7F3Q
| SARS-CoV-2 RBD in complex with A5-10 Fab and A34-2 Fab | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A34-2 Fab, ... | Authors: | Dou, Y, Wang, X, Liu, P, Lu, B, Wang, K. | Deposit date: | 2021-06-16 | Release date: | 2022-06-22 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Development of neutralizing antibodies against SARS-CoV-2, using a high-throughput single-B-cell cloning method. Antib Ther, 6, 2023
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6JE9
| Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | Descriptor: | AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-04 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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6JE4
| Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | Descriptor: | 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ... | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-04 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.069 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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6JDV
| Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state | Descriptor: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, MAGNESIUM ION, ... | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-02 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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6JDQ
| Crystal structure of Nme1Cas9 in complex with sgRNA | Descriptor: | CRISPR-associated endonuclease Cas9, sgRNA | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-02 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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1CIX
| THREE-DIMENSIONAL STRUCTURE OF ANTIMICROBIAL PEPTIDE TACHYSTATIN A ISOLATED FROM HORSESHOE CRAB | Descriptor: | PROTEIN (TACHYSTATIN A) | Authors: | Fujitani, N, Kawabata, S, Osaki, T, Kumaki, Y, Demura, M, Nitta, K, Kawano, K. | Deposit date: | 1999-04-06 | Release date: | 2002-05-01 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of the antimicrobial peptide tachystatin A. J.Biol.Chem., 277, 2002
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1K37
| NMR Structure of human Epiregulin | Descriptor: | Epiregulin | Authors: | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | Deposit date: | 2001-10-02 | Release date: | 2003-09-30 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity Febs Lett., 553, 2003
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1K36
| NMR Structure of human Epiregulin | Descriptor: | Epiregulin | Authors: | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | Deposit date: | 2001-10-02 | Release date: | 2003-09-30 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity Febs Lett., 553, 2003
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6F7H
| Crystal structure of human AQP10 | Descriptor: | Aquaporin-10, GLYCEROL, nonyl beta-D-glucopyranoside | Authors: | Gotfryd, K, Wang, K, Missel, J.W, Pedersen, P.A, Gourdon, P. | Deposit date: | 2017-12-08 | Release date: | 2018-11-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Human adipose glycerol flux is regulated by a pH gate in AQP10. Nat Commun, 9, 2018
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1BQF
| GROWTH-BLOCKING PEPTIDE (GBP) FROM PSEUDALETIA SEPARATA | Descriptor: | PROTEIN (GROWTH-BLOCKING PEPTIDE) | Authors: | Aizawa, T, Fujitani, N, Hayakawa, Y, Ohnishi, A, Ohkubo, T, Kwano, K, Hikichi, K, Nitta, K. | Deposit date: | 1998-08-09 | Release date: | 1998-12-09 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of an insect growth factor, growth-blocking peptide. J.Biol.Chem., 274, 1999
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1IWC
| TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase | Descriptor: | gastric H/K-ATPase | Authors: | Fujitani, N, Kanagawa, M, Aizawa, T, Ohkubo, T, Kaya, S, Demura, M, Kawano, K, Taniguchi, K, Nitta, K. | Deposit date: | 2002-05-02 | Release date: | 2002-11-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure determination and conformational change induced by tyrosine phosphorylation of the N-terminal domain of the alpha-chain of pig gastric H+/K+-ATPase Biochem.Biophys.Res.Commun., 300, 2003
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1IWF
| Solution structure of the N-terminal domain of pig gastric H/K-ATPase | Descriptor: | gastric H/K-ATPase | Authors: | Fujitani, N, Kanagawa, M, Aizawa, T, Ohkubo, T, Kaya, S, Demura, M, Kawano, K, Taniguchi, K, Nitta, K. | Deposit date: | 2002-05-06 | Release date: | 2002-11-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure determination and conformational change induced by tyrosine phosphorylation of the N-terminal domain of the alpha-chain of pig gastric H+/K+-ATPase Biochem.Biophys.Res.Commun., 300, 2003
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8JR9
