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2WLI
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BU of 2wli by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: KIRBAC3.1 POTASSIUM CHANNEL, POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLH
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BU of 2wlh by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: CHLORIDE ION, POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2X6B
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BU of 2x6b by Molmil
Potassium Channel from Magnetospirillum Magnetotacticum
Descriptor: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, BARIUM ION, PHOSPHOCHOLINE, ...
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, Vandenberg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2010-02-15
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2X6C
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BU of 2x6c by Molmil
Potassium Channel from Magnetospirillum Magnetotacticum
Descriptor: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, PHOSPHOCHOLINE, ...
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, Vandenberg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2010-02-15
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLL
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BU of 2wll by Molmil
POTASSIUM CHANNEL FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor: DIUNDECYL PHOSPHATIDYL CHOLINE, MAGNESIUM ION, POTASSIUM CHANNEL, ...
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, VandenBerg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
3FDL
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BU of 3fdl by Molmil
Bim BH3 peptide in complex with Bcl-xL
Descriptor: Apoptosis regulator Bcl-X, Bcl-2-like protein 11
Authors:Fairlie, W.D, Lee, E.F, Smith, B.J, Czabotar, P.E, Colman, P.M.
Deposit date:2008-11-26
Release date:2009-03-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L)
Angew.Chem.Int.Ed.Engl., 48, 2009
3FDM
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BU of 3fdm by Molmil
alpha/beta foldamer in complex with Bcl-xL
Descriptor: 1,2-ETHANEDIOL, Apoptosis regulator Bcl-X, alpha/beta-peptide foldamer
Authors:Fairlie, W.D, Lee, E.F, Smith, B.J, Czabotar, P.E, Colman, P.M, Sadowsky, J.D, Peterson-Kaufman, K.J, Gellman, S.H.
Deposit date:2008-11-26
Release date:2009-03-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L)
Angew.Chem.Int.Ed.Engl., 48, 2009
6V4M
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BU of 6v4m by Molmil
Trichuris suis BCL-2
Descriptor: BCL-2, CHLORIDE ION, SULFATE ION
Authors:Fairlie, W.D, Lee, E.F, Smith, B.J.
Deposit date:2019-11-28
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Diversity in the intrinsic apoptosis pathway of nematodes.
Commun Biol, 3, 2020
5VAX
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BU of 5vax by Molmil
Bcl-2 complex with Beclin 1 BH3 domain
Descriptor: Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1
Authors:Lee, E.F, Smith, B.J, Yao, S, Fairlie, W.D.
Deposit date:2017-03-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Bcl-2 complex with Beclin 1 pT108 BH3 domain
To Be Published
5VAU
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BU of 5vau by Molmil
Bcl-2 complex with Beclin 1 BH3 domain
Descriptor: Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1
Authors:Lee, E.F, Smith, B.J, Yao, S, Fairlie, W.D.
Deposit date:2017-03-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Bcl-2 complex with Beclin 1 BH3 domain
To Be Published
5VAY
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BU of 5vay by Molmil
Bcl-2 complex with Beclin 1 T108D BH3 domain
Descriptor: Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1
Authors:Lee, E.F, Smith, B.J, Yao, S, Fairlie, W.D.
Deposit date:2017-03-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Bcl-2 complex with Beclin 1 pT108 BH3 domain
To Be Published
5WBT
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BU of 5wbt by Molmil
Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING
Descriptor: Insulin
Authors:Glidden, M.D, Yang, Y, Wickramasinghe, N.P, Weiss, M.A.
Deposit date:2017-06-29
Release date:2017-11-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.
J. Biol. Chem., 293, 2018
4WAT
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BU of 4wat by Molmil
Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMIDAZOLE, PfRh5
Authors:Chen, L.
Deposit date:2014-09-01
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes.
Elife, 3, 2014
5JYQ
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BU of 5jyq by Molmil
Structure of Conus Geographus insulin G1
Descriptor: Insulin 1, Insulin 1b, SULFATE ION
Authors:Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
Deposit date:2016-05-15
Release date:2016-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
5J3H
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BU of 5j3h by Molmil
Human insulin receptor domains L1-CR in complex with peptide S519C16 and 83-7 Fv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lawrence, M, Menting, J, Lawrence, C.
