4S38

IspG in complex MEcPP

Summary for 4S38

Related4G9P 2Y0F 3NOY 4S39 4S3A 4S3B 4S3C 4S3D 4S3E 4S3F
Descriptor4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, IRON/SULFUR CLUSTER, ... (8 entities in total)
Functional Keywordsmethylerythritol-phosphate pathway, terpene biosynthesis, iron-sulfur enzymes, reaction mechanisms, drug development, oxidoreductase
Biological sourceThermus thermophilus HB8
Total number of polymer chains1
Total molecular weight45829.79
Authors
Quitterer, F.,Frank, A.,Wang, K.,Guodong, R.,O'Dowd, B.,Li, J.,Guerra, F.,Abdel-Azeim, S.,Bacher, A.,Eppinger, J.,Oldfield, E.,Groll, M. (deposition date: 2015-01-26, release date: 2015-04-29, Last modification date: 2015-07-01)
Primary citation
Quitterer, F.,Frank, A.,Wang, K.,Rao, G.,O'Dowd, B.,Li, J.,Guerra, F.,Abdel-Azeim, S.,Bacher, A.,Eppinger, J.,Oldfield, E.,Groll, M.
Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE).
J.Mol.Biol., 427:2220-2228, 2015
PubMed: 25868383 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2015.04.002
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.144402.8%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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