hydroxymethyltransferase from Pichia pastoris
Biochem. Biophys. Res. Commun., 496, 2018
6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
7U1B
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BU of 7u1b by Molmil
Crystal structure of EstG in complex with tantalum cluster
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICINE, Beta-lactamase domain-containing protein, ...
Authors:Chen, Z, Gabelli, S.B.
Deposit date:2022-02-20
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:EstG is a novel esterase required for cell envelope integrity in Caulobacter.
Curr.Biol., 33, 2023

226707

數據於2024-10-30公開中

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