1W1A
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![BU of 1w1a by Molmil](/molmil-images/mine/1w1a) | Structure of Bacillus subtilis PdaA in complex with NAG, a family 4 Carbohydrate esterase. | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CADMIUM ION, GLYCEROL, ... | Authors: | Blair, D.E, van Aalten, D.M.F. | Deposit date: | 2004-06-18 | Release date: | 2005-01-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structures of Bacillus subtilis PdaA, a family 4 carbohydrate esterase, and a complex with N-acetyl-glucosamine. FEBS Lett., 570, 2004
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2G5R
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![BU of 2g5r by Molmil](/molmil-images/mine/2g5r) | Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Sialic acid-binding Ig-like lectin 7, ... | Authors: | Attrill, H, Crocker, P.R, van Aalten, D.M. | Deposit date: | 2006-02-23 | Release date: | 2006-06-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design. Biochem.J., 397, 2006
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6IBO
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![BU of 6ibo by Molmil](/molmil-images/mine/6ibo) | Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability | Descriptor: | (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, ALA-VAL-SER-ARG-ALA, PHOSPHATE ION, ... | Authors: | Gundogdu, M, van Aalten, D.M.F. | Deposit date: | 2018-11-30 | Release date: | 2019-07-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability. Proc.Natl.Acad.Sci.USA, 116, 2019
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2FJ9
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![BU of 2fj9 by Molmil](/molmil-images/mine/2fj9) | High resolution crystal structure of the unliganded human ACBP | Descriptor: | Acyl-CoA-binding protein, CHLORIDE ION, LEAD (II) ION, ... | Authors: | Taskinen, J.P, van Aalten, D.M, Knudsen, J, Wierenga, R.K. | Deposit date: | 2006-01-02 | Release date: | 2006-10-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High resolution crystal structures of unliganded and liganded human liver ACBP reveal a new mode of binding for the acyl-CoA ligand. Proteins, 66, 2006
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6Q4M
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![BU of 6q4m by Molmil](/molmil-images/mine/6q4m) | Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation | Descriptor: | (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, PHOSPHATE ION, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | Authors: | Gundogdu, M, van Aalten, D.M.F. | Deposit date: | 2018-12-06 | Release date: | 2019-12-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation To Be Published
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2W3Z
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![BU of 2w3z by Molmil](/molmil-images/mine/2w3z) | Structure of a Streptococcus mutans CE4 esterase | Descriptor: | PHOSPHATE ION, PUTATIVE DEACETYLASE, ZINC ION | Authors: | Deng, D.M, Urch, J.E, ten Cate, J.M, Rao, V.A, van Aalten, D.M.F, Crielaard, W. | Deposit date: | 2008-11-17 | Release date: | 2008-12-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Streptococcus Mutans Smu.623C Codes for a Functional, Metal Dependent Polysaccharide Deacetylase that Modulates Interactions with Salivary Agglutinin. J.Bacteriol., 191, 2009
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6EOU
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![BU of 6eou by Molmil](/molmil-images/mine/6eou) | |
1OGB
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![BU of 1ogb by Molmil](/molmil-images/mine/1ogb) | Chitinase b from Serratia marcescens mutant D142N | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION | Authors: | Vaaje-Kolstad, G, Houston, D.R, Rao, F.V, Peter, M.G, Synstad, B, van Aalten, D.M.F, Eijsink, V.G.H. | Deposit date: | 2003-04-29 | Release date: | 2004-04-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin Biochim.Biophys.Acta, 1696, 2004
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1OGG
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![BU of 1ogg by Molmil](/molmil-images/mine/1ogg) | chitinase b from serratia marcescens mutant d142n in complex with inhibitor allosamidin | Descriptor: | 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, CHITINASE B, ... | Authors: | Vaaje-Kolstad, G, Houston, D.R, Rao, F.V, Peter, M.G, Synstad, B, van Aalten, D.M.F, Eijsink, V.G.H. | Deposit date: | 2003-04-30 | Release date: | 2004-04-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure of the D142N Mutant of the Family 18 Chitinase Chib from Serratia Marcescens and its Complex with Allosamidin Biochim.Biophys.Acta, 1696, 2004
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7OYL
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![BU of 7oyl by Molmil](/molmil-images/mine/7oyl) | Phosphoglucose isomerase of Aspergillus fumigatus in complexed with Glucose-6-phosphate | Descriptor: | 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Raimi, O.G, Yan, K, Fang, W, van Aalten, D.M.F. | Deposit date: | 2021-06-24 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis. Mbio, 13, 2022
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7P5O
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7PIZ
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![BU of 7piz by Molmil](/molmil-images/mine/7piz) | |
7PJC
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![BU of 7pjc by Molmil](/molmil-images/mine/7pjc) | |