| Small molecule agonist (PCO371) bound to human parathyroid hormone receptor type 1 (PTH1R) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha-1, ... | Authors: | Zhao, L, He, Q, Yuan, Q, Gu, Y, He, X, Shan, H, Li, J, Wang, K, Li, Y, Hu, W, Wu, K, Shen, J, Xu, H.E. | Deposit date: | 2023-06-16 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Conserved class B GPCR activation by a biased intracellular agonist. Nature, 621, 2023
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1KM7
| Solution Structure and Backbone Dynamics of GABARAP, GABAA Receptor Associated Protein | Descriptor: | GABA(A) Receptor Associated Protein | Authors: | Kouno, T, Miura, K, Tada, M, Kanematsu, T, Tate, S, Shirakawa, M, Hirata, M, Kawano, K. | Deposit date: | 2001-12-14 | Release date: | 2003-10-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | 1H, 13C and '5N resonance assignments of GABARAP, GABAA receptor associated protein. J.Biomol.Nmr, 22, 2002
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1KLV
| Solution Structure and Backbone Dynamics of GABARAP, GABAA Receptor associated protein | Descriptor: | GABA(A) Receptor associated protein | Authors: | Kouno, T, Miura, K, Tada, M, Kanematsu, T, Tate, S, Shirakawa, M, Hirata, M, Kawano, K. | Deposit date: | 2001-12-13 | Release date: | 2003-10-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | 1H, 13C and '5N resonance assignments of GABARAP, GABAA receptor associated protein. J.Biomol.Nmr, 22, 2002
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1GD6
| STRUCTURE OF THE BOMBYX MORI LYSOZYME | Descriptor: | LYSOZYME | Authors: | Matsuura, A, Aizawa, T, Yao, M, Kawano, K, Tanaka, I, Nitta, K. | Deposit date: | 2000-09-19 | Release date: | 2001-03-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures. Biochemistry, 41, 2002
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2Z2F
| X-ray Crystal Structure of Bovine Stomach Lysozyme | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme C-2, SODIUM ION | Authors: | Akieda, D, Nonaka, Y, Watanabe, N, Tanaka, I, Kamiya, M, Aizawa, T, Nitta, K, Demura, M, Kawano, K. | Deposit date: | 2007-05-21 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Stability of Bovine Stomach Lysozyme in Acidic Condition To be Published
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3FXO
| Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Phosphate at 1 mM of Mn2+ | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A | Authors: | Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. | Deposit date: | 2009-01-21 | Release date: | 2010-01-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the Mn2+-dependent activation of human PPM1A To be published
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4S39
| IspG in complex with HMBPP | Descriptor: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, GLYCEROL, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Guodong, R, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-04-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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4S3C
| IspG in complex with Epoxide Intermediate | Descriptor: | (3S)-1,3-dihydroxy-4-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-2-methylbut-2-ylium, carbokation intermediate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-05-06 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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4S3E
| IspG in complex with Inhibitor 7 (compound 1061) | Descriptor: | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, GLYCEROL, IRON/SULFUR CLUSTER, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-04-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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4S3B
| IspG in complex with Intermediate II | Descriptor: | (3S)-1,3-dihydroxy-4-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-2-methylbut-2-ylium, carbokation intermediate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-04-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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7N6W
| Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U2 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, S, Wang, K, Mao, Y. | Deposit date: | 2021-06-09 | Release date: | 2021-09-22 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer. J.Virol., 95, 2021
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7N6U
| Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U1 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 | Descriptor: | 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, S, Wang, K, Mao, Y. | Deposit date: | 2021-06-09 | Release date: | 2021-09-22 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer. J.Virol., 95, 2021
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4S38
| IspG in complex MEcPP | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, ... | Authors: | Quitterer, F, Frank, A, Wang, K, Guodong, R, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | Deposit date: | 2015-01-26 | Release date: | 2015-04-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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