Deposit date:2016-03-30
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor.
J.Biol.Chem., 291, 2016
7LK4
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BU of 7lk4 by Molmil
Crystal structure of BAK L100A in complex with activating antibody fragments
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7D10 antibody VH fragment, 7D10 antibody VL fragment, ...
Authors:Robin, Y.A, Colman, P.M.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the alpha 1-alpha 2 loop in BAK activation.
Cell Death Differ., 29, 2022
7KD6
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BU of 7kd6 by Molmil
Insulin Receptor L1-CR plus alphaCT fragment in co-complex with Fv 83-7 and single-chain insulin SCI-b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lawrence, M.C, Menting, J.G.
Deposit date:2020-10-08
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
Biophys.J., 2022
4QVX
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BU of 4qvx by Molmil
Discovery of a Potent and Selective BCL-XL Inhibitor That Demonstrates Thrombocytopenia and Inhibits Tumor Growth in Vivo
Descriptor: 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-(3-{4-[3-(dimethylamino)prop-1-yn-1-yl]-2-fluorophenoxy}propyl)-1,3-thiazole-4-carboxylic acid, Bcl-2-like protein 1
Authors:Park, C.H.
Deposit date:2014-07-16
Release date:2015-07-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.
ACS MED.CHEM.LETT., 5, 2014
2Y6W
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BU of 2y6w by Molmil
Structure of a Bcl-w dimer
Descriptor: BCL-2-LIKE PROTEIN 2, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL
Authors:Lee, E.F, Evangelista, M, Pettikiriarachchi, A, Dogovski, C, Perugini, M.A, Colman, P.M, Fairlie, W.D.
Deposit date:2011-01-27
Release date:2011-10-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Bcl-W Domain-Swapped Dimer: Implications for the Function of Bcl-2 Family Proteins.
Structure, 19, 2011
1YWG
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BU of 1ywg by Molmil
The structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase
Authors:Satchell, J.F, Klonis, N, Malby, R.L, Adisa, A, Alpyurek, A.E, Colman, P.M, Tilley, L.
Deposit date:2005-02-17
Release date:2005-11-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum.
Acta Crystallogr.,Sect.D, 61, 2005
6VEP
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BU of 6vep by Molmil
Human insulin in complex with the human insulin microreceptor in turn in complex with Fv 83-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lawrence, M.C, Menting, J.G.T.
Deposit date:2020-01-02
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Nat.Struct.Mol.Biol., 27, 2020
6UXQ
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BU of 6uxq by Molmil
Crystal structure of BAK core domain BH3-groove-dimer in complex with POPC and C8E4
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ...
Authors:Cowan, A.D, Colman, P.M, Czabotar, P.E.
Deposit date:2019-11-07
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:BAK core dimers bind lipids and can be bridged by them.
Nat.Struct.Mol.Biol., 27, 2020
6UXN
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BU of 6uxn by Molmil
Crystal structure of BAK core domain BH3-groove-dimer in complex with phosphatidylserine
Descriptor: Bcl-2 homologous antagonist/killer, GLYCEROL, O-[(R)-{[(2R)-2,3-bis(octanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Cowan, A.D, Colman, P.M, Czabotar, P.E.
Deposit date:2019-11-07
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:BAK core dimers bind lipids and can be bridged by them.
Nat.Struct.Mol.Biol., 27, 2020
6UXP
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BU of 6uxp by Molmil
Crystal structure of BAK core domain BH3-groove-dimer in complex with phosphatidylglycerol
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL), Bcl-2 homologous antagonist/killer, GLYCEROL
Authors:Cowan, A.D, Colman, P.M, Czabotar, P.E.
Deposit date:2019-11-07
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.492 Å)
Cite:BAK core dimers bind lipids and can be bridged by them.
Nat.Struct.Mol.Biol., 27, 2020
6VET
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BU of 6vet by Molmil
Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI
Descriptor: Insulin A chain, Insulin B chain
Authors:Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X.
Deposit date:2020-01-02
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Nat.Struct.Mol.Biol., 27, 2020

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數據於2024-06-12公開中

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