7PPR
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![BU of 7ppr by Molmil](/molmil-images/mine/7ppr) | |
1EAZ
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![BU of 1eaz by Molmil](/molmil-images/mine/1eaz) | Crystal structure of the phosphoinositol (3,4)-bisphosphate binding PH domain of TAPP1 from human. | Descriptor: | CITRIC ACID, TANDEM PH DOMAIN CONTAINING PROTEIN-1 | Authors: | Thomas, C.C, Dowler, S, Deak, M, Alessi, D.R, Van Aalten, D.M.F. | Deposit date: | 2001-07-17 | Release date: | 2002-07-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity Biochem.J., 358, 2001
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6I5X
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![BU of 6i5x by Molmil](/molmil-images/mine/6i5x) | Crystal structure of Aspergillus fumigatus phosphomannomutase | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Zhang, Y, Raimi, O.G, Ferenbach, A.T, van Aalten, D.M.F. | Deposit date: | 2018-11-15 | Release date: | 2019-11-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Aspergillus fumigatus phosphomannomutase To Be Published
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6IBU
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![BU of 6ibu by Molmil](/molmil-images/mine/6ibu) | Apo Crh5 transglycosylase | Descriptor: | GLYCEROL, Probable glycosidase crf1 | Authors: | Bartual, S.G, Fang, W, van Aalten, D.M.F. | Deposit date: | 2018-11-30 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases. Nat Commun, 10, 2019
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6IBW
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![BU of 6ibw by Molmil](/molmil-images/mine/6ibw) | Crh5 transglycosylase in complex with NAG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Probable glycosidase crf1 | Authors: | Fang, W, Bartual, S.G, van Aalten, D.M.F. | Deposit date: | 2018-12-01 | Release date: | 2019-02-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases. Nat Commun, 10, 2019
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1ODV
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![BU of 1odv by Molmil](/molmil-images/mine/1odv) | Photoactive yellow protein 1-25 deletion mutant | Descriptor: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | Authors: | Vreede, J, Van Der horst, M.A, Hellingwerf, K.J, Crielaard, W, Van Aalten, D.M.F. | Deposit date: | 2003-03-14 | Release date: | 2003-03-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Pas Domains.Common Structure and Common Flexibility J.Biol.Chem., 278, 2003
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1GOI
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![BU of 1goi by Molmil](/molmil-images/mine/1goi) | Crystal structure of the D140N mutant of chitinase B from Serratia marcescens at 1.45 A resolution | Descriptor: | CHITINASE B, GLYCEROL, SULFATE ION | Authors: | Kolstad, G, Synstad, B, Eijsink, V.G.H, Van Aalten, D.M.F. | Deposit date: | 2001-10-21 | Release date: | 2001-11-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of the D140N Mutant of Chitinase B from Serratia Marcescens at 1.45 A Resolution. Acta Crystallogr.,Sect.D, 58, 2002
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5OXD
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![BU of 5oxd by Molmil](/molmil-images/mine/5oxd) | |
1OKZ
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![BU of 1okz by Molmil](/molmil-images/mine/1okz) | Structure of human PDK1 kinase domain in complex with UCN-01 | Descriptor: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, 7-HYDROXYSTAUROSPORINE, GLYCEROL, ... | Authors: | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | Deposit date: | 2003-08-01 | Release date: | 2004-07-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition Biochem.J., 375, 2003
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1OKY
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![BU of 1oky by Molmil](/molmil-images/mine/1oky) | Structure of human PDK1 kinase domain in complex with staurosporine | Descriptor: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, STAUROSPORINE, ... | Authors: | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | Deposit date: | 2003-08-01 | Release date: | 2004-07-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition Biochem.J., 375, 2003
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2Y8V
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![BU of 2y8v by Molmil](/molmil-images/mine/2y8v) | Structure of chitinase, ChiC, from Aspergillus fumigatus. | Descriptor: | CLASS III CHITINASE, PUTATIVE, SODIUM ION | Authors: | Rush, C.L, Schuettelkopf, A.W, Gay, L.M, van Aalten, D.M.F. | Deposit date: | 2011-02-10 | Release date: | 2012-02-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure of Chitinase, Chic, from Aspergillus Fumigatus. To be Published
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2YDQ
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![BU of 2ydq by Molmil](/molmil-images/mine/2ydq) | CpOGA D298N in complex with hOGA-derived O-GlcNAc peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BIFUNCTIONAL PROTEIN NCOAT, CADMIUM ION, ... | Authors: | Schimpl, M, Borodkin, V.S, Gray, L.J, van Aalten, D.M.F. | Deposit date: | 2011-03-24 | Release date: | 2012-03-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Synergy of Peptide and Sugar in O-Glcnacase Substrate Recognition. Chem.Biol., 19, 2012